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二磷酸腺苷 (ADP) 受体抑制剂治疗:急性冠状动脉综合征后治疗模式和事件的纵向评估 (TRANSLATE-ACS)

2015年12月22日 更新者:Eli Lilly and Company

TRANSLATE-ACS 研究:ADP 受体抑制剂治疗:急性冠状动脉综合征后治疗模式和事件的纵向评估

ADP 受体抑制剂治疗:急性冠状动脉综合征后治疗模式和事件的纵向评估 (TRANSLATE-ACS) 研究是一项前瞻性、观察性纵向研究,旨在评估现实世界中普拉格雷和其他 ADP 受体抑制剂疗法在心肌梗死中的有效性和用途(MI) 参与者在指数住院期间接受了经皮冠状动脉介入治疗 (PCI)。 参与者管理和治疗决定由护理团队根据常规临床实践自行决定。 将在美国约 350 个地点招募约 17,000 名参与者。 将对大约 15,650 名参与者进行为期 15 个月的随访。

TRANSLATE-ACS 将补充随机对照临床试验和当前登记的结果,以解决通过 PCI 管理并开始 ADP 受体抑制剂治疗的 MI 参与者的真实世界治疗模式和临床结果。 除了确定普拉格雷与其他 ADP 受体抑制剂相比的有效性外,该研究还将确定与初始 ADP 受体抑制剂选择和纵向使用模式相关的因素,评估安全性,并描述和比较与 ADP 受体抑制剂相关的资源使用和医疗成本ADP 受体抑制剂。 此外,这项研究将生成从住院患者到门诊患者的连续信息,以提供目前新型 ADP 受体抑制剂无法获得的参与者治疗和结果的全面信息。

研究概览

地位

完全的

研究类型

观察性的

注册 (实际的)

