Cannabidiol and Emotional Stimuli (CAS)

Inclusion Criteria:

• 18-35 years of age.
• 38 healthy volunteers (19 male, 19 female; age range 18-35 years)
• All participants recruited without regard to race, religion or ethnicity through posters, advertisements and word-of-mouth referrals.
• Candidates screened in accordance with our general screening protocol, approved by the IRB under Protocol #13681B, which includes a physical, EKG, psychiatric screening interview and detailed drug use history questionnaire.

Exclusion Criteria:

• Individuals with a medical condition contraindicating study participation, as determined by the study site physician.
• Individuals regularly using any medications aside from hormonal contraception in women.
• Individuals with a current (active in the past year) DSM-IV Axis I mood, anxiety, eating, or substance dependence disorder or a lifetime history of a psychotic disorder or mania.
• Women who are pregnant, nursing, or planning to become pregnant in the next 3 months
• Participants reporting a known or suspected allergy to cannabinoids.
• The self-report questionnaires the investigators use require fluency in English, and have not been translated and validated in other languages, thus individuals with less than a high-school education or those not fluent in English were excluded, as lack of English familiarity at a high school level may compromise our ability to interpret their self-reports.
• Individuals with a BMI below 19 or above 30, as this would change dosing requirements.
• Individuals who report using marijuana >100 times in their lifetime, to reduce variation in possible developed tolerance to CBD.