- ICH GCP
- Реестр клинических исследований США
- Клиническое испытание NCT01088503
Лечение ингибиторами рецепторов аденозиндифосфата (АДФ): лонгитюдная оценка моделей лечения и событий после острого коронарного синдрома (TRANSLATE-ACS)
Исследование TRANSLATE-ACS: лечение ингибиторами рецепторов АДФ: лонгитюдная оценка моделей лечения и событий после острого коронарного синдрома
Исследование «Лечение ингибиторами рецепторов АДФ: лонгитюдная оценка паттернов лечения и событий после острого коронарного синдрома» (TRANSLATE-ACS) — это проспективное обсервационное лонгитюдное исследование для оценки реальной эффективности и применения прасугрела и других ингибиторов рецепторов АДФ при инфаркте миокарда. (ИМ) участники, получавшие чрескожное коронарное вмешательство (ЧКВ) во время индексной госпитализации. Решения о ведении участников и лечении принимаются по усмотрению лечащей команды в соответствии с обычной клинической практикой. Приблизительно 17 000 участников будут зарегистрированы примерно в 350 центрах в Соединенных Штатах. Последующее наблюдение будет проводиться в течение 15 месяцев примерно у 15 650 участников.
TRANSLATE-ACS дополнит результаты как рандомизированных контролируемых клинических испытаний, так и текущих регистров, рассматривая реальные модели лечения и клинические результаты для участников ИМ, лечившихся с помощью ЧКВ и начавших терапию ингибиторами рецепторов АДФ. В дополнение к определению эффективности прасугрела по сравнению с другими ингибиторами рецепторов АДФ, в исследовании также будут определены факторы, связанные с первоначальным выбором ингибиторов рецепторов АДФ, и долгосрочные модели использования, оценка безопасности, а также описание и сравнение использования ресурсов и медицинских затрат, связанных с Ингибиторы рецепторов АДФ. Кроме того, это исследование будет генерировать континуум информации от стационарных до амбулаторных условий, чтобы предоставить всестороннюю картину лечения участников и результатов, недоступных в настоящее время для новых ингибиторов рецепторов АДФ.
Обзор исследования
Статус
Условия
Вмешательство/лечение
Тип исследования
Регистрация (Действительный)
Контакты и местонахождение
Места учебы
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Rio Piedras, Пуэрто-Рико, 00924
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Alabama
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Birmingham, Alabama, Соединенные Штаты, 35233
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Mobile, Alabama, Соединенные Штаты, 36617
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Alaska
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Anchorage, Alaska, Соединенные Штаты, 99508
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Fayetteville, Alaska, Соединенные Штаты, 72703
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Arizona
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Gilbert, Arizona, Соединенные Штаты, 85297
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Scottsdale, Arizona, Соединенные Штаты, 85258
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Tucson, Arizona, Соединенные Штаты, 85723
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Arkansas
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Fort Smith, Arkansas, Соединенные Штаты, 72901
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Little Rock, Arkansas, Соединенные Штаты, 72205
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Rogers, Arkansas, Соединенные Штаты, 72758
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California
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Berkeley, California, Соединенные Штаты, 94705
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Loma Linda, California, Соединенные Штаты, 92354
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Newport Beach, California, Соединенные Штаты, 92663
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Northridge, California, Соединенные Штаты, 91325
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Roseville, California, Соединенные Штаты, 95661
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Sacramento, California, Соединенные Штаты, 95819
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Salinas, California, Соединенные Штаты, 93901
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Santa Barbara, California, Соединенные Штаты, 93105
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Stockton, California, Соединенные Штаты, 95204
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Thousand Oaks, California, Соединенные Штаты, 91360
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Torrance, California, Соединенные Штаты, 90505
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Colorado
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Aurora, Colorado, Соединенные Штаты, 80045
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Parker, Colorado, Соединенные Штаты, 80138
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Connecticut
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Bridgeport, Connecticut, Соединенные Штаты, 06610
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Danbury, Connecticut, Соединенные Штаты, 06810
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Farmington, Connecticut, Соединенные Штаты, 06030
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Hartford, Connecticut, Соединенные Штаты, 06102
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Delaware
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Newark, Delaware, Соединенные Штаты, 19718
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District of Columbia
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Washington, District of Columbia, Соединенные Штаты, 20010
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Florida
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Atlantis, Florida, Соединенные Штаты, 33462
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Brandon, Florida, Соединенные Штаты, 33511
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Ft Lauderdale, Florida, Соединенные Штаты, 33308
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Gainesville, Florida, Соединенные Штаты, 32608