12227

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

      • Rio Piedras、波多黎各、00924
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    • Alabama
      • Birmingham、Alabama、美国、35233
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      • Mobile、Alabama、美国、36617
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    • Alaska
      • Anchorage、Alaska、美国、99508
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      • Fayetteville、Alaska、美国、72703
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    • Arizona
      • Gilbert、Arizona、美国、85297
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      • Scottsdale、Arizona、美国、85258
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      • Tucson、Arizona、美国、85723
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    • Arkansas
      • Fort Smith、Arkansas、美国、72901
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      • Little Rock、Arkansas、美国、72205
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      • Rogers、Arkansas、美国、72758
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    • California
      • Berkeley、California、美国、94705
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      • Loma Linda、California、美国、92354
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      • Newport Beach、California、美国、92663
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      • Northridge、California、美国、91325
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      • Roseville、California、美国、95661
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      • Sacramento、California、美国、95819
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      • Salinas、California、美国、93901
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      • Santa Barbara、California、美国、93105
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      • Stockton、California、美国、95204
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      • Thousand Oaks、California、美国、91360
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      • Torrance、California、美国、90505
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    • Colorado
      • Aurora、Colorado、美国、80045
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      • Parker、Colorado、美国、80138
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    • Connecticut
      • Bridgeport、Connecticut、美国、06610
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      • Danbury、Connecticut、美国、06810
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      • Farmington、Connecticut、美国、06030
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      • Hartford、Connecticut、美国、06102
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    • Delaware
      • Newark、Delaware、美国、19718
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    • District of Columbia
      • Washington、District of Columbia、美国、20010
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    • Florida
      • Atlantis、Florida、美国、33462
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      • Brandon、Florida、美国、33511
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      • Ft Lauderdale、Florida、美国、33308
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      • Gainesville、Florida、美国、32608
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      • Hudson、Florida、美国、34667
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      • Jacksonville、Florida、美国、32209
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      • Lakeland、Florida、美国、33805
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      • Melbourne、Florida、美国、32901
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      • Miami Beach、Florida、美国、33140
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      • Ocala、Florida、美国、34471
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      • Orlando、Florida、美国、32806
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      • Stuart、Florida、美国、34996
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      • Tampa、Florida、美国、33613
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      • Vero Beach、Florida、美国、32960
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      • Wellington、Florida、美国、33449
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      • Winter Haven、Florida、美国、33881
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    • Georgia
      • Columbus、Georgia、美国、31904
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      • Marietta、Georgia、美国、30060
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      • Riverdale、Georgia、美国、30274
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    • Hawaii
      • Honolulu、Hawaii、美国、96813
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    • Illinois
      • Carbondale、Illinois、美国、62901
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      • Chicago、Illinois、美国、60625
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      • Geneva、Illinois、美国、60134
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      • Hoffman Estates、Illinois、美国、60169
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      • Joliet、Illinois、美国、60435
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      • Oak Lawn、Illinois、美国、60453
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      • Peoria、Illinois、美国、61614
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      • Rock Island、Illinois、美国、61201
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      • Rockford、Illinois、美国、61107
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      • Urbana、Illinois、美国、61801
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    • Indiana
      • Elkhart、Indiana、美国、46514
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      • Ft Wayne、Indiana、美国、46805
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      • Hammond、Indiana、美国、46320
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      • Indianapolis、Indiana、美国、46250
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      • Lafayette、Indiana、美国、47905
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      • Muncie、Indiana、美国、47303
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    • Iowa
      • Davenport、Iowa、美国、52803
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    • Kansas
      • Kansas City、Kansas、美国、66160
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      • Overland Park、Kansas、美国、66209
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      • Topeka、Kansas、美国、66604
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      • Wichita、Kansas、美国、67220
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    • Kentucky
      • Crestview Hills、Kentucky、美国、41017
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      • Lexington、Kentucky、美国、40504
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      • Owensboro、Kentucky、美国、42303
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    • Louisiana
      • Alexandria、Louisiana、美国、71301
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    • Maine
      • Lewiston、Maine、美国、04240
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    • Maryland
      • Annapolis、Maryland、美国、21401
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      • Baltimore、Maryland、美国、21215
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      • Cumberland、Maryland、美国、21502
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      • Hagerstown、Maryland、美国、21740
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      • Salisbury、Maryland、美国、21804
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      • Takoma Park、Maryland、美国、20912
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    • Massachusetts
      • Worcester、Massachusetts、美国、01606
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    • Michigan
      • Ann Arbor、Michigan、美国、48109
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Bay City、Michigan、美国、48708
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Dearborn、Michigan、美国、48124
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Detroit、Michigan、美国、48202
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Flint、Michigan、美国、48532
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Grand Blanc、Michigan、美国、48439
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Marquette、Michigan、美国、49855
