Early Incidence of Occupational Asthma Among Bakers, Pastry-makers and Hairdressers

Evolution of the Incidence of Occupational Asthma at the Beginning of the Activity of Young Bakers, Pastry-makers and Hairdressers, and Exploration of Its Risk Factors

Patrocinadores

Patrocinador principal: Central Hospital, Nancy, France

Colaborador: Institut National de la Santé Et de la Recherche Médicale, France
University of Nancy

Fuente Central Hospital, Nancy, France
Resumen breve

Background: Occupational exposures are thought to be responsible for 10-15% of new-onset asthma cases in adults, with disparities across sectors. Because most of the data are derived from registries and cross-sectional studies, little is known about incidence of occupational asthma (OA) during the first years after inception of exposure. This study focuses on this early asthma onset period among young workers in the bakery, pastry making and hairdressing sectors in order to assess early incidence of OA in these "at risk" occupations according to exposure duration, and to identify risk factors of OA.

Methods: This study is a longitudinal retrospective study with a nested case-control to identify risk factors of OA. The assessment of incidence evolution is made by exploring a series of promotions (or retrospective cohorts) with increasing duration since at work. The study population is composed of subjects who graduated between 2001 and 2006 in sectors where they experience exposure to organic or inorganic allergenic or irritant compounds (with an objective of 150 subjects by year) and 250 young workers with no specific occupational exposure.

This study is a descriptive, monocentric, longitudinal and retrospective study with cross-sectional measurements.

Estado general Completed
Fecha de inicio December 2008
Fecha de Terminación June 2010
Fecha de finalización primaria January 2010
Tipo de estudio Observational
Resultado primario
Medida Periodo de tiempo
The early incidence of OA among young workers according to their sector of activity and exposure duration. 3-6 months after tle last inclusion
Resultado secundario
Medida Periodo de tiempo
The identification of risk factors of OA. 3-6 months after the last inclusion
Inscripción 866
Condición
Elegibilidad

Método de muestreo: Non-Probability Sample

Criterios:

Inclusion Criteria:

- for the exposed group: to be graduated between 2001 and 2006 from nine vocational schools in Lorraine, North-Eastern France

- for the "non-exposed" group: to be graduated in 2001 in the sale or the food sectors (butcher, pork butcher, caterer, cook job,…) from the same vocational schools

Exclusion Criteria:

- asthma diagnosed before apprenticeship

- for the "non-exposed" group: to have worked previously or later in a sector at risk with OA

Género: All

Edad mínima: N/A

Edad máxima: N/A

Voluntarios Saludables: Accepts Healthy Volunteers

Oficial general
Ubicación
Instalaciones: CHU Nancy
Ubicacion Paises

France

Fecha de verificación

March 2016

Fiesta responsable

Tipo: Sponsor

Palabras clave
Tiene acceso ampliado No
Condición Examinar
Grupo de brazo

Etiqueta: Young workers

Descripción: Exposed young workers graduated in sectors at risk of occupational asthma (bakery, pastry-making or hairdressing) "Non-exposed" young workers graduated in sectors without specific occupational exposure as the sale or the food sectors.

Acrónimo ABCD
Información de diseño del estudio

Modelo de observación: Cohort

Perspectiva de tiempo: Retrospective

Fuente: ClinicalTrials.gov