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Hudson, Florida, Соединенные Штаты, 34667
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Jacksonville, Florida, Соединенные Штаты, 32209
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Lakeland, Florida, Соединенные Штаты, 33805
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Melbourne, Florida, Соединенные Штаты, 32901
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Miami Beach, Florida, Соединенные Штаты, 33140
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Ocala, Florida, Соединенные Штаты, 34471
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Orlando, Florida, Соединенные Штаты, 32806
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Stuart, Florida, Соединенные Штаты, 34996
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Tampa, Florida, Соединенные Штаты, 33613
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Vero Beach, Florida, Соединенные Штаты, 32960
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Wellington, Florida, Соединенные Штаты, 33449
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Winter Haven, Florida, Соединенные Штаты, 33881
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Georgia
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Columbus, Georgia, Соединенные Штаты, 31904
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Marietta, Georgia, Соединенные Штаты, 30060
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Riverdale, Georgia, Соединенные Штаты, 30274
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Hawaii
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Honolulu, Hawaii, Соединенные Штаты, 96813
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Illinois
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Carbondale, Illinois, Соединенные Штаты, 62901
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Chicago, Illinois, Соединенные Штаты, 60625
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Geneva, Illinois, Соединенные Штаты, 60134
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Hoffman Estates, Illinois, Соединенные Штаты, 60169
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Joliet, Illinois, Соединенные Штаты, 60435
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Oak Lawn, Illinois, Соединенные Штаты, 60453
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Peoria, Illinois, Соединенные Штаты, 61614
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Rock Island, Illinois, Соединенные Штаты, 61201
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Rockford, Illinois, Соединенные Штаты, 61107
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Urbana, Illinois, Соединенные Штаты, 61801
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Indiana
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Elkhart, Indiana, Соединенные Штаты, 46514
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Ft Wayne, Indiana, Соединенные Штаты, 46805
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Hammond, Indiana, Соединенные Штаты, 46320
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Indianapolis, Indiana, Соединенные Штаты, 46250
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Lafayette, Indiana, Соединенные Штаты, 47905
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Muncie, Indiana, Соединенные Штаты, 47303
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Iowa
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Davenport, Iowa, Соединенные Штаты, 52803
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Kansas
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Kansas City, Kansas, Соединенные Штаты, 66160
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Overland Park, Kansas, Соединенные Штаты, 66209
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Topeka, Kansas, Соединенные Штаты, 66604
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Wichita, Kansas, Соединенные Штаты, 67220
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Kentucky
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Crestview Hills, Kentucky, Соединенные Штаты, 41017
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Lexington, Kentucky, Соединенные Штаты, 40504
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Owensboro, Kentucky, Соединенные Штаты, 42303
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Louisiana
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Alexandria, Louisiana, Соединенные Штаты, 71301
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Maine
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Lewiston, Maine, Соединенные Штаты, 04240
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Maryland
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Annapolis, Maryland, Соединенные Штаты, 21401
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Baltimore, Maryland, Соединенные Штаты, 21215
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Cumberland, Maryland, Соединенные Штаты, 21502
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Hagerstown, Maryland, Соединенные Штаты, 21740
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Salisbury, Maryland, Соединенные Штаты, 21804
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Takoma Park, Maryland, Соединенные Штаты, 20912
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Massachusetts
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Worcester, Massachusetts, Соединенные Штаты, 01606
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Michigan
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Ann Arbor, Michigan, Соединенные Штаты, 48109
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Bay City, Michigan, Соединенные Штаты, 48708
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Dearborn, Michigan, Соединенные Штаты, 48124
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Detroit, Michigan, Соединенные Штаты, 48202
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Flint, Michigan, Соединенные Штаты, 48532
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Grand Blanc, Michigan, Соединенные Штаты, 48439
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Marquette, Michigan, Соединенные Штаты, 49855