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Mount Clemens、Michigan、美国、48043
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Saginaw、Michigan、美国、48602
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Southfield、Michigan、美国、48075
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • St. Joseph、Michigan、美国、49085
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Troy、Michigan、美国、48085
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Warren、Michigan、美国、48093
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Wyoming、Michigan、美国、49519
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Minnesota
      • Coon Rapids、Minnesota、美国、55433
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Duluth、Minnesota、美国、55805
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Edina、Minnesota、美国、55435
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Minneapolis、Minnesota、美国、55455
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • St Cloud、Minnesota、美国、56303
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Missouri
      • Columbia、Missouri、美国、65212
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Joplin、Missouri、美国、64804
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Kansas City、Missouri、美国、64114
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • North Kansas City、Missouri、美国、64116
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Springfield、Missouri、美国、65804
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • St Louis、Missouri、美国、63141
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Montana
      • Bozeman、Montana、美国、59715
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Kalispell、Montana、美国、59901
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Nebraska
      • Omaha、Nebraska、美国、68198
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Nevada
      • Las Vegas、Nevada、美国、89102
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Reno、Nevada、美国、89503
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • New Hampshire
      • Nashua、New Hampshire、美国、03060
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • New Jersey
      • Bridgewater、New Jersey、美国、08807
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Cherry Hill、New Jersey、美国、08034
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • New Brunswick、New Jersey、美国、08901
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Newark、New Jersey、美国、07055
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Ridgewood、New Jersey、美国、07450
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Summit、New Jersey、美国、07902
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • New Mexico
      • Albuquerque、New Mexico、美国、87131
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • New York
      • Brooklyn、New York、美国、11215
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Elmira、New York、美国、14905
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Johnson City、New York、美国、13790
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • New York、New York、美国、10075
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Stony Brook、New York、美国、11794
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Utica、New York、美国、13501
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Valhalla、New York、美国、10595
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • North Carolina
      • Chapel Hill、North Carolina、美国、27599
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Lumberton、North Carolina、美国、28358
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Raleigh、North Carolina、美国、27609
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Wilmington、North Carolina、美国、28402
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Winston-Salem、North Carolina、美国、27157
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Ohio
      • Canton、Ohio、美国、44710
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Cincinnati、Ohio、美国、45267
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Kettering、Ohio、美国、45429
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Middleburg Heights、Ohio、美国、44130
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Toledo、Ohio、美国、43615
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Youngstown、Ohio、美国、44501
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Oklahoma
      • Oklahoma City、Oklahoma、美国、73112
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Oregon
      • Bend、Oregon、美国、97701
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Portland、Oregon、美国、97225
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Tualatin、Oregon、美国、97062
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Pennsylvania
      • Abington、Pennsylvania、美国、19001
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Allentown、Pennsylvania、美国、18104
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Bryn Mawr、Pennsylvania、美国、19010
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Camp Hill、Pennsylvania、美国、17011
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Danville、Pennsylvania、美国、17822
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Darby、Pennsylvania、美国、19023
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Greensburg、Pennsylvania、美国、15601
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Harrisburg、Pennsylvania、美国、17111
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Hershey、Pennsylvania、美国、17033
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Johnstown、Pennsylvania、美国、15905
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Lancaster、Pennsylvania、美国、17602
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Langhorne、Pennsylvania、美国、19047
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Philadelphia、Pennsylvania、美国、19140
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Pittsburgh、Pennsylvania、美国、15240
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Sayre、Pennsylvania、美国、18840
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Uniontown、Pennsylvania、美国、15401
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • South Carolina
      • Anderson、South Carolina、美国、29621
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Charleston、South Carolina、美国、29485
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Columbia、South Carolina、美国、29203
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Tennessee
      • Memphis、Tennessee、美国、38120
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Nashville、Tennessee、美国、37205
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Texas
      • Dallas、Texas、美国、75216
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Decatur、Texas、美国、76234
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Grapevine、Texas、美国、76051
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Houston、Texas、美国、77030
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Round Rock、Texas、美国、78665
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Temple、Texas、美国、76508
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Virginia
      • Charlottesville、Virginia、美国、22908
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Chesapeake、Virginia、美国、23320
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Danville、Virginia、美国、24541
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Newport News、Virginia、美国、23601
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Norfolk、Virginia、美国、23507
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Richmond、Virginia、美国、23320
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Roanoke、Virginia、美国、24018
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Virginia Beach、Virginia、美国、23454
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Winchester、Virginia、美国、22601
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Washington
      • Bellevue、Washington、美国、98004
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Everett、Washington、美国、98201
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • West Virginia
      • Huntington、West Virginia、美国、25701
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    • Wisconsin
      • Green Bay、Wisconsin、美国、54308
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Milwaukee、Wisconsin、美国、53215
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Racine、Wisconsin、美国、53405
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
      • Waukesha、Wisconsin、美国、53188
        • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 及以上 (成人、年长者)

