Evaluation of Iron Supplementation During Darbepoetin Alfa Treatment in Prophylaxis of Severe Anaemia Chemo-Induced

Inclusion Criteria:

• Age ≥ 18 years
• Well-informed written consent, signed by the patient
• Patient picked up for solid tumor treatment, whichever the localization, with or without metastasis
• Patient revealing, before or during chemotherapy, a moderate anemia, that means: Men: 9<Hb<12 g/dl; Women: 9<Hb<11 g/dl.
• Patient for who at least four chemotherapy cycles are planed (eight in case of weekly chemotherapy) after inclusion in the study
• Patients with life expectancy higher than three months
• Patient with general conditions compatible with the study's follow-up

Exclusion Criteria:

• Contra-indication for Venofer
• Anemia which can have curative treatment
• Bloody transfusion during the previous four weeks
• Documented or suspected medullary invasion
• Uncontrolled arterial hypertension
• Acute bacterial infection
• Transferrin saturation's coefficient
• Pregnancy
• Ferric salts oral treatment interrupted since less than one week
• Patient with bad french language's comprehension
• Patient with a major psychiatric pathology
• Patient under guardianship, trusteeship or justice safeguard