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Mount Clemens, Michigan, Соединенные Штаты, 48043
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Saginaw, Michigan, Соединенные Штаты, 48602
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Southfield, Michigan, Соединенные Штаты, 48075
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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St. Joseph, Michigan, Соединенные Штаты, 49085
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Troy, Michigan, Соединенные Штаты, 48085
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Warren, Michigan, Соединенные Штаты, 48093
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Wyoming, Michigan, Соединенные Штаты, 49519
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Minnesota
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Coon Rapids, Minnesota, Соединенные Штаты, 55433
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Duluth, Minnesota, Соединенные Штаты, 55805
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Edina, Minnesota, Соединенные Штаты, 55435
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Minneapolis, Minnesota, Соединенные Штаты, 55455
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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St Cloud, Minnesota, Соединенные Штаты, 56303
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Missouri
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Columbia, Missouri, Соединенные Штаты, 65212
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Joplin, Missouri, Соединенные Штаты, 64804
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Kansas City, Missouri, Соединенные Штаты, 64114
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
North Kansas City, Missouri, Соединенные Штаты, 64116
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Springfield, Missouri, Соединенные Штаты, 65804
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
St Louis, Missouri, Соединенные Штаты, 63141
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Montana
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Bozeman, Montana, Соединенные Штаты, 59715
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Kalispell, Montana, Соединенные Штаты, 59901
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Nebraska
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Omaha, Nebraska, Соединенные Штаты, 68198
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Nevada
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Las Vegas, Nevada, Соединенные Штаты, 89102
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Reno, Nevada, Соединенные Штаты, 89503
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
New Hampshire
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Nashua, New Hampshire, Соединенные Штаты, 03060
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
New Jersey
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Bridgewater, New Jersey, Соединенные Штаты, 08807
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Cherry Hill, New Jersey, Соединенные Штаты, 08034
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
New Brunswick, New Jersey, Соединенные Штаты, 08901
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Newark, New Jersey, Соединенные Штаты, 07055
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Ridgewood, New Jersey, Соединенные Штаты, 07450
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Summit, New Jersey, Соединенные Штаты, 07902
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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New Mexico
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Albuquerque, New Mexico, Соединенные Штаты, 87131
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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New York
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Brooklyn, New York, Соединенные Штаты, 11215
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Elmira, New York, Соединенные Штаты, 14905
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Johnson City, New York, Соединенные Штаты, 13790
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
New York, New York, Соединенные Штаты, 10075
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Stony Brook, New York, Соединенные Штаты, 11794
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Utica, New York, Соединенные Штаты, 13501
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Valhalla, New York, Соединенные Штаты, 10595
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
North Carolina
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Chapel Hill, North Carolina, Соединенные Штаты, 27599
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Lumberton, North Carolina, Соединенные Штаты, 28358
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Raleigh, North Carolina, Соединенные Штаты, 27609
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Wilmington, North Carolina, Соединенные Штаты, 28402
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Winston-Salem, North Carolina, Соединенные Штаты, 27157
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Ohio
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Canton, Ohio, Соединенные Штаты, 44710
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Cincinnati, Ohio, Соединенные Штаты, 45267
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Kettering, Ohio, Соединенные Штаты, 45429
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Middleburg Heights, Ohio, Соединенные Штаты, 44130
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Toledo, Ohio, Соединенные Штаты, 43615
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Youngstown, Ohio, Соединенные Штаты, 44501
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Oklahoma
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Oklahoma City, Oklahoma, Соединенные Штаты, 73112
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Oregon
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Bend, Oregon, Соединенные Штаты, 97701
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Portland, Oregon, Соединенные Штаты, 97225
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Tualatin, Oregon, Соединенные Штаты, 97062
