Диетические вмешательства при псориатическом артрите (DIPSA)

Активный компаратор: Диета 1

Диета 1 будет сосредоточена на схеме питания и мониторинге типов продуктов, дополнительного питания и обеспечении нутритивной поддержки с диетологом.

Другой: Диета 1

Диета 1 будет сосредоточена на том, какие продукты употребляются в пищу, и на их влиянии на течение болезни.

Активный компаратор: Диета 2

Диета 2 будет сосредоточена на диетическом образце и контроле количества пищи, дополнительного питания и нутритивной поддержки с диетологом.

Другой: Диета 2

Эта диета ограничит количество энергии, потребляемой каждый день, и влияние на исходы болезни. Это будет определяться факторами, включая демографические данные субъекта (возраст, пол, вес, рост).

Без вмешательства: Диета 3

Диета 3 будет сосредоточена на здоровом питании и обеспечит пищевую поддержку с диетологом.

Change in Disease Activity in Psoriatic Arthritis (DAPSA)

Disease Activity in Psoriatic Arthritis (DAPSA) is a total of the 5 elements listed below to assess disease activity from both clinical and patient-reported data. The total score falls within a range to indicate level of disease activity: 0-4 = Remission (minimum); 5-14 = Low; 15-28 = Moderate; >28 = High Disease Activity. There is no theoretical upper limit to the DAPSA score.

Total DAPSA score = TJ (Tender Joints) + SJ (Swollen Joints) + CRP (C-reactive protein) + Activity + Pain

1. Tender Joints Count (0-68 joints)
2. Swollen Joints Count (0-66 joints)
3. CRP (mg/dl)

4. Patient's assessment of disease activity and pain:

   1. How active was your rheumatic disease on average during the last week? Scale of 1-10 (Not Active -Active)
   2. How would you describe the overall level of joint pain during the last week? Scale of 1-10 (None-Very Severe)

Метаболический профиль-вес

Изменения веса; Вес (кг; Вес и рост будут объединены, чтобы сообщить ИМТ в кг/м^2; Индекс массы тела (ИМТ) _ вес/ч²; Стандартные категории весового статуса, связанные с диапазонами ИМТ для взрослых, перечислены как;

Статус веса ИМТ:

Менее 18,5 Недостаточный вес 18,5–24,9 Нормальный или здоровый вес 25,0–29,9 Избыточный вес 30,0 и выше Ожирение

По состоянию на 19 ноября 2019 г., https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/index.html#Interpreted

Метаболический профиль – измерение талии

Измерение талии_см

Change in Disease Activity in Psoriatic Arthritis (DAPSA)

Disease Activity in Psoriatic Arthritis (DAPSA) is a total of the 5 elements listed below to assess disease activity from both clinical and patient-reported data. The total score falls within a range to indicate level of disease activity: 0-4 = Remission (minimum); 5-14 = Low; 15-28 = Moderate; >28 = High Disease Activity. There is no theoretical upper limit to the DAPSA score.

DAPSA = TJ (Tender Joints) + SJ (Swollen Joints) + CRP (C-reactive protein) + Activity + Pain

1. Tender Joints Count (0-68 joints)
2. Swollen Joints Count (0-66 joints)
3. CRP (mg/dl)

4. Patient's assessment of disease activity and pain:

   1. How active was your rheumatic disease on average during the last week? Scale of 1-10 (Not Active -Active)
   2. How would you describe the overall level of joint pain during the last week? Scale of 1-10 (None-Very Severe)

Patient Reported Outcomes-Psoriatic Arthritis Disease Impact

-Psoriatic Arthritis Disease Impact- Psoriatic Arthritis Impact of Disease (PSAID). The PsAID is a measure developed by the European League Against Rheumatism (EULAR) and is composed of domains selected by an international group of patients with psoriatic arthritis. The questionnaire uses a weighted scoring system (weights were derived by patient impression of importance) and has a range of 0-10. A lower score indicates lower impact of disease from the patient perspective, and a score of 4 is considered a patient acceptable symptom state.

Patient Reported Outcomes-Fatigue

-Fatigue- PROMIS (Patient-Reported Outcomes Measurement Information System) Fatigue (CAT) The PROMIS Fatigue scale assesses fatigue experience and impact of fatigue over 7 days. The instrument includes items on exhaustion and ability to function normally in physical, social, mental and family roles and activities. This instrument has good content validity and responsiveness in rheumatoid arthritis, a similar inflammatory arthritis. We will use the CAT (Computerized Adaptive Test) response instrument. PROMIS uses Item Response Theory (IRT) statistical model that links individual questions to a presumed underlying trait or concept of global health represented by all items in the scale; instruments are scored using item-level calibrations ("response pattern scoring") in an online tool (T-Score range 0-100, where 50 is the mean with a standard deviation of 10). Increasing score indicates higher level of fatigue.