接受健康志愿者

有资格学习的性别

全部

取样方法

非概率样本

研究人群

接受经皮冠状动脉介入治疗 (PCI) 和 ADP 受体抑制剂治疗的急性心肌梗死 (MI) 入院或已经住院的参与者。

描述

纳入标准:

  • 大于或等于 18 岁
  • 被诊断为 NSTEMI 或 STEMI 在指数住院期间接受 PCI 治疗
  • 出院前开始(或继续)接受 ADP 受体抑制剂治疗
  • 完全知情并能够提供纵向随访和数据收集的书面同意

排除标准:

  • 在 MI 后的前 12 个月内同时参与一项指导选择研究性或批准的 ADP 受体抑制剂的研究

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

队列和干预

团体/队列
干预/治疗
ADP受体抑制剂治疗
因非 ST 段抬高心肌梗死 (NSTEMI) 或 ST 段抬高心肌梗死 (STEMI) 而接受经皮冠状动脉介入治疗 (PCI) 并在指数住院期间接受 ADP 受体抑制剂治疗的参与者。
剂量方案由治疗医师确定。

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
发生主要不良心血管事件 (MACE) 的参与者百分比
大体时间:通过 12 个月的基线
MACE 被定义为全因死亡、心肌梗死 (MI)、中风或计划外冠状动脉血运重建的复合。 在药物转换或停药后超过 7 天发生的事件被排除在分析之外。 呈现了观察到的(未调整的)MACE 参与者百分比,以及针对基线队列差异调整的统计分析。 参与者百分比 =(12 个月内发生事件的参与者人数/接受治疗的参与者人数)* 100。
通过 12 个月的基线
与入组时初始二磷酸腺苷 (ADP) 受体抑制剂选择相关的因素
大体时间:第 0 天(研究注册)
因素是药物洗脱支架 (DES) 与裸金属支架 (BMS) 放置、其他(无支架)与 BMS、STEMI、其他种族、24 小时内发生心源性休克、男性、欧洲生活质量调查问卷 - 5 维健康状况评分 (EQ-5D) - 美国 (US) 指数 =1 与 <1、已婚、糖尿病和其他与 BMS 安置。 EQ-5D US 指数是一种基于美国人口的参与者评定的、与健康相关的生活质量工具。 分数范围从 -0.11 到 1.0,其中 1.0 = 完美健康。
第 0 天(研究注册)
与入组时初始 ADP 受体抑制剂选择相关的因素:术前血红蛋白
大体时间:第 0 天(研究注册)
第 0 天(研究注册)
与入组时初始 ADP 受体抑制剂选择相关的因素:杜克冠状动脉疾病 (CAD) 指数
大体时间:第 0 天(研究注册)
Duke CAD 指数是经过验证的血管造影负担综合衡量指标,它分配了 1 到 100 的预后权重。 较高的分数表示较大的血管造影负担并且与较差的预后相关。
第 0 天(研究注册)