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Pennsylvania
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Abington, Pennsylvania, Соединенные Штаты, 19001
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Allentown, Pennsylvania, Соединенные Штаты, 18104
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Bryn Mawr, Pennsylvania, Соединенные Штаты, 19010
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Camp Hill, Pennsylvania, Соединенные Штаты, 17011
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Danville, Pennsylvania, Соединенные Штаты, 17822
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Darby, Pennsylvania, Соединенные Штаты, 19023
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Greensburg, Pennsylvania, Соединенные Штаты, 15601
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Harrisburg, Pennsylvania, Соединенные Штаты, 17111
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Hershey, Pennsylvania, Соединенные Штаты, 17033
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Johnstown, Pennsylvania, Соединенные Штаты, 15905
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Lancaster, Pennsylvania, Соединенные Штаты, 17602
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Langhorne, Pennsylvania, Соединенные Штаты, 19047
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Philadelphia, Pennsylvania, Соединенные Штаты, 19140
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Pittsburgh, Pennsylvania, Соединенные Штаты, 15240
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Sayre, Pennsylvania, Соединенные Штаты, 18840
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Uniontown, Pennsylvania, Соединенные Штаты, 15401
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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South Carolina
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Anderson, South Carolina, Соединенные Штаты, 29621
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Charleston, South Carolina, Соединенные Штаты, 29485
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Columbia, South Carolina, Соединенные Штаты, 29203
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Tennessee
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Memphis, Tennessee, Соединенные Штаты, 38120
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Nashville, Tennessee, Соединенные Штаты, 37205
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Texas
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Dallas, Texas, Соединенные Штаты, 75216
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Decatur, Texas, Соединенные Штаты, 76234
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Grapevine, Texas, Соединенные Штаты, 76051
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Houston, Texas, Соединенные Штаты, 77030
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Round Rock, Texas, Соединенные Штаты, 78665
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Temple, Texas, Соединенные Штаты, 76508
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Virginia
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Charlottesville, Virginia, Соединенные Штаты, 22908
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Chesapeake, Virginia, Соединенные Штаты, 23320
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Danville, Virginia, Соединенные Штаты, 24541
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Newport News, Virginia, Соединенные Штаты, 23601
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Norfolk, Virginia, Соединенные Штаты, 23507
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Richmond, Virginia, Соединенные Штаты, 23320
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Roanoke, Virginia, Соединенные Штаты, 24018
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Virginia Beach, Virginia, Соединенные Штаты, 23454
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Winchester, Virginia, Соединенные Штаты, 22601
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Washington
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Bellevue, Washington, Соединенные Штаты, 98004
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Everett, Washington, Соединенные Штаты, 98201
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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West Virginia
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Huntington, West Virginia, Соединенные Штаты, 25701
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Wisconsin
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Green Bay, Wisconsin, Соединенные Штаты, 54308
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Milwaukee, Wisconsin, Соединенные Штаты, 53215
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Racine, Wisconsin, Соединенные Штаты, 53405
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Waukesha, Wisconsin, Соединенные Штаты, 53188
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Критерии участия
Критерии приемлемости
Возраст, подходящий для обучения
Принимает здоровых добровольцев
Полы, имеющие право на обучение
Метод выборки
Исследуемая популяция
Описание
Критерии включения:
- старше или равно 18 лет
- с диагнозом ИМбпST или ИМпST, пролеченным с помощью ЧКВ во время индексной госпитализации
- начало (или продолжение) терапии ингибиторами рецепторов АДФ перед выпиской
- полностью информированы и могут дать письменное согласие на лонгитюдное наблюдение и сбор данных
Критерий исключения:
- одновременное участие в научном исследовании, которое определяет выбор либо исследуемого, либо одобренного ингибитора рецептора АДФ в течение первых 12 месяцев после ИМ.
Учебный план
Как устроено исследование?
Детали дизайна
Когорты и вмешательства
Группа / когорта |
Вмешательство/лечение |
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Лечение ингибиторами рецепторов АДФ
Участники, госпитализированные по поводу инфаркта миокарда без подъема сегмента ST (NSTEMI) или инфаркта миокарда с подъемом сегмента ST (STEMI), подвергшиеся чрескожному коронарному вмешательству (PCI) и получавшие лечение ингибитором рецептора АДФ во время индексной госпитализации.
