Prevalence of Preoperative Dehydration in Major Elective Urologic Surgery and Its Impact on Postoperative Outcome

Prevalence of Preoperative Dehydration in Major Elective Urologic Surgery and Its Impact on Postoperative Outcome

Patrocinadores

Patrocinador principal: University Hospital Inselspital, Berne

Fuente University Hospital Inselspital, Berne
Resumen breve

The primary objective of this study is to measure the prevalence of preoperative dehydration in elective major abdominal urologic surgery when we apply our daily standard operation procedures. Secondary objectives are to assess the impact of preoperative dehydration on postoperative outcome. The hypothesis is that preoperative dehydration leads to more postoperative complications.

Descripción detallada

The information about the impact of preoperative dehydration on postoperative outcome is conflicting. One of the reported difficulties of the studies in this field is to get adequate power for statistical significance. The incidence of preoperative dehydration in different surgical populations has been reported in about one third of patients. The prevalence in the urologic population is not known.

This is a monocentric observational study with no study intervention. The goal is to consecutively include all patients undergoing major urologic surgery during 365 days who meet the inclusion criteria to assess the prevalence of preoperative dehydration in elective major abdominal urologic surgery when the standard operation procedures of the University Hospital Bern are applied.

Estado general Terminated
Fecha de inicio February 12, 2019
Fecha de Terminación March 30, 2020
Fecha de finalización primaria March 16, 2020
Tipo de estudio Observational
Resultado primario
Medida Periodo de tiempo
Prevalence of Dehydration at Induction of Anesthesia Time point 0: time (estimated between 7am and 4pm on day of surgery) at Induction of Anesthesia for Major Urologic Surgery
Resultado secundario
Medida Periodo de tiempo
Postoperative Nausea and Vomiting (PONV) 6 hours, 24 hours and 48 hours postoperatively
Gastrointestinal function (flatus/defecation) postoperatively 24 hours and 48 hours postoperatively
Renal function postoperatively 6 hours, 24 hours and 48 hours postoperatively
Fluid balance within 24 hours postoperatively
Complications within hospitalization within hospital stay, expected to be within 2 weeks postoperatively
Quality of recovery 24 hours postoperatively
Inscripción 188
Condición
Elegibilidad

Método de muestreo: Probability Sample

Criterios:

Inclusion Criteria:

- >18 years old

- Major elective urologic surgery i. Prostate surgery ii. Bladder surgery iii. Kidney surgery iv. Various laparotomies / laparoscopies (e.g. retroperitoneal lymphadenectomy)

- Standard procedure planned

- Standard perioperative management planned

- Informed consent

Exclusion Criteria:

- Preoperative iv-fluids

- Pregnancy (which is a contraindication to this type of surgery per se)

- Inability to give informed consent (e.g. severe psychiatric disorder, dementia)

- Inability to complete the Quality of Recovery (QoR) questionnaire

- Enrolment of the investigator, his/her family members, employees and other dependent persons

Género: All

Edad mínima: 18 Years

Edad máxima: N/A

Voluntarios Saludables: No

Oficial general
Apellido Papel Afiliación
Lukas M Löffel, M.D. Principal Investigator Inselspital University Hospital Bern
Ubicación
Instalaciones: Inselspital University Hospital Bern
Ubicacion Paises

Switzerland

Fecha de verificación

May 2020

Fiesta responsable

Tipo: Sponsor

Tiene acceso ampliado No
Condición Examinar
Acrónimo DEHYD
Información de diseño del estudio

Modelo de observación: Cohort

Perspectiva de tiempo: Prospective

Fuente: ClinicalTrials.gov