Behandling med adenosindifosfat (ADP)-receptorhämmare: Longitudinell bedömning av behandlingsmönster och händelser efter akut koronarsyndrom (TRANSLATE-ACS)
22 december 2015 uppdaterad av: Eli Lilly and Company
TRANSLATE-ACS-studien: Behandling med ADP-receptorhämmare: Longitudinell bedömning av behandlingsmönster och händelser efter akut koronarsyndrom
Behandlingen med ADP-receptorhämmare: Longitudinell bedömning av behandlingsmönster och händelser efter akut koronarsyndrom (TRANSLATE-ACS)-studien är en prospektiv, observationell longitudinell studie för att utvärdera den verkliga effektiviteten och användningen av prasugrel och andra ADP-receptorhämmande behandlingar för hjärtinfarkt. (MI) deltagare som behandlades med perkutan kranskärlsintervention (PCI) under index sjukhusvistelsen. Beslut om hantering och behandling av deltagarna bestäms av vårdteamet per rutinmässig klinisk praxis. Cirka 17 000 deltagare kommer att registreras på cirka 350 platser i USA. Uppföljning kommer att genomföras under 15 månader hos cirka 15 650 deltagare.
TRANSLATE-ACS kommer att komplettera resultaten av både randomiserade kontrollerade kliniska prövningar och aktuella register för att ta itu med verkliga behandlingsmönster och kliniska resultat för MI-deltagare som hanteras med PCI och inleds med ADP-receptorhämmareterapi. Förutom att bestämma effektiviteten av prasugrel i jämförelse med andra ADP-receptorhämmare, kommer studien också att fastställa faktorer associerade med initialt urval av ADP-receptorhämmare och longitudinella användningsmönster, utvärdera säkerheten och beskriva och jämföra resursanvändning och medicinska kostnader förknippade med ADP-receptorhämmare. Dessutom kommer denna studie att generera en kontinuum av information från slutenvård till öppenvård för att ge en heltäckande bild av deltagares behandling och resultat som för närvarande inte är tillgängliga för nya ADP-receptorhämmare.
Studieöversikt
Status
Avslutad
Betingelser
Intervention / Behandling
Studietyp
Observationell
Inskrivning (Faktisk)
12227
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studieorter
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Alabama
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Birmingham, Alabama, Förenta staterna, 35233
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Mobile, Alabama, Förenta staterna, 36617
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Alaska
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Anchorage, Alaska, Förenta staterna, 99508
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Fayetteville, Alaska, Förenta staterna, 72703
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Arizona
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Gilbert, Arizona, Förenta staterna, 85297
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Scottsdale, Arizona, Förenta staterna, 85258
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Tucson, Arizona, Förenta staterna, 85723
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Arkansas
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Fort Smith, Arkansas, Förenta staterna, 72901
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Little Rock, Arkansas, Förenta staterna, 72205
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Rogers, Arkansas, Förenta staterna, 72758
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California
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Berkeley, California, Förenta staterna, 94705
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Loma Linda, California, Förenta staterna, 92354
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Newport Beach, California, Förenta staterna, 92663
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Northridge, California, Förenta staterna, 91325
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Roseville, California, Förenta staterna, 95661
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Sacramento, California, Förenta staterna, 95819
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Salinas, California, Förenta staterna, 93901
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Santa Barbara, California, Förenta staterna, 93105
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Stockton, California, Förenta staterna, 95204
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Thousand Oaks, California, Förenta staterna, 91360
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Torrance, California, Förenta staterna, 90505
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Colorado
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Aurora, Colorado, Förenta staterna, 80045
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Parker, Colorado, Förenta staterna, 80138
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Connecticut
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Bridgeport, Connecticut, Förenta staterna, 06610
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Danbury, Connecticut, Förenta staterna, 06810
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Farmington, Connecticut, Förenta staterna, 06030
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Hartford, Connecticut, Förenta staterna, 06102
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Delaware
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Newark, Delaware, Förenta staterna, 19718
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District of Columbia
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Washington, District of Columbia, Förenta staterna, 20010
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Florida
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Atlantis, Florida, Förenta staterna, 33462
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Brandon, Florida, Förenta staterna, 33511
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Ft Lauderdale, Florida, Förenta staterna, 33308
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Gainesville, Florida, Förenta staterna, 32608
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Hudson, Florida, Förenta staterna, 34667
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Jacksonville, Florida, Förenta staterna, 32209
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Lakeland, Florida, Förenta staterna, 33805
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Melbourne, Florida, Förenta staterna, 32901
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Miami Beach, Florida, Förenta staterna, 33140
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Ocala, Florida, Förenta staterna, 34471
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Orlando, Florida, Förenta staterna, 32806
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Stuart, Florida, Förenta staterna, 34996
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Tampa, Florida, Förenta staterna, 33613
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Vero Beach, Florida, Förenta staterna, 32960
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Wellington, Florida, Förenta staterna, 33449
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Winter Haven, Florida, Förenta staterna, 33881
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Georgia
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Columbus, Georgia, Förenta staterna, 31904
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Marietta, Georgia, Förenta staterna, 30060
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Riverdale, Georgia, Förenta staterna, 30274
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Hawaii
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Honolulu, Hawaii, Förenta staterna, 96813
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Illinois
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Carbondale, Illinois, Förenta staterna, 62901
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Chicago, Illinois, Förenta staterna, 60625