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Режим дозирования определяется лечащим врачом.
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Что измеряет исследование?
Первичные показатели результатов
Мера результата |
Мера Описание |
Временное ограничение |
---|---|---|
Процент участников с серьезными неблагоприятными сердечно-сосудистыми событиями (MACE)
Временное ограничение: Исходный уровень через 12 месяцев
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MACE определяется как комбинация смерти от всех причин, инфаркта миокарда (ИМ), инсульта или незапланированной коронарной реваскуляризации.
События, произошедшие более чем через 7 дней после замены или прекращения приема препарата, исключались из анализа.
Представлены наблюдаемые (нескорректированные) проценты участников с MACE, а также статистические анализы с поправкой на исходные когортные различия.
Процент участников = (количество участников с явлениями за 12 месяцев/количество участников, получавших лечение) * 100.
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Исходный уровень через 12 месяцев
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Факторы, связанные с исходным выбором ингибитора рецептора аденозиндифосфата (АДФ) при зачислении
Временное ограничение: День 0 (зачисление в учебу)
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Факторы: стент с лекарственным покрытием (СЛП) по сравнению с установкой стента из чистого металла (СГМ), другое (без стента) по сравнению со СГМ, ИМпST, другая раса, кардиогенный шок, возникший в течение 24 часов, мужчина, Европейский опросник качества жизни-5 Измерение Оценка состояния здоровья (EQ-5D) — индекс Соединенных Штатов (США) = 1 по сравнению с <1, состоящими в браке, диабетом и другими заболеваниями по сравнению с размещением BMS.
Американский индекс EQ-5D представляет собой оцениваемый участниками инструмент оценки качества жизни, связанный со здоровьем, основанный на населении США.
Оценки варьируются от -0,11 до 1,0, где 1,0 = отличное здоровье.
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День 0 (зачисление в учебу)
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Факторы, связанные с первоначальным выбором ингибиторов рецепторов АДФ при включении в исследование: гемоглобин перед процедурой
Временное ограничение: День 0 (зачисление в учебу)
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День 0 (зачисление в учебу)
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Факторы, связанные с первоначальным выбором ингибиторов рецепторов АДФ при зачислении: Индекс болезни коронарных артерий (ИБС) Дьюка
Временное ограничение: День 0 (зачисление в учебу)
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Индекс Duke CAD представляет собой проверенный составной показатель ангиографической нагрузки, который присваивает прогностические веса от 1 до 100.
Более высокие баллы указывают на большую ангиографическую нагрузку и связаны с более неблагоприятным прогнозом.
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День 0 (зачисление в учебу)
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Вторичные показатели результатов
Мера результата |
Мера Описание |
Временное ограничение |
---|---|---|
Процент участников с кумулятивными тяжелыми или умеренными кровотечениями
Временное ограничение: Исходный уровень, 1, 6, 12 и 15 месяцев
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Случаи кровотечения собирали с использованием определения кровотечения Глобального использования стрептокиназы и тканевого активатора плазминогена для окклюзированных коронарных артерий (GUSTO).
Тяжелое или опасное для жизни кровотечение GUSTO, связанное с неаортокоронарным шунтированием (АКШ), представляет собой любое внутричерепное кровоизлияние (ВЧК) ИЛИ любое кровотечение, приводящее к существенному гемодинамическому нарушению, требующему лечения.
Умеренное кровотечение по GUSTO, не связанное с АКШ, — это любое кровотечение, приводящее к необходимости переливания крови, которое не считается тяжелым или опасным для жизни кровотечением по GUSTO.
Дополнительными кровотечениями являются фатальные кровотечения или ICH, или любые несмертельные кровотечения, связанные с хирургическим вмешательством, приводящие к переливанию ≥4 единиц эритроцитарной массы.
Представлены наблюдаемые (нескорректированные) проценты участников с эпизодами кровотечения, а также статистические анализы, скорректированные на исходные когортные различия.
Процент участников = (количество участников с событиями / количество участников, пролеченных) * 100.
