Intervention d'exercice Gerofit pour les personnes âgées atteintes de drépanocytose (étude SICKLE-FIT) (SICKLE-FIT)

Expérimental: Exercer

Chaque cohorte de 5 à 8 participants fera de l'exercice 3 jours par semaine pendant 12 semaines maximum. Les séances d'exercices seront virtuelles

Comportemental: Programme d'exercices Gerofit

L'intervention d'exercice télé-Gerofit a une formation axée sur le respect des directives d'activité physique et incorporant un entraînement cardiovasculaire, de force et d'équilibre. Les séances comprendront également une composante de pleine conscience, un échauffement, un retour au calme et des contrôles de sécurité. Les exercices sont personnalisés en fonction de l'état fonctionnel de chacun. L'intensité des exercices sera déterminée par les participants fournissant une évaluation de l'effort perçu (RPE) sur une échelle de 0 (facile) à 10 (très difficile) tout au long de la session. Les séances d'exercices initiales commenceront à faible intensité et augmenteront progressivement la durée et l'intensité pour permettre à chaque personne d'atteindre les niveaux d'exercice recommandés à son propre rythme. Les exercices se font virtuellement via Zoom. Chaque cohorte aura 5 à 8 participants. Le programme d'exercices sera optimisé après chaque cohorte avec des modifications basées sur les commentaires des participants et des experts en exercice.

Feasibility, as Measured by Number of Participants Completing at Least 50% of the Exercise Sessions

Safety, as Measured by Number of Participants With Moderate or Severe Adverse Events

Number of participants with one or more moderate or severe adverse events within 48 hours after each exercise session.

Acceptability, as Measured by the Number of Participants Reporting the Intervention as Acceptable

Acceptability of the exercise program was measured on a scale of 1-10, where 1= severe dislike and 10 = absolute enjoyment. Reported as the number of participants with scores of 8-10.

Percent of Participants With Clinically Meaningful Change in Mobility as Measured by Usual Gait Speed

Reported as the percent change in usual walking speed on a 4.57 meter (15 feet) walking course.

Percent of Participants With Clinically Meaningful Change in Balance as Measured by Timed Up and Go

Performance test of physical mobility. This measures the number of seconds it takes to stand up from a standard chair (46cm), walk a distance of 10 ft (3 meters), turn back to the chair, and sit down again.

Percent of Participants With Clinically Meaningful Change in Aerobic Endurance as Measured by Six-Minute Walk Test (6MWT)

Measure of aerobic endurance. The participant walks as fast and as safely as possible for 6 minutes with prompts given every minute. Distance traveled in 6 minutes is recorded.

Percent of Participants With Clinically Meaningful Change in Upper Body Strength as Measured by Grip Strength

Measure of upper body strength. Jamar hydraulic hand dynamometer (Jamar Technologies) was used to measure grip strength in triplicate for both hands while subject remains seated. The greatest value was used in analysis.

Percent of Participants With Clinically Meaningful Change in Lower Body Strength as Measured by 30-second Chair Stand

30-second chair stand is a measure lower body strength. The participant sits in a folding chair without arms with chair pressed against the wall and stands up and sits back down with arms across their chest as many times as possible in 30 seconds.

Percent of Participants With Improved Quality of Movement Measured by Functional Movement Screen

Includes deep squat and mobility test of upper and lower extremities. This is measure of squat quality/form.