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Geneva, Illinois, Förenta staterna, 60134
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Hoffman Estates, Illinois, Förenta staterna, 60169
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Joliet, Illinois, Förenta staterna, 60435
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Oak Lawn, Illinois, Förenta staterna, 60453
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Peoria, Illinois, Förenta staterna, 61614
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Rock Island, Illinois, Förenta staterna, 61201
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Rockford, Illinois, Förenta staterna, 61107
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Urbana, Illinois, Förenta staterna, 61801
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Indiana
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Elkhart, Indiana, Förenta staterna, 46514
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Ft Wayne, Indiana, Förenta staterna, 46805
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Hammond, Indiana, Förenta staterna, 46320
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Indianapolis, Indiana, Förenta staterna, 46250
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Lafayette, Indiana, Förenta staterna, 47905
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Muncie, Indiana, Förenta staterna, 47303
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Iowa
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Davenport, Iowa, Förenta staterna, 52803
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Kansas
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Kansas City, Kansas, Förenta staterna, 66160
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Overland Park, Kansas, Förenta staterna, 66209
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Topeka, Kansas, Förenta staterna, 66604
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Wichita, Kansas, Förenta staterna, 67220
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Kentucky
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Crestview Hills, Kentucky, Förenta staterna, 41017
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Lexington, Kentucky, Förenta staterna, 40504
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Owensboro, Kentucky, Förenta staterna, 42303
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Louisiana
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Alexandria, Louisiana, Förenta staterna, 71301
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Maine
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Lewiston, Maine, Förenta staterna, 04240
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Maryland
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Annapolis, Maryland, Förenta staterna, 21401
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Baltimore, Maryland, Förenta staterna, 21215
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Cumberland, Maryland, Förenta staterna, 21502
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Hagerstown, Maryland, Förenta staterna, 21740
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Salisbury, Maryland, Förenta staterna, 21804
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Takoma Park, Maryland, Förenta staterna, 20912
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Massachusetts
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Worcester, Massachusetts, Förenta staterna, 01606
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Michigan
-
Ann Arbor, Michigan, Förenta staterna, 48109
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Bay City, Michigan, Förenta staterna, 48708
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Dearborn, Michigan, Förenta staterna, 48124
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Detroit, Michigan, Förenta staterna, 48202
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Flint, Michigan, Förenta staterna, 48532
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Grand Blanc, Michigan, Förenta staterna, 48439
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Marquette, Michigan, Förenta staterna, 49855
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Mount Clemens, Michigan, Förenta staterna, 48043
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Saginaw, Michigan, Förenta staterna, 48602
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Southfield, Michigan, Förenta staterna, 48075
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St. Joseph, Michigan, Förenta staterna, 49085
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Troy, Michigan, Förenta staterna, 48085
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Warren, Michigan, Förenta staterna, 48093
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Wyoming, Michigan, Förenta staterna, 49519
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Minnesota
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Coon Rapids, Minnesota, Förenta staterna, 55433
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Duluth, Minnesota, Förenta staterna, 55805
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-
Edina, Minnesota, Förenta staterna, 55435
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Minneapolis, Minnesota, Förenta staterna, 55455
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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St Cloud, Minnesota, Förenta staterna, 56303
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Missouri
-
Columbia, Missouri, Förenta staterna, 65212
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-
Joplin, Missouri, Förenta staterna, 64804
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Kansas City, Missouri, Förenta staterna, 64114
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
North Kansas City, Missouri, Förenta staterna, 64116
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Springfield, Missouri, Förenta staterna, 65804
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
St Louis, Missouri, Förenta staterna, 63141
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Montana
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Bozeman, Montana, Förenta staterna, 59715
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Kalispell, Montana, Förenta staterna, 59901
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Nebraska
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Omaha, Nebraska, Förenta staterna, 68198
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
Nevada
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Las Vegas, Nevada, Förenta staterna, 89102
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Reno, Nevada, Förenta staterna, 89503
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
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New Hampshire
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Nashua, New Hampshire, Förenta staterna, 03060
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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-
New Jersey
-
Bridgewater, New Jersey, Förenta staterna, 08807
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Cherry Hill, New Jersey, Förenta staterna, 08034
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
New Brunswick, New Jersey, Förenta staterna, 08901
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Newark, New Jersey, Förenta staterna, 07055
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Ridgewood, New Jersey, Förenta staterna, 07450
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Summit, New Jersey, Förenta staterna, 07902
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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New Mexico
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Albuquerque, New Mexico, Förenta staterna, 87131
