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Risk Factors and Prediction Score of ARDS After Cardiac Surgery

2021년 1월 28일 업데이트: Guangfa Zhu, Beijing Anzhen Hospital
Acute respiratory distress syndrome following cardiac surgery severely affects the prognosis of patients; the mortality is up to 40%. Although experience many years of research and exploration, the effective methods for the treatment of acute respiratory distress syndrome is still relatively limited at present, including lung protective mechanical ventilation respiratory support, fluid management, glucocorticoid and other integrated organ function maintenance measures. It is currently the research of acute respiratory distress syndrome aims at the early discovery and takes effective measures to prevent its occurrence, hoping to improve the prognosis of patients. According to risk factors is established through the analysis of lung injury score early warning system, the early identification of acute respiratory distress syndrome patients at high risk, before the occurrence of acute respiratory distress syndrome take corresponding preventive measures can effectively reduce the incidence rate and mortality. So far, domestic and foreign research on the establishment of acute respiratory distress syndrome scoring early warning system is less. Cardiac surgery has significant characteristics, type of operation, location, operation, intraoperative blood transfusion and oxygenation, postoperative factors, are likely to be the factors of acute respiratory distress syndrome. As far as investigators know, so far there are few specialized for acute respiratory distress syndrome predicting lung injury after cardiac surgery. This study will be completed after the implementation of individualized dynamic lung injury score evaluation of cardiac surgery patients, identification of high-risk acute respiratory distress syndrome patients, to assist clinicians in early decision, take preventive measures. This study will improve the prognosis of acute respiratory distress syndrome patients after cardiac surgery; it is of great significance to improve the level of intensive care after cardiac surgery.

연구 개요

연구 유형

관찰

등록 (실제)

1333

연락처 및 위치

이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.

연구 장소

    • Beijing
      • Beijing, Beijing, 중국, 100029
        • Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

  • 어린이
  • 성인
  • 고령자

건강한 자원 봉사자를 받아들입니다

아니

연구 대상 성별

모두

샘플링 방법

비확률 샘플

연구 인구

Patients of cardiac surgery in Beijing Anzhen hospital

설명

Inclusion Criteria:

  • Retrospective group: cardiac surgery patients accepted from Jan 2013 to Dec 2015
  • Prospective group: cardiac surgery patients accepted from 2017 January to December

Exclusion Criteria:

  • refused to participate in the study
  • age less than 18 years old
  • before operation performed mechanical ventilation
  • before operation underwent IABP treatment
  • before operation continuous renal replacement therapy
  • before operation undergoing in vitro membrane oxygenator treatment
  • before operation has the pulmonary imaging showed bilateral pulmonary diffuse exudation of interstitial pneumonia, pulmonary infection or respiratory failure
  • the major trauma, sepsis, aspiration, shock, acute heart failure
  • before operation diagnosed as malignant tumor
  • Incomplete data.

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

코호트 및 개입

그룹/코호트
개입 / 치료
ARDS
ARDS patients after cardiac surgery
This is a clinical observational study, no intervention was included.
non-ARDS
non-ARDS patients after cardiac surgery
This is a clinical observational study, no intervention was included.
propective group
patients of cardiac surgery including ARDS and non-ARDS patients
This is a clinical observational study, no intervention was included.

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
기간
The number of acute respiratory distress syndrome following cardiac surgery in Anzhen hospital during Jan 2013 to Dec 2015.
기간: up to 12months
up to 12months
The number of patients of cardiac surgery in Anzhen hospital during Jan 2013 to Dec 2015.
기간: up to 12months
up to 12months
The number of acute respiratory distress syndrome following cardiac surgery in Anzhen hospital during Jan 2017 to Dec 2017.
기간: up to 12months
up to 12months
The number of patients of cardiac surgery in Anzhen hospital during Jan 2017 to Dec 2017.
기간: up to 12months
up to 12months
The number of diabetic patients in ARDS group.
기간: up to 1 month
up to 1 month
The number of diabetic patients in non-ARDS group.
기간: up to 1 month
up to 1 month
The number of chronic obstructive pulmonary disease patients in ARDS group.
기간: up to 1 month
up to 1 month
The number of chronic obstructive pulmonary disease patients in non-ARDS group.
기간: up to 1 month
up to 1 month
The type of operation in ARDS group.
기간: up to 1 month
up to 1 month
The type of operation in non-ARDS group.
기간: up to 1 month
up to 1 month
The body mass index in ARDS group.
기간: up to 1 month
up to 1 month
The body mass index in non-ARDS group.
기간: up to 1 month
up to 1 month
The heart function in ARDS group before operation.
기간: up to 1 month
up to 1 month
The heart function in non-ARDS group before operation.
기간: up to 1 month
up to 1 month
The oxygenation in ARDS group before operation.
기간: up to 1 month
up to 1 month
The oxygenation in non-ARDS group before operation.
기간: up to 1 month
up to 1 month
The drug taken by patients in ARDS group.
기간: up to 1 month
up to 1 month
The drug taken by patients in non-ARDS group.
기간: up to 1 month
up to 1 month
The nutrition situation of patients in ARDS group.
기간: up to 1 month
up to 1 month
The nutrition situation of patients in non-ARDS group.
기간: up to 1 month
up to 1 month
The process of operation in ARDS group.
기간: up to 1 month
up to 1 month
The process of operation in non-ARDS group.
기간: up to 1 month
up to 1 month
The blood transfusion of patients during operation in ARDS group.
기간: up to 1 month
up to 1 month
The blood transfusion of patients during operation in non-ARDS group.
기간: up to 1 month
up to 1 month
The oxygenation of patients during operation in ARDS group.
기간: up to 1 month
up to 1 month
The oxygenation of patients during operation in non-ARDS group.
기간: up to 1 month
up to 1 month
The drug taken by patients after operation in ARDS group.
기간: up to 1 month
up to 1 month
The drug taken by patients after operation in non-ARDS group.
기간: up to 1 month
up to 1 month
The oxygenation of patients after operation in ARDS group.
기간: up to 1 month
up to 1 month
The oxygenation of patients after operation in non-ARDS group.
기간: up to 1 month
up to 1 month
The situation of mechanical ventilation of patients after operation in ARDS group.
기간: up to 1 month
up to 1 month
The situation of mechanical ventilation of patients after operation in non-ARDS group.
기간: up to 1 month
up to 1 month

2차 결과 측정

결과 측정
기간
The mortality of acute respiratory distress syndrome following cardiac surgery in Anzhen hospital .
기간: up to 1months
up to 1months
The morbidity of acute respiratory distress syndrome following cardiac surgery in Anzhen hospital .
기간: up to 1months
up to 1months

공동 작업자 및 조사자

여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

수사관

  • 연구 의자: Guangfa Zhu, Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases

간행물 및 유용한 링크

연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.

일반 간행물

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작 (실제)

2017년 7월 1일

기본 완료 (실제)

2017년 9월 30일

연구 완료 (실제)

2017년 9월 30일

연구 등록 날짜

최초 제출

2016년 4월 25일

QC 기준을 충족하는 최초 제출

2016년 4월 29일

처음 게시됨 (추정)

2016년 5월 3일

연구 기록 업데이트

마지막 업데이트 게시됨 (실제)

2021년 2월 1일

QC 기준을 충족하는 마지막 업데이트 제출

2021년 1월 28일

마지막으로 확인됨

2019년 12월 1일

추가 정보

이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .

no intervention에 대한 임상 시험

구독하다