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Исходный уровень, 1, 6, 12 и 15 месяцев
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Процент участников с MACE, у которых в анамнезе не было транзиторной ишемической атаки (ТИА)/инсульта, вес ≥60 кг и возраст <75 лет
Временное ограничение: Исходный уровень через 12 месяцев
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MACE определяется как комбинация смерти от всех причин, инфаркта миокарда, инсульта или незапланированной коронарной реваскуляризации.
События, произошедшие более чем через 7 дней после замены или прекращения приема препарата, исключались из анализа.
Представлены наблюдаемые (нескорректированные) проценты участников с MACE, а также статистические анализы с поправкой на исходные когортные различия.
Процент участников = (количество участников с событиями / количество участников, пролеченных) * 100.
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Исходный уровень через 12 месяцев
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Процент участников с MACE в течение 1, 6 и 15 месяцев
Временное ограничение: Исходный уровень через 1, 6 и 15 месяцев
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MACE определяется как комбинация смерти от всех причин, инфаркта миокарда, инсульта или незапланированной коронарной реваскуляризации.
События, произошедшие более чем через 7 дней после замены или прекращения приема препарата, исключались из анализа.
Представлены наблюдаемые (нескорректированные) проценты участников с MACE.
Анализ Каплана-Мейера использовался для оценки процента участников с событием MACE.
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Исходный уровень через 1, 6 и 15 месяцев
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Процент участников с определенным или вероятным тромбозом стента (ST)
Временное ограничение: Исходный уровень через 15 месяцев
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Критерии Консорциума академических исследований (ARC) использовались для определения ST.
Определенный ST является ангиографическим или патологическим подтверждением частичной или полной тромботической окклюзии в области вокруг стента и по крайней мере 1 из следующих дополнительных критериев: симптомы острой ишемии; ишемические изменения электрокардиограммы; повышенные сердечные биомаркеры.
Вероятный ST — любая необъяснимая смерть в течение 30 дней после имплантации стента; любой ИМ, связанный с документально подтвержденной острой ишемией в области имплантированного стента без ангиографического подтверждения ST и при отсутствии какой-либо другой очевидной причины.
События, произошедшие более чем через 7 дней после замены или прекращения приема препарата, исключались из анализа.
Представлен наблюдаемый (нескорректированный) процент участников с событиями ST.
Анализ Каплана-Мейера использовался для оценки процента участников с определенным или вероятным событием ST.
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Исходный уровень через 15 месяцев
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Модели использования ресурсов, совокупные общие медицинские расходы и экономическая эффективность
Временное ограничение: 15 месяцев
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15 месяцев
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Соавторы и исследователи
Спонсор
Соавторы
Следователи
- Директор по исследованиям: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours EST), Eli Lilly and Company
Публикации и полезные ссылки
Общие публикации
- Rymer JA, Kaltenbach LA, Doll JA, Messenger JC, Peterson ED, Wang TY. Safety of Dual-Antiplatelet Therapy After Myocardial Infarction Among Patients With Chronic Kidney Disease. J Am Heart Assoc. 2019 May 21;8(10):e012236. doi: 10.1161/JAHA.119.012236.
- Warraich HJ, Kaltenbach LA, Fonarow GC, Peterson ED, Wang TY. Adverse Change in Employment Status After Acute Myocardial Infarction: Analysis From the TRANSLATE-ACS Study. Circ Cardiovasc Qual Outcomes. 2018 Jun;11(6):e004528. doi: 10.1161/CIRCOUTCOMES.117.004528.
- Fanaroff AC, Kaltenbach LA, Peterson ED, Akhter MW, Effron MB, Henry TD, Wang TY. Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study. J Am Heart Assoc. 2018 Feb 8;7(4):e007982. doi: 10.1161/JAHA.117.007982.
- Tisminetzky M, Wang TY, Gurwitz J, Kaltenbach LA, McManus D, Gore J, Peterson E, Goldberg RJ. Magnitude and Characteristics of Patients Who Survived an Acute Myocardial Infarction. J Am Heart Assoc. 2017 Sep 25;6(9):e006373. doi: 10.1161/JAHA.117.006373.