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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New York
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Brooklyn, New York, Förenta staterna, 11215
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Elmira, New York, Förenta staterna, 14905
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Johnson City, New York, Förenta staterna, 13790
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
New York, New York, Förenta staterna, 10075
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Stony Brook, New York, Förenta staterna, 11794
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Utica, New York, Förenta staterna, 13501
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Valhalla, New York, Förenta staterna, 10595
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
North Carolina
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Chapel Hill, North Carolina, Förenta staterna, 27599
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Lumberton, North Carolina, Förenta staterna, 28358
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Raleigh, North Carolina, Förenta staterna, 27609
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Wilmington, North Carolina, Förenta staterna, 28402
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Winston-Salem, North Carolina, Förenta staterna, 27157
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Ohio
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Canton, Ohio, Förenta staterna, 44710
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Cincinnati, Ohio, Förenta staterna, 45267
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Kettering, Ohio, Förenta staterna, 45429
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Middleburg Heights, Ohio, Förenta staterna, 44130
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Toledo, Ohio, Förenta staterna, 43615
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Youngstown, Ohio, Förenta staterna, 44501
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Oklahoma
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Oklahoma City, Oklahoma, Förenta staterna, 73112
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Oregon
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Bend, Oregon, Förenta staterna, 97701
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Portland, Oregon, Förenta staterna, 97225
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Tualatin, Oregon, Förenta staterna, 97062
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Pennsylvania
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Abington, Pennsylvania, Förenta staterna, 19001
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Allentown, Pennsylvania, Förenta staterna, 18104
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Bryn Mawr, Pennsylvania, Förenta staterna, 19010
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Camp Hill, Pennsylvania, Förenta staterna, 17011
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Danville, Pennsylvania, Förenta staterna, 17822
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Darby, Pennsylvania, Förenta staterna, 19023
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-
Greensburg, Pennsylvania, Förenta staterna, 15601
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Harrisburg, Pennsylvania, Förenta staterna, 17111
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Hershey, Pennsylvania, Förenta staterna, 17033
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Johnstown, Pennsylvania, Förenta staterna, 15905
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Lancaster, Pennsylvania, Förenta staterna, 17602
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Langhorne, Pennsylvania, Förenta staterna, 19047
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Philadelphia, Pennsylvania, Förenta staterna, 19140
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Pittsburgh, Pennsylvania, Förenta staterna, 15240
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Sayre, Pennsylvania, Förenta staterna, 18840
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Uniontown, Pennsylvania, Förenta staterna, 15401
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
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South Carolina
-
Anderson, South Carolina, Förenta staterna, 29621
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Charleston, South Carolina, Förenta staterna, 29485
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Columbia, South Carolina, Förenta staterna, 29203
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Tennessee
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Memphis, Tennessee, Förenta staterna, 38120
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Nashville, Tennessee, Förenta staterna, 37205
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
-
Texas
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Dallas, Texas, Förenta staterna, 75216
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Decatur, Texas, Förenta staterna, 76234
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Grapevine, Texas, Förenta staterna, 76051
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
-
Houston, Texas, Förenta staterna, 77030
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Round Rock, Texas, Förenta staterna, 78665
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Temple, Texas, Förenta staterna, 76508
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Virginia
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Charlottesville, Virginia, Förenta staterna, 22908
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Chesapeake, Virginia, Förenta staterna, 23320
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Danville, Virginia, Förenta staterna, 24541
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Newport News, Virginia, Förenta staterna, 23601
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Norfolk, Virginia, Förenta staterna, 23507
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Richmond, Virginia, Förenta staterna, 23320
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Roanoke, Virginia, Förenta staterna, 24018
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Virginia Beach, Virginia, Förenta staterna, 23454
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Winchester, Virginia, Förenta staterna, 22601
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Washington
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Bellevue, Washington, Förenta staterna, 98004
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Everett, Washington, Förenta staterna, 98201
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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West Virginia
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Huntington, West Virginia, Förenta staterna, 25701
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Wisconsin
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Green Bay, Wisconsin, Förenta staterna, 54308
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Milwaukee, Wisconsin, Förenta staterna, 53215
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Racine, Wisconsin, Förenta staterna, 53405
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Waukesha, Wisconsin, Förenta staterna, 53188
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Rio Piedras, Puerto Rico, 00924
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
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Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
18 år och äldre (Vuxen, Äldre vuxen)
Tar emot friska volontärer
Nej
Kön som är behöriga för studier
Allt
Testmetod
Icke-sannolikhetsprov
Studera befolkning
Deltagare inlagda eller redan på sjukhus med akut hjärtinfarkt (MI) som behandlas med perkutan koronar intervention (PCI) och en ADP-receptorhämmare.
