Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion

Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion: a Randomized Controlled Trial

Patrocinadores

Patrocinador principal: Chang Gung Memorial Hospital

Fuente Chang Gung Memorial Hospital
Resumen breve

Background: Intrauterine adhesions are a difficult clinical problem for reproductive infertility. The most common cause is uterine cavity surgery and post-abortion (including abortion and spontaneous abortion). After the abortion, the uterine cavity adhesion, when is the key point, the literature is not much ink, early literature has mentioned that after the abortion, the uterus scraping action is scraped in four days and the uterine adhesion will be smaller than one to four weeks. Much more, it seems that the sooner the uterine adhesion factor is excluded, the more it can reduce uterine adhesion, but the uterine curettage itself is a risk factor for uterine adhesion. This early practice, the current clinical application, is not used, Instead, it is a hysteroscopy. Our past clinical observations, as soon as possible after the abortion, outpatient hysteroscopy, can find the tissue factors that may cause adhesion in the uterine cavity as soon as possible, and immediately remove it with an outpatient hysteroscope.

Objective: To verify the early outpatient hysteroscopy and reduce the occurrence of intrauterine adhesion after abortion.

Expected benefits to patients: Abortion is likely to cause intrauterine adhesions, which may further cause the incidence of reproductive infertility, should be involved before the formation of permanent injury, reduce the adhesion of the uterine cavity. Outpatient hysteroscopy is a simple and easy-to-use examination procedure that is painless and does not require anesthesia. Although it is invasive but has few complications, it is expected to reduce the occurrence of intrauterine adhesion after abortion.

Estado general Recruiting
Fecha de inicio December 2, 2019
Fecha de Terminación March 30, 2022
Fecha de finalización primaria September 30, 2021
Fase N/A
Tipo de estudio Interventional
Resultado primario
Medida Periodo de tiempo
Incidence rate of intrauterine adhesions 6 months later after induced abortion
Resultado secundario
Medida Periodo de tiempo
The American Fertility Society (AFS) intrauterine adhesion (IUA) score 6 months later after induced abortion
Menstrual cycle condition: Menstrual amount 6 months later after induced abortion
Menstrual cycle condition: Menstrual duration 6 months later after induced abortion
Menstrual cycle condition: Menstrual symptoms 6 months later after induced abortion
Sonography findings:endometrial thickness 6 months later after induced abortion
Sonography findings: morphology 6 months later after induced abortion
Fertility outcome 2 years later after induced abortion
Inscripción 150
Condición
Intervención

Tipo de intervención: Procedure

Nombre de intervención: Hysteroscopy

Descripción: outpatient hysteroscopy after the first menstrual cycle in the follicular phase (9-12 days).

Etiqueta de grupo de brazo: Intervention

Elegibilidad

Criterios:

Inclusion Criteria:

- female age 20 to 45 years-old

- undergo induced abortion

- desire future fertility

- agree with the trial and sign the consent form

Exclusion Criteria:

- previous intrauterine surgery

- previous intrauterine adhesion

- previous having over(and/or equal to) 3 times of induced abortion

- infection condition

Género: Female

Edad mínima: 20 Years

Edad máxima: 45 Years

Voluntarios Saludables: Accepts Healthy Volunteers

Contacto general

Apellido: Kuo-Chung Lan, PhD

Teléfono: +886-975056415

Email: [email protected]

Ubicación
Instalaciones: Estado: Contacto: Copia de seguridad de contactos: Chang Gung Memorial Hospital Kuo-Chung Lan, PhD +886-975056415 [email protected]
Ubicacion Paises

Taiwan

Fecha de verificación

October 2019

Fiesta responsable

Tipo: Sponsor

Palabras clave
Tiene acceso ampliado No
Condición Examinar
Número de brazos 2
Grupo de brazo

Etiqueta: Intervention

Tipo: Experimental

Etiqueta: Control

Tipo: No Intervention

Datos del paciente Undecided
Información de diseño del estudio

Asignación: Randomized

Modelo de intervención: Parallel Assignment

Propósito primario: Prevention

Enmascaramiento: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Fuente: ClinicalTrials.gov