次要结果测量

结果测量
措施说明
大体时间
具有累积严重或中度出血事件的参与者的百分比
大体时间:基线、1、6、12 和 15 个月
出血事件是利用链激酶和组织纤溶酶原激活剂的全球应用治疗冠状动脉闭塞 (GUSTO) 出血定义收集的。 非冠状动脉旁路移植术 (CABG) 相关的 GUSTO 严重或危及生命的出血是指任何颅内出血 (ICH) 或任何导致需要治疗的严重血液动力学损害的出血事件。 非 CABG 相关的 GUSTO 中度出血是导致需要输血的任何出血事件,但不被视为 GUSTO 严重或危及生命的出血。 其他出血事件是致死性出血或 ICH,或任何非致死性手术相关出血事件导致 ≥ 4 个单位的红细胞输注。 呈现了观察到的(未调整的)出血事件参与者的百分比,以及针对基线队列差异调整的统计分析。 参与者百分比 =(有事件的参与者人数 / 接受治疗的参与者人数)* 100。
基线、1、6、12 和 15 个月
患有 MACE 并且没有短暂性脑缺血发作 (TIA)/中风病史、体重≥60 千克 (kg) 且年龄 <75 岁的参与者的百分比
大体时间:通过 12 个月的基线
MACE 被定义为全因死亡、心肌梗死、卒中或计划外冠状动脉血运重建的综合。 在药物转换或停药后超过 7 天发生的事件被排除在分析之外。 呈现了观察到的(未调整的)MACE 参与者百分比,以及针对基线队列差异调整的统计分析。 参与者百分比 =(有事件的参与者人数 / 接受治疗的参与者人数)* 100。
通过 12 个月的基线
在 1、6 和 15 个月内出现 MACE 的参与者百分比
大体时间:1、6 和 15 个月的基线
MACE 被定义为全因死亡、心肌梗死、卒中或计划外冠状动脉血运重建的综合。 在药物转换或停药后超过 7 天发生的事件被排除在分析之外。 呈现了观察到的(未调整的)参与者的 MACE 百分比。 Kaplan-Meier 分析用于估计发生 MACE 事件的参与者的百分比。
1、6 和 15 个月的基线
明确或可能发生支架内血栓形成 (ST) 事件的参与者百分比
大体时间:通过 15 个月的基线
学术研究联合会 (ARC) 标准用于定义 ST。 明确 ST 是血管造影或病理证实支架周围区域内部分或全部血栓性闭塞,并且至少符合以下附加标准之一:急性缺血症状;缺血性心电图改变;心脏生物标志物升高。 可能 ST 是支架植入后 30 天内任何无法解释的死亡;任何 MI,它与植入支架区域内记录的急性缺血有关,没有 ST 的血管造影确认,并且没有任何其他明显的原因。 在药物转换或停药后超过 7 天发生的事件被排除在分析之外。 呈现了具有 ST 事件的参与者的观察(未调整)百分比。 Kaplan-Meier 分析用于估计具有明确或可能的 ST 事件的参与者的百分比。
通过 15 个月的基线
资源使用模式、累计总医疗费用和成本效益
大体时间:15个月
15个月

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 研究主任:Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours EST)、Eli Lilly and Company

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2010年3月1日

初级完成 (实际的)

2014年1月1日

研究完成 (实际的)

2014年1月1日

研究注册日期

首次提交

2010年3月15日

首先提交符合 QC 标准的

2010年3月15日

首次发布 (估计)

2010年3月17日

研究记录更新

最后更新发布 (估计)

2016年1月29日

上次提交的符合 QC 标准的更新

2015年12月22日

最后验证

2015年12月1日

更多信息

与本研究相关的术语

其他研究编号

  • 12549
  • H7T-US-B007 (其他标识符:Eli Lilly and Company)

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

急性冠状动脉综合征的临床试验

  • Sanford Health
    National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research Foundation; Cornelia... 和其他合作者
    招聘中
    线粒体疾病 | 色素性视网膜炎 | 重症肌无力 | 嗜酸性胃肠炎 | 多系统萎缩 | 平滑肌肉瘤 | 脑白质营养不良 | 肛瘘 | 脊髓小脑性共济失调3型 | 弗里德赖希共济失调 | 肯尼迪病 | 莱姆病 | 噬血细胞性淋巴组织细胞增生症 | 脊髓小脑性共济失调1型 | 脊髓小脑性共济失调2型 | 脊髓小脑共济失调6型 | 威廉姆斯综合症 | 先天性巨结肠症 | 糖原贮积病 | 川崎病 | 短肠综合症 | 低磷血症 | Leber先天性黑蒙 | 口臭 | 贲门失弛缓症 | 多发性内分泌肿瘤 | 利综合症 | 艾迪生病 | 多发性内分泌肿瘤 2 型 | 硬皮病 | 多发性内分泌肿瘤 1 型 | 多发性内分泌肿瘤 2A 型 | 多发性内分泌肿瘤 2B 型 | 非典型溶血性尿毒症综合征 | 胆道闭锁 | 痉挛性共济失调 | WAGR综合症 | 无虹膜 | 短暂性失忆症 | 马尾综合症 | Refsum 疾病 | 复发性呼吸... 及其他条件
    美国, 澳大利亚

ADP受体抑制剂的临床试验

3
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