Beskrivning
Inklusionskriterier:
- äldre än eller lika med 18 år
- diagnostiserats med NSTEMI eller STEMI som behandlats med en PCI under index sjukhusvistelsen
- initierad (eller fortsatt) på ADP-receptorhämmarebehandling före utskrivning
- fullt informerad och kan ge skriftligt samtycke till longitudinell uppföljning och datainsamling
Exklusions kriterier:
- samtidigt delta i en forskningsstudie som styr valet av antingen en prövnings- eller godkänd ADP-receptorhämmare inom de första 12 månaderna efter MI
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
Kohorter och interventioner
Grupp / Kohort |
Intervention / Behandling |
|---|---|
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ADP-receptorhämmare behandling
Deltagare som togs in för hjärtinfarkt utan ST-höjning (NSTEMI) eller hjärtinfarkt med ST-höjning (STEMI) som genomgick perkutan kranskärlsintervention (PCI) och behandlades med en ADP-receptorhämmare under sjukhusvistelsen.
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Doseringsregim som bestäms av den behandlande läkaren.
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Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Andel deltagare med allvarliga kardiovaskulära händelser (MACE)
Tidsram: Baslinje till och med 12 månader
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MACE definieras som en sammansättning av dödsfall av alla orsaker, hjärtinfarkt (MI), stroke eller oplanerad koronar revaskularisering.
Händelser som inträffade mer än 7 dagar efter att medicinen byttes eller avbröts exkluderades från analysen.
Observerade (ojusterade) procentandelar av deltagare med MACE, liksom de statistiska analyserna justerade för baslinjekohortskillnader, presenteras.
Andel deltagare = (antal deltagare med evenemang under 12 månader/ antal behandlade deltagare) * 100.
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Baslinje till och med 12 månader
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Faktorer associerade med initialt val av adenosindifosfat (ADP) receptorhämmare vid inskrivning
Tidsram: Dag 0 (studieregistrering)
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Faktorer är läkemedelsavgivande stent (DES) vs. blottmetallstent (BMS) placering, annan (ingen stent) vs. BMS, STEMI, annan ras, kardiogen chock inträffade inom 24 timmar, män, European Quality of Life Questionnaire-5 Dimension Health State Score (EQ-5D) - United States (US) Index =1 vs. <1, gift, diabetes och annan vs. BMS-placering.
EQ-5D US-index är ett deltagareklassat, hälsorelaterat livskvalitetsinstrument baserat på USA:s befolkning.
Poäng varierar från -0,11 till 1,0 med 1,0 = perfekt hälsa.
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Dag 0 (studieregistrering)
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Faktorer associerade med initialt urval av ADP-receptorhämmare vid registrering: Hemoglobin före proceduren
Tidsram: Dag 0 (studieregistrering)
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Dag 0 (studieregistrering)
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Faktorer associerade med initialt urval av ADP-receptorhämmare vid registrering: Duke Coronary Artery Disease (CAD) Index
Tidsram: Dag 0 (studieregistrering)
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Duke CAD Index är ett validerat sammansatt mått på angiografisk belastning, som tilldelar prognostiska vikter 1 till 100.
Högre poäng indikerar större angiografisk börda och är associerade med sämre prognos.
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Dag 0 (studieregistrering)
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Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
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Andel deltagare med kumulativa svåra eller måttliga blödningar
Tidsram: Baslinje, 1, 6, 12 och 15 månader
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Blödningshändelser samlades in med användning av den globala användningen av streptokinas och vävnadsplasminogenaktivator för ockluderade kransartärer (GUSTO) definition av blödning.
