Neurostimulation-enhanced Behavioral Remediation of Social Cognition in Schizophrenia (NSOCOG)

Inclusion Criteria:

• be between 18 and 45-years-old
• have normal hearing assessed by the Five-minute hearing test
• have French as a first language
• be able to provide written informed consent
• be right handed as measured by the Edinburgh handedness scale
• covered by, or having the right to Social Security
• informed consent signed
• patients with diagnosis of schizoprenia or schizoaffective disorder-depressive type as determined by the SCID Diagnostic Interview for DSM-V and administered by a clinician
• clinically stable and on a stable medication regiment for the past 3 months

Exclusion Criteria:

• significant medical or neurological illness or history of fetal alcohol exposure that may increase risks of the study, significantly affect brain function, or impede participation
• substance dependence (except nicotine) or abuse not in remission within the past six months or recent use presenting the possibility of acute intoxication or withdrawal
• a history of any Axis I psychiatric disorder except those required in the inclusion criteria, any history of pervasive developmental disorder or mental retardation
• for Visit 3: If participating in tCDS Contraindications for tDCS (pacemaker or brain stimulator) and/or MRI (neurologic stimulator, pacemaker, cardiac defibrillator, cardiac prosthesis, vascular prosthesis, intracranial clips or clamps, cerebrospinal fluid derivation, metallic splinters in the eyes)
• patients under curatorship/guardianship and whose clinical condition requires inpatient procedure under constraint
• healthy controls must not be currently using psychoactive médications or have a first-degree relative with a psychotic disorder