- Guimaraes PO, Krishnamoorthy A, Kaltenbach LA, Anstrom KJ, Effron MB, Mark DB, McCollam PL, Davidson-Ray L, Peterson ED, Wang TY. Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction : A Secondary Analysis of the TRANSLATE-ACS Study. JAMA Cardiol. 2017 Jul 1;2(7):750-757. doi: 10.1001/jamacardio.2017.1460.
- Hess CN, Kaltenbach LA, Doll JA, Cohen DJ, Peterson ED, Wang TY. Race and Sex Differences in Post-Myocardial Infarction Angina Frequency and Risk of 1-Year Unplanned Rehospitalization. Circulation. 2017 Feb 7;135(6):532-543. doi: 10.1161/CIRCULATIONAHA.116.024406.
- Jackson LR 2nd, Peterson ED, McCoy LA, Ju C, Zettler M, Baker BA, Messenger JC, Faries DE, Effron MB, Cohen DJ, Wang TY. Impact of Proton Pump Inhibitor Use on the Comparative Effectiveness and Safety of Prasugrel Versus Clopidogrel: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study. J Am Heart Assoc. 2016 Oct 21;5(10):e003824. doi: 10.1161/JAHA.116.003824.
- Fosbol EL, Ju C, Anstrom KJ, Zettler ME, Messenger JC, Waksman R, Effron MB, Baker BA, Cohen DJ, Peterson ED, Wang TY. Early Cessation of Adenosine Diphosphate Receptor Inhibitors Among Acute Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention: Insights From the TRANSLATE-ACS Study (Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome). Circ Cardiovasc Interv. 2016 Nov;9(11):e003602. doi: 10.1161/CIRCINTERVENTIONS.115.003602.
- Krishnamoorthy A, Peterson ED, Knight JD, Anstrom KJ, Effron MB, Zettler ME, Davidson-Ray L, Baker BA, McCollam PL, Mark DB, Wang TY. How Reliable are Patient-Reported Rehospitalizations? Implications for the Design of Future Practical Clinical Studies. J Am Heart Assoc. 2016 Jan 25;5(1):e002695. doi: 10.1161/JAHA.115.002695.
- Hess CN, Wang TY, McCoy LA, Messenger JC, Effron MB, Zettler ME, Henry TD, Peterson ED, Fonarow GC. Unplanned Inpatient and Observation Rehospitalizations After Acute Myocardial Infarction: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study. Circulation. 2016 Feb 2;133(5):493-501. doi: 10.1161/CIRCULATIONAHA.115.017001. Epub 2015 Dec 17.
- Wang TY, Henry TD, McCoy LA, Berger PB, Cohen DJ, Effron MB, Zettler M, Baker BA, Messenger JC, Peterson ED. Contemporary use of platelet function and pharmacogenomic testing among patients with acute myocardial infarction undergoing percutaneous coronary intervention in the United States. Am Heart J. 2015 Oct;170(4):706-14. doi: 10.1016/j.ahj.2015.06.021. Epub 2015 Jul 2.
- Mathews R, Wang TY, Honeycutt E, Henry TD, Zettler M, Chang M, Fonarow GC, Peterson ED; TRANSLATE-ACS Study Investigators. Persistence with secondary prevention medications after acute myocardial infarction: Insights from the TRANSLATE-ACS study. Am Heart J. 2015 Jul;170(1):62-9. doi: 10.1016/j.ahj.2015.03.019. Epub 2015 Apr 2.
- Mathews R, Peterson ED, Honeycutt E, Chin CT, Effron MB, Zettler M, Fonarow GC, Henry TD, Wang TY. Early Medication Nonadherence After Acute Myocardial Infarction: Insights into Actionable Opportunities From the TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) Study. Circ Cardiovasc Qual Outcomes. 2015 Jul;8(4):347-56. doi: 10.1161/CIRCOUTCOMES.114.001223. Epub 2015 Jun 2.