Icke-koronarartär bypasstransplantation (CABG)-relaterad GUSTO allvarlig eller livshotande blödning är varje intrakraniell blödning (ICH) ELLER varje blödningshändelse som resulterar i betydande hemodynamisk kompromiss som kräver behandling.
Icke-CABG-relaterad GUSTO måttlig blödning är varje blödningshändelse som resulterar i behov av transfusion som inte anses vara en GUSTO allvarlig eller livshotande blödning.
Ytterligare blödningshändelser är dödlig blödning eller ICH, eller alla icke-dödliga kirurgiska blödningar som leder till ≥4 enheter av röda blodkroppar.
Observerade (ojusterade) procentandelar av deltagare med blödningshändelser, liksom de statistiska analyserna justerade för baslinjekohortskillnader, presenteras.
Andel deltagare = (antal deltagare med evenemang / antal behandlade deltagare) * 100.
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Baslinje, 1, 6, 12 och 15 månader
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Andel deltagare med MACE och som inte hade någon tidigare historia av transient ischemisk attack (TIA)/stroke, väger ≥60 kilogram (kg) och är <75 år gamla
Tidsram: Baslinje till och med 12 månader
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MACE definieras som en sammansättning av dödsfall av alla orsaker, MI, stroke eller oplanerad koronar revaskularisering.
Händelser som inträffade mer än 7 dagar efter att medicinen byttes eller avbröts exkluderades från analysen.
Observerade (ojusterade) procentandelar av deltagare med MACE, liksom de statistiska analyserna justerade för baslinjekohortskillnader, presenteras.
Andel deltagare = (antal deltagare med evenemang / antal behandlade deltagare) * 100.
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Baslinje till och med 12 månader
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Andel deltagare med MACE över 1, 6 och 15 månader
Tidsram: Baslinje genom 1, 6 och 15 månader
|
MACE definieras som en sammansättning av dödsfall av alla orsaker, MI, stroke eller oplanerad koronar revaskularisering.
Händelser som inträffade mer än 7 dagar efter att medicinen byttes eller avbröts exkluderades från analysen.
Observerade (ojusterade) procentandelar av deltagare med MACE presenteras.
Kaplan-Meier-analys användes för att uppskatta andelen deltagare med en MACE-händelse.
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Baslinje genom 1, 6 och 15 månader
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Andel deltagare med bestämda eller sannolika händelser med stenttrombos (ST).
Tidsram: Baslinje till och med 15 månader
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Kriterier för Academic Research Consortium (ARC) användes för att definiera ST.
Definitiv ST är angiografisk eller patologisk bekräftelse på partiell eller total trombotisk ocklusion inom peri-stentregionen, och minst ett av följande ytterligare kriterier: akuta ischemiska symtom; ischemiska elektrokardiogramförändringar; förhöjda hjärtbiomarkörer.
Sannolik ST är varje oförklarat dödsfall inom 30 dagar efter stentimplantation; varje hjärtinfarkt, som är relaterat till dokumenterad akut ischemi i den implanterade stentens territorium utan angiografisk bekräftelse av ST och i frånvaro av någon annan uppenbar orsak.
Händelser som inträffade mer än 7 dagar efter att medicinen byttes eller avbröts exkluderades från analysen.
Observerade (ojusterade) procentandelar av deltagare med ST-evenemang presenteras.
Kaplan-Meier-analys användes för att uppskatta andelen deltagare med en säker eller trolig ST-händelse.
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Baslinje till och med 15 månader
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Resursanvändningsmönster, kumulativa totala medicinska kostnader och kostnadseffektivitet
Tidsram: 15 månader
|
15 månader
|
Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Sponsor
Samarbetspartners
Utredare
- Studierektor: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours EST), Eli Lilly and Company
Publikationer och användbara länkar
Den som ansvarar för att lägga in information om studien tillhandahåller frivilligt dessa publikationer. Dessa kan handla om allt som har med studien att göra.
Allmänna publikationer
- Rymer JA, Kaltenbach LA, Doll JA, Messenger JC, Peterson ED, Wang TY. Safety of Dual-Antiplatelet Therapy After Myocardial Infarction Among Patients With Chronic Kidney Disease. J Am Heart Assoc. 2019 May 21;8(10):e012236. doi: 10.1161/JAHA.119.012236.
