A New Tool for Assessing Fatigue in Individuals With Advanced Cancer
2022年5月12日 更新者：University of Alberta
Development of a Rapid Assessment Tool for Fatigue in Palliative Care
Fatigue is a common problem in advanced cancer and palliative care.
The development of tools to measure fatigue, however, has been slowed by their inability to distinguish between fatigue and other related symptoms, such as tiredness.
Our work suggests that these distinctions are important because they serve as markers for stressors associated with advancing disease.
We have developed a tool that we believe will distinguish between these two states as well as exhaustion.
In this study we will conduct some initial tests of this tool in preparation for its use as an outcome indicator in future studies.
研究概览
详细说明
Based on a series of qualitative studies, our group is developing a new rapid fatigue assessment screening tool (rFAST) for use with individuals who have advanced cancer and are receiving care in either an active treatment or palliative setting.
Hypotheses:
- The three tools (tiredness, fatigue, and exhaustion) in the rFAST are each defined by the same six dimensions: decline in stamina, decline in cognition, decline in sleep quality, diminished social network, and increased emotional reactivity
- The five subscales of the tiredness, fatigue, and exhaustion scales are internally consistent.
- Tiredness, fatigue, and exhaustion are distinct states that are manifested by unique patterns of scores on their 6 subscales
- The mean POMS-Vsf scores of individuals who meet the definition of fatigue will be lower than the mean POMS-Vsf scores of individuals who meet the definition of tiredness and higher than the mean POMS-Vsf scores of individuals who meet the definition of exhaustion.
Objectives
- To examine the factor structure of the tiredness, fatigue, and exhaustion scales of the rFAST.
- To examine the internal consistency of the 5 subscales within the tired, fatigue, and exhaustion scales.
- To compare actual rFAST scale scores to hypothesized scale profiles for tiredness, fatigue, and exhaustion.
研究类型
观察性的
注册 (实际的)
228
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
Alberta
-
Edmonton、Alberta、加拿大、T6G 2T4
- Faculty of Nursing, University of Alberta
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 及以上 (成人、年长者)
接受健康志愿者
不
有资格学习的性别
全部
取样方法
非概率样本
研究人群
Individuals with advanced cancer
描述
Inclusion Criteria:
- Patients with advanced cancer currently receiving treatment for either hematologic or lung cancer at the Jewish General Hospital in Montreal, or patients with advanced cancer currently receiving care through the Alberta Cancer Board (Cross Cancer Institute or Tom Baker Cancer Centre), or the palliative care programs associated with the regional health authority in Edmonton, Alberta who are at least 18 years old, able to read and write English, have a Folstein Mini Mental Status Exam score of at least 22.
Exclusion Criteria:
- Patients unable to give informed consent in English.
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
ACI Instrument
228 individuals completed the ACI instrument and other tools
|
Following ethics approval, 17 experts in symptom management assisted with content validation during the pilot phase.
In the main study, participants complete the FACT-F, the POMS-Vsf, and the ACI Instrument.
A research assistant collected demographic information and assigned an ECOG score.
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
ACI score
大体时间：day 1
|
Adaptive Capacity Index Score
|
day 1
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Karin L Olson, Ph.D.、University of Alberta
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始
2005年10月1日
初级完成 (实际的)
2007年10月1日
研究完成 (实际的)
2010年10月1日
研究注册日期
首次提交
2007年1月26日
首先提交符合 QC 标准的
2007年1月26日
首次发布 (估计)
2007年1月30日
研究记录更新
最后更新发布 (实际的)
2022年5月18日
上次提交的符合 QC 标准的更新
2022年5月12日
最后验证
2020年3月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
ACI instrument的临床试验
-
AC Immune SAWorldwide Clinical Trials招聘中阿尔茨海默氏病 | 前驱阿尔茨海默病 | 淀粉样斑块 | Β-淀粉样蛋白 | 唐氏综合症中的阿尔茨海默病美国, 西班牙, 英国
-
Yan JinXijing Hospital; Tang-Du Hospital未知
-
Centre Hospitalier Universitaire VaudoisLee Ann LAURENT APPLEGATE; Virginie PHILIPPE尚未招聘
-
AC Immune SAICON Clinical Research招聘中
-
AC Immune SANational Institute on Aging (NIA); Alzheimer's Disease Cooperative Study (ADCS); LuMind IDSC Foundation完全的
-
AC Immune SAJanssen Research & Development, LLC完全的脑部疾病 | 中枢神经系统疾病 | 认知障碍 | 失智 | Tau蛋白病 | 轻度认知障碍 | 阿尔茨海默氏病英国, 芬兰, 荷兰, 瑞典
-
AcuFocus, Inc.完全的