Transcutaneous Spinal Cord Stimulation for Parkinson Disease

Transcutaneous Spinal Cord Stimulation for Freezing of Gait in Parkinson Disease

Patrocinadores

Patrocinador principal: University of Sao Paulo General Hospital

Fuente University of Sao Paulo General Hospital
Resumen breve

Spinal cord stimulation has been used to treat gait problems in Parkinson's disease, with positive results along some studies. The use of non-invasive stimulation can be an alternative to stimulate the spinal corn.

Descripción detallada

Spinal cord stimulation has been used to treat gait problems in Parkinson's disease, with positive results along some studies. The use of non-invasive stimulation can be an alternative to stimulate the spinal corn. In this pilot trial, the investigators recruit participants with Parkinson' disease and freezing of gait. The aim of the study is to explore the safety along the non-invasive magnetic thoracic spinal cord stimulation as well the effect on gait problems, especially freezing of gait, prospectively, in an open-label fashion.

Estado general Recruiting
Fecha de inicio October 15, 2019
Fecha de Terminación November 30, 2019
Fecha de finalización primaria November 15, 2019
Fase N/A
Tipo de estudio Interventional
Resultado primario
Medida Periodo de tiempo
Freezing of gait score One week
Resultado secundario
Medida Periodo de tiempo
Gait speed baseline, 1 week, 4 week
Freezing of gait questionnaire baseline, 1 week, 4 week
Safety of the intervention - urinary incontinence 1 week, 4 week
Safety of the intervention - lower limb strength. 1 week, 4 week
Inscripción 5
Condición
Intervención

Tipo de intervención: Procedure

Nombre de intervención: Transcutaneous spinal cord stimulation

Descripción: Theta burst stimulation at thoracic level (T5) over 2 minutes

Etiqueta de grupo de brazo: Intervention

Elegibilidad

Criterios:

Inclusion Criteria:

- diagnosis of advanced idiopathic Parkinson's disease

- significant freezing of gait despite optimized treatment with medications and rehabilitation program

Exclusion Criteria:

- psychiatric symptoms

- dementia

- cardiac pacemaker

Género: All

Basado en el género: Yes

Descripción de género: aged 18 years or higher

Edad mínima: 18 Years

Edad máxima: N/A

Voluntarios Saludables: No

Ubicación
Instalaciones: Estado: Contacto: University of São Paulo Rubens G Cury, MD 551126610000 [email protected]
Ubicacion Paises

Brazil

Fecha de verificación

November 2019

Fiesta responsable

Tipo: Principal Investigator

Afiliación del investigador: University of Sao Paulo General Hospital

Nombre completo del investigador: Rubens Gisbert Cury

Título del investigador: Principal investigator

Tiene acceso ampliado No
Condición Examinar
Número de brazos 1
Grupo de brazo

Etiqueta: Intervention

Tipo: Experimental

Descripción: Intervention: non-invasive spinal cord stimulation

Información de diseño del estudio

Asignación: N/A

Modelo de intervención: Single Group Assignment

Descripción del modelo de intervención: Pilot study

Propósito primario: Treatment

Enmascaramiento: None (Open Label)

Fuente: ClinicalTrials.gov