- Warraich HJ, Kaltenbach LA, Fonarow GC, Peterson ED, Wang TY. Adverse Change in Employment Status After Acute Myocardial Infarction: Analysis From the TRANSLATE-ACS Study. Circ Cardiovasc Qual Outcomes. 2018 Jun;11(6):e004528. doi: 10.1161/CIRCOUTCOMES.117.004528.
- Fanaroff AC, Kaltenbach LA, Peterson ED, Akhter MW, Effron MB, Henry TD, Wang TY. Antiplatelet Therapy Changes for Patients With Myocardial Infarction With Recurrent Ischemic Events: Insights Into Contemporary Practice From the TRANSLATE-ACS (Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome) Study. J Am Heart Assoc. 2018 Feb 8;7(4):e007982. doi: 10.1161/JAHA.117.007982.
- Tisminetzky M, Wang TY, Gurwitz J, Kaltenbach LA, McManus D, Gore J, Peterson E, Goldberg RJ. Magnitude and Characteristics of Patients Who Survived an Acute Myocardial Infarction. J Am Heart Assoc. 2017 Sep 25;6(9):e006373. doi: 10.1161/JAHA.117.006373.
- Guimaraes PO, Krishnamoorthy A, Kaltenbach LA, Anstrom KJ, Effron MB, Mark DB, McCollam PL, Davidson-Ray L, Peterson ED, Wang TY. Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction : A Secondary Analysis of the TRANSLATE-ACS Study. JAMA Cardiol. 2017 Jul 1;2(7):750-757. doi: 10.1001/jamacardio.2017.1460.
- Hess CN, Kaltenbach LA, Doll JA, Cohen DJ, Peterson ED, Wang TY. Race and Sex Differences in Post-Myocardial Infarction Angina Frequency and Risk of 1-Year Unplanned Rehospitalization. Circulation. 2017 Feb 7;135(6):532-543. doi: 10.1161/CIRCULATIONAHA.116.024406.
- Jackson LR 2nd, Peterson ED, McCoy LA, Ju C, Zettler M, Baker BA, Messenger JC, Faries DE, Effron MB, Cohen DJ, Wang TY. Impact of Proton Pump Inhibitor Use on the Comparative Effectiveness and Safety of Prasugrel Versus Clopidogrel: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study. J Am Heart Assoc. 2016 Oct 21;5(10):e003824. doi: 10.1161/JAHA.116.003824.
- Fosbol EL, Ju C, Anstrom KJ, Zettler ME, Messenger JC, Waksman R, Effron MB, Baker BA, Cohen DJ, Peterson ED, Wang TY. Early Cessation of Adenosine Diphosphate Receptor Inhibitors Among Acute Myocardial Infarction Patients Treated With Percutaneous Coronary Intervention: Insights From the TRANSLATE-ACS Study (Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome). Circ Cardiovasc Interv. 2016 Nov;9(11):e003602. doi: 10.1161/CIRCINTERVENTIONS.115.003602.
- Krishnamoorthy A, Peterson ED, Knight JD, Anstrom KJ, Effron MB, Zettler ME, Davidson-Ray L, Baker BA, McCollam PL, Mark DB, Wang TY. How Reliable are Patient-Reported Rehospitalizations? Implications for the Design of Future Practical Clinical Studies. J Am Heart Assoc. 2016 Jan 25;5(1):e002695. doi: 10.1161/JAHA.115.002695.
- Hess CN, Wang TY, McCoy LA, Messenger JC, Effron MB, Zettler ME, Henry TD, Peterson ED, Fonarow GC. Unplanned Inpatient and Observation Rehospitalizations After Acute Myocardial Infarction: Insights From the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) Study. Circulation. 2016 Feb 2;133(5):493-501. doi: 10.1161/CIRCULATIONAHA.115.017001. Epub 2015 Dec 17.
- Wang TY, Henry TD, McCoy LA, Berger PB, Cohen DJ, Effron MB, Zettler M, Baker BA, Messenger JC, Peterson ED. Contemporary use of platelet function and pharmacogenomic testing among patients with acute myocardial infarction undergoing percutaneous coronary intervention in the United States. Am Heart J. 2015 Oct;170(4):706-14. doi: 10.1016/j.ahj.2015.06.021. Epub 2015 Jul 2.
- Mathews R, Wang TY, Honeycutt E, Henry TD, Zettler M, Chang M, Fonarow GC, Peterson ED; TRANSLATE-ACS Study Investigators. Persistence with secondary prevention medications after acute myocardial infarction: Insights from the TRANSLATE-ACS study. Am Heart J. 2015 Jul;170(1):62-9. doi: 10.1016/j.ahj.2015.03.019. Epub 2015 Apr 2.
