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High-intensity Interval Exercise and Chocolate Milk on Blood Glucose and Cognition

9 augusti 2018 uppdaterad av: Nick Bellissimo, Ryerson University

The Effects of High-intensity Interval Exercise and Chocolate Milk on Glycemic Control and Cognitive Function in Children.

The purpose of this study is to determine the separate and combined effects of high-intensity interval exercise and chocolate milk on glycemic response, cognitive function, subjective appetite, and salivary cortisol among children aged 9-13 year old children.

Studieöversikt

Status

Avslutad

Betingelser

Intervention / Behandling

Detaljerad beskrivning

Twenty children 9-13 years of age will be recruited for this study. On four separate mornings, after a 10 hour overnight fast, each child will consume a standardized breakfast (including orange juice, a strawberry breakfast bar and a pear fruit cup) at home. Using a 2x2 factorial design, 2 hours after breakfast consumption, each participant will arrive in the lab (T=-20 min) and participate in high-intensity interval exercise or sit quietly for 20 min, followed by a treatment drink of chocolate milk or water (control) consumption in 10 min. During high-intensity interval exercise treatment, children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down. Blood glucose will be measured via finger-prick at baseline (-20 min), 10, 30, 60, and 90 min. Cognitive functions will be measured using a battery of cognitive tests which assess verbal declarative memory, working memory, and executive functioning, and will be measured at baseline, 10. 30. 60, and 90 min. Subjective appetite and emotions will be measured using a 100-mm visual analogue scale (VAS) at baseline, 10, 30, 60, and 90 min. Salivary cortisol will be assessed from saliva samples collected using the passive drool method, and will be collected at baseline, 10 and 30 min.

Studietyp

Interventionell

Inskrivning (Faktisk)

20

Fas

  • Inte tillämpbar

Kontakter och platser

Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.

Studieorter

  • Kanada
    • Ontario
      • Toronto, Ontario, Kanada, M5B 2K3
        • School of Nutrition, Ryerson University

Deltagandekriterier

Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.

Urvalskriterier

Åldrar som är berättigade till studier

9 år till 13 år (Barn)

Tar emot friska volontärer

Ja

Kön som är behöriga för studier

Allt

Beskrivning

Inclusion Criteria:

  • be between 9 and 13 years of age
  • be healthy, and have been born at term
  • not be taking any medications
  • not have allergies to dairy or gluten.

Exclusion Criteria:

  • Food sensitivities, allergies, or dietary restrictions
  • Health, learning, emotional, or behavioural problems
  • Receiving any medications
  • Non-habitual breakfast eater (<5 days/week)

Studieplan

Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.

Hur är studien utformad?

Designdetaljer

  • Primärt syfte: Förebyggande
  • Tilldelning: Randomiserad
  • Interventionsmodell: Crossover tilldelning
  • Maskning: Ingen (Open Label)

Vapen och interventioner

Deltagargrupp / Arm
Intervention / Behandling
Experimentell: Exercise and Chocolate Milk

Children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down.

Children will then drink 240mL of chocolate milk
Övrig: Exercise and Chocolate Milk
High intensity interval exercise Chocolate Milk
Experimentell: Exercise and Water

Children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down.

Children will then drink 240mL of water
Övrig: Exercise and Water
High intensity interval exercise Water
Experimentell: Sitting and Chocolate Milk
Children will quietly sit for 20 minutes Children will then drink 240mL of chocolate milk
Övrig: Sitting and Chocolate Milk
Sitting Chocolate Milk
Experimentell: Sitting and Water
Children will quietly sit for 20 minutes Children will then drink 240mL of water
Övrig: Sitting and Water
Sitting Water

Vad mäter studien?

Primära resultatmått

Resultatmått
Åtgärdsbeskrivning
Tidsram
Change from baseline Glycemic Response
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Blood samples will be collected via finger-prick method to assess glycemic response (blood glucose, mmol/L)
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline verbal declarative memory
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Cognitive function test of verbal declarative memory
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline working memory
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
The n-back test consists of 2 levels, 1-back and 2-back, where letters are presented on the screen one at a time. During the 1-back level, participants need to determine if the presented letter is the same as the one letter presented 1 before it or not (by selected 'match' or 'no match' on the side of the screen) and during 2-back need to do determine if it is the same letter as the one presented 2 letters prior.
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline executive functioning
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
The Stroop test consists of one word appearing on the screen written in either blue, red, yellow or green. There are 24 congruent trials where the presented word is the name of the colour it is written it (i.e. 'red' appearing in the colour red), 24 incongruent trials where the word written is a colour word different from the one it is written in (i.e. 'red' appearing in the colour green), and 10 neutral trials where non-colour words appear (i.e. 'tape' appearing in yellow). The participant is asked to tap the corresponding colour that the word is written in as quickly as possible.
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

Sekundära resultatmått

Resultatmått
Åtgärdsbeskrivning
Tidsram
Change from baseline salivary cortisol response
Tidsram: baseline (-20 min), and 10 and 30 min post-drink consumption
Saliva samples will be collected via passive drool method to assess salivary cortisol response (ug/dL)
baseline (-20 min), and 10 and 30 min post-drink consumption
Change form baseline Subjective Appetite
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess appetite
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline aggression
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess aggression
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline anger
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess anger
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline excitement
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess excitement
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline disappointment
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess disappointment
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline happiness
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess happiness
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline upset
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess upset
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change form baseline frustration
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess frustration
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline alertness
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess alertness
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline sadness
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess sadness
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline tension
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess tension
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline exhaustion
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess exhaustion
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
Change from baseline sleepiness
Tidsram: baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption
100-mm Visual Analogue Scales (VAS) will be used to assess sleepiness
baseline (-20 min), and 10, 30, 60, and 90 min post-drink consumption

Samarbetspartners och utredare

Det är här du hittar personer och organisationer som är involverade i denna studie.

Sponsor

Ryerson University

Utredare

  • Studierektor: Nick Bellissimo, PHD, School of Nutrition, Ryerson University

Publikationer och användbara länkar

Den som ansvarar för att lägga in information om studien tillhandahåller frivilligt dessa publikationer. Dessa kan handla om allt som har med studien att göra.

Allmänna publikationer

Studieavstämningsdatum

Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.

Studera stora datum

Studiestart (Faktisk)

8 juli 2017

Primärt slutförande (Faktisk)

31 december 2017

Avslutad studie (Faktisk)

31 maj 2018

Studieregistreringsdatum

Först inskickad

29 september 2017

Först inskickad som uppfyllde QC-kriterierna

6 oktober 2017

Första postat (Faktisk)

9 oktober 2017

Uppdateringar av studier

Senaste uppdatering publicerad (Faktisk)

10 augusti 2018

Senaste inskickade uppdateringen som uppfyllde QC-kriterierna

9 augusti 2018

Senast verifierad

1 augusti 2018

Mer information

Termer relaterade till denna studie

Nyckelord

Andra studie-ID-nummer

  • REB2017- 088

Plan för individuella deltagardata (IPD)

Planerar du att dela individuella deltagardata (IPD)?

NEJ

Läkemedels- och apparatinformation, studiedokument

Studerar en amerikansk FDA-reglerad läkemedelsprodukt

Nej

Studerar en amerikansk FDA-reglerad produktprodukt

Nej

Denna information hämtades direkt från webbplatsen clinicaltrials.gov utan några ändringar. Om du har några önskemål om att ändra, ta bort eller uppdatera dina studieuppgifter, vänligen kontakta register@clinicaltrials.gov. Så snart en ändring har implementerats på clinicaltrials.gov, kommer denna att uppdateras automatiskt även på vår webbplats .

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