- Wang TY, Henry TD, Effron MB, Honeycutt E, Hess CN, Zettler ME, Cohen DJ, Baker BA, Berger PB, Anstrom KJ, Angiolillo DJ, Peterson ED; TRANSLATE-POPS Investigators. Cluster-randomized clinical trial examining the impact of platelet function testing on practice: the treatment with adenosine diphosphate receptor inhibitors: longitudinal assessment of treatment patterns and events after acute coronary syndrome prospective open label antiplatelet therapy study. Circ Cardiovasc Interv. 2015 Jun;8(6):e001712. doi: 10.1161/CIRCINTERVENTIONS.114.001712.
- Xian Y, Wang TY, McCoy LA, Effron MB, Henry TD, Bach RG, Zettler ME, Baker BA, Fonarow GC, Peterson ED. Association of Discharge Aspirin Dose With Outcomes After Acute Myocardial Infarction: Insights From the Treatment with ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) Study. Circulation. 2015 Jul 21;132(3):174-81. doi: 10.1161/CIRCULATIONAHA.114.014992. Epub 2015 May 20.
- Bagai A, Peterson ED, Honeycutt E, Effron MB, Cohen DJ, Goodman SG, Anstrom KJ, Gupta A, Messenger JC, Wang TY. In-hospital switching between adenosine diphosphate receptor inhibitors in patients with acute myocardial infarction treated with percutaneous coronary intervention: Insights into contemporary practice from the TRANSLATE-ACS study. Eur Heart J Acute Cardiovasc Care. 2015 Dec;4(6):499-508. doi: 10.1177/2048872614564082. Epub 2014 Dec 16.
- Hess CN, McCoy LA, Duggirala HJ, Tavris DR, O'Callaghan K, Douglas PS, Peterson ED, Wang TY. Sex-based differences in outcomes after percutaneous coronary intervention for acute myocardial infarction: a report from TRANSLATE-ACS. J Am Heart Assoc. 2014 Feb 7;3(1):e000523. doi: 10.1161/JAHA.113.000523.
- Wang TY, McCoy L, Henry TD, Effron MB, Messenger JC, Cohen DJ, Mark DB, Stone GW, Zettler M, Singh M, Fonarow GC, Peterson ED; TRANSLATE-ACS Study Investigators. Early post-discharge bleeding and antiplatelet therapy discontinuation among acute myocardial infarction patients treated with percutaneous coronary intervention. J Am Coll Cardiol. 2014 Apr 29;63(16):1700-2. doi: 10.1016/j.jacc.2013.12.012. Epub 2014 Jan 30. No abstract available.
- Chin CT, Wang TY, Anstrom KJ, Zhu B, Maa JF, Messenger JC, Ryan KA, Davidson-Ray L, Zettler M, Effron MB, Mark DB, Peterson ED. Treatment with adenosine diphosphate receptor inhibitors-longitudinal assessment of treatment patterns and events after acute coronary syndrome (TRANSLATE-ACS) study design: expanding the paradigm of longitudinal observational research. Am Heart J. 2011 Nov;162(5):844-51. doi: 10.1016/j.ahj.2011.08.021.
Даты записи исследования
Изучение основных дат
Начало исследования
Первичное завершение (Действительный)
Завершение исследования (Действительный)
Даты регистрации исследования
Первый отправленный
Впервые представлено, что соответствует критериям контроля качества
Первый опубликованный (Оценивать)
Обновления учебных записей
Последнее опубликованное обновление (Оценивать)
Последнее отправленное обновление, отвечающее критериям контроля качества
Последняя проверка
Дополнительная информация
Термины, связанные с этим исследованием
Дополнительные соответствующие термины MeSH
Другие идентификационные номера исследования
- 12549
- H7T-US-B007 (Другой идентификатор: Eli Lilly and Company)
Эта информация была получена непосредственно с веб-сайта clinicaltrials.gov без каких-либо изменений. Если у вас есть запросы на изменение, удаление или обновление сведений об исследовании, обращайтесь по адресу register@clinicaltrials.gov. Как только изменение будет реализовано на clinicaltrials.gov, оно будет автоматически обновлено и на нашем веб-сайте. .
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