- Mathews R, Peterson ED, Honeycutt E, Chin CT, Effron MB, Zettler M, Fonarow GC, Henry TD, Wang TY. Early Medication Nonadherence After Acute Myocardial Infarction: Insights into Actionable Opportunities From the TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) Study. Circ Cardiovasc Qual Outcomes. 2015 Jul;8(4):347-56. doi: 10.1161/CIRCOUTCOMES.114.001223. Epub 2015 Jun 2.
- Wang TY, Henry TD, Effron MB, Honeycutt E, Hess CN, Zettler ME, Cohen DJ, Baker BA, Berger PB, Anstrom KJ, Angiolillo DJ, Peterson ED; TRANSLATE-POPS Investigators. Cluster-randomized clinical trial examining the impact of platelet function testing on practice: the treatment with adenosine diphosphate receptor inhibitors: longitudinal assessment of treatment patterns and events after acute coronary syndrome prospective open label antiplatelet therapy study. Circ Cardiovasc Interv. 2015 Jun;8(6):e001712. doi: 10.1161/CIRCINTERVENTIONS.114.001712.
- Xian Y, Wang TY, McCoy LA, Effron MB, Henry TD, Bach RG, Zettler ME, Baker BA, Fonarow GC, Peterson ED. Association of Discharge Aspirin Dose With Outcomes After Acute Myocardial Infarction: Insights From the Treatment with ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) Study. Circulation. 2015 Jul 21;132(3):174-81. doi: 10.1161/CIRCULATIONAHA.114.014992. Epub 2015 May 20.
- Bagai A, Peterson ED, Honeycutt E, Effron MB, Cohen DJ, Goodman SG, Anstrom KJ, Gupta A, Messenger JC, Wang TY. In-hospital switching between adenosine diphosphate receptor inhibitors in patients with acute myocardial infarction treated with percutaneous coronary intervention: Insights into contemporary practice from the TRANSLATE-ACS study. Eur Heart J Acute Cardiovasc Care. 2015 Dec;4(6):499-508. doi: 10.1177/2048872614564082. Epub 2014 Dec 16.
- Hess CN, McCoy LA, Duggirala HJ, Tavris DR, O'Callaghan K, Douglas PS, Peterson ED, Wang TY. Sex-based differences in outcomes after percutaneous coronary intervention for acute myocardial infarction: a report from TRANSLATE-ACS. J Am Heart Assoc. 2014 Feb 7;3(1):e000523. doi: 10.1161/JAHA.113.000523.
- Wang TY, McCoy L, Henry TD, Effron MB, Messenger JC, Cohen DJ, Mark DB, Stone GW, Zettler M, Singh M, Fonarow GC, Peterson ED; TRANSLATE-ACS Study Investigators. Early post-discharge bleeding and antiplatelet therapy discontinuation among acute myocardial infarction patients treated with percutaneous coronary intervention. J Am Coll Cardiol. 2014 Apr 29;63(16):1700-2. doi: 10.1016/j.jacc.2013.12.012. Epub 2014 Jan 30. No abstract available.
- Chin CT, Wang TY, Anstrom KJ, Zhu B, Maa JF, Messenger JC, Ryan KA, Davidson-Ray L, Zettler M, Effron MB, Mark DB, Peterson ED. Treatment with adenosine diphosphate receptor inhibitors-longitudinal assessment of treatment patterns and events after acute coronary syndrome (TRANSLATE-ACS) study design: expanding the paradigm of longitudinal observational research. Am Heart J. 2011 Nov;162(5):844-51. doi: 10.1016/j.ahj.2011.08.021.
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart
1 mars 2010
Primärt slutförande (Faktisk)
1 januari 2014
Avslutad studie (Faktisk)
1 januari 2014
Studieregistreringsdatum
Först inskickad
15 mars 2010
Först inskickad som uppfyllde QC-kriterierna
15 mars 2010
Första postat (Uppskatta)
17 mars 2010
Uppdateringar av studier
Senaste uppdatering publicerad (Uppskatta)
29 januari 2016
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
22 december 2015
Senast verifierad
1 december 2015
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- 12549
- H7T-US-B007 (Annan identifierare: Eli Lilly and Company)
Denna information hämtades direkt från webbplatsen clinicaltrials.gov utan några ändringar. Om du har några önskemål om att ändra, ta bort eller uppdatera dina studieuppgifter, vänligen kontakta register@clinicaltrials.gov. Så snart en ändring har implementerats på clinicaltrials.gov, kommer denna att uppdateras automatiskt även på vår webbplats .
Kliniska prövningar på Akut koronarsyndrom
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IRCCS Policlinico S. DonatoRekryteringAnomalous aortic origin of the coronary artery (AAOCA)Italien
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Biotronik AGAvslutadde Novo Lesions in Native coronary arteriesNederländerna, Schweiz, Tyskland, Belgien
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Osaka General Medical CenterAvslutadEmergent coronary procedurJapan
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Claudia SpiesAvslutadOmskärelse, Meatotomy eller Distal Coronary Correction of HypospadiaTyskland
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Tel-Aviv Sourasky Medical CenterAvslutadKonsekutiva ämnen som är lämpliga för en kranskärlssjukdom | Angioplastik av de Novo lesion(er) i Native Coronary | Artärer bör undersökas för behörighet. | Totalt antal 200 patienter som uppfyller urvalet | Kriterier och villig att underteckna det informerade samtycket | vara inskriven i provet.Israel
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RenJi HospitalAvslutadST Segment Elevation Myokardinfarkt | Coronary Slow Flow FenomenKina
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Brian JonasNational Cancer Institute (NCI); Celgene; Pharmacyclics LLC.AvslutadTidigare behandlat myelodysplastiskt syndrom | Myelodysplastiskt syndrom | Terapierelaterat myelodysplastiskt syndrom | Sekundärt myelodysplastiskt syndrom | Refraktärt högrisk myelodysplastiskt syndromFörenta staterna
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI)AvslutadTidigare behandlade myelodysplastiska syndrom | Sekundära myelodysplastiska syndrom | de Novo myelodysplastiska syndromFörenta staterna
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National Cancer Institute (NCI)AvslutadTidigare behandlade myelodysplastiska syndrom | Sekundära myelodysplastiska syndrom | de Novo myelodysplastiska syndromFörenta staterna
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University of Colorado, DenverRekryteringKlinefelters syndrom | Trisomi X | XYY syndrom | XXXY och XXXXY syndrom | Xxyy syndrom | Xyyy syndrom | Xxxx syndrom | Xxxxx syndrom | Xxxyy syndrom | Xxyyy syndrom | Xyyyy syndrom | Man med sexkromosommosaicismFörenta staterna
Kliniska prövningar på ADP-receptorhämmare
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Azienda Ospedaliero Universitaria Maggiore della...Polo AgriFood - Miac Scpa; Albertengo PanettoniAvslutadHyperglykemi | Hyperinsulinism | Appetitivt beteende | Hyperglykemi, postprandial | KonsumentpreferensItalien
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Sheng-Teng HuangAvslutadCoronavirus-sjukdom 2019 | Svårt akut respiratoriskt syndrom Coronavirus 2-infektionTaiwan
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Gretchen Swanson Center for NutritionUniversity of Colorado, Denver; University of California, San Francisco; Children... och andra samarbetspartnersAnmälan via inbjudan
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University of SheffieldGreener Practice, Sheffield; Sheffield Network North Primary Care Network...OkändDepression | Problem med psykisk hälsa
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University of Missouri-ColumbiaNational Library of Medicine (NLM)AvslutadDepression | HIV-infektioner | Hypertoni | Fetma | Diabetes mellitus | Ryggont | Urininkontinens | Irritabel tarmsyndrom | Sömnlöshet | Astma | Ångest | Bihåleinflammation | Axelvärk | Allergisk rinit | Urinvägsinfektion | Vaginit | Bursit | Hyperlipidemi | Esophageal reflux | Benign prostatahypertrofi | Osteoporos (senil) | Symtomatisk klimakterietFörenta staterna
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University of Missouri-ColumbiaNational Library of Medicine (NLM)AvslutadDepression | Kranskärlssjukdom | HIV-infektioner | Rökavvänjning | Hypertoni | Fetma | Diabetes mellitus | Kronisk obstruktiv lungsjukdom | Artros | Hypotyreos | Ryggont | Urininkontinens | Irritabel tarmsyndrom | Diarre | Migränstörningar | Hosta | Sömninitiering och underhållsstörningar | Astma | Obstruktiv sömnapné | Prostatahyperp... och andra villkor
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Jie LiRekrytering
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University of WaterlooUniversity of Guelph; The Weston A. Price FoundationAvslutad
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University of Southern DenmarkThe Danish Medical Research Council; National Board of Health, Denmark; Ministry... och andra samarbetspartnersOkändHjärt-kärlsjukdomar | Diabetes mellitus, typ 2 | Metaboliskt syndrom XDanmark