Application of EULAR Recommendations for Cardiovascular Risk Management in Patients With Rheumatoid Arthritis
Application of EULAR Recommendations for Cardiovascular Risk Management in Patients With Rheumatoid Arthritis in France in the Entire Population of the RSI (Other Branches of the Universal Healthcare Insurance Agency)
Introduction Cardiovascular diseases are the first cause of death in rheumatoid arthritis (RA). In 2010, EULAR Standing Committee for Clinical Affairs provides 10 recommendations for cardiovascular risk management in patients with rheumatoid arthritis, including a cardiovascular risk assessment annually.
The goal of this study is to evaluate the application of EULAR recommendations in real life in patients with RA in the french population. Inclusion criteria: all patients over 18 years old with rheumatoid arthritis treated with at least one DMARDS and/or biologic therapy, affiliated to the RSI (regime social des independents which correspond to other branches of the universal healthcare insurance agency). Non inclusion criteria: patients declared as rheumatoid arthritis without DMARDS or biologic therapy or treated with steroids alone. The following analysis will be performed on the whole database of the RSI, without name identification. Evaluation criteria: at least once a years the prescription of at least one of the following items use in the evaluation of the cardiovascular risk factors: lipides dosage, glycemia, HbA1C, stress test, Carotid ultra-sonography, coronary or lower limbs arteriography, heart ultra-sonography, cardiology clinic, endocrinology clinic. This evaluation will be done on the whole national population of RSI for the year 2011 (01/01/2011 - 31/12/2011). On a subgroup of patients from the region "Provence Alpes Côte d'Azur", the investigators will analyze the year 2009, and compare to year 2011, to evaluate the impact of theses recommendations.
研究概览
地位
研究类型
注册 (预期的)
联系人和位置
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Patients over 18 years, affiliated to RSI, with rheumatoid arthritis treated with at least one DMARDS and/or biologic therapy
Exclusion Criteria:
- patients under 18 years
- Patients declared as rheumatoid arthritis without DMARDS or biologic therapy or treated with steroids alone
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
干预/治疗 |
---|---|
Patient
Patients with rheumatoid arthritis
|
Cardiovascular check-up once a year in patients with rheumatoid arthritis
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
the following items use in the evaluation of the cardiovascular risk factors
大体时间:at time = 2 years
|
At least once a years the prescription of at least one of the following items use in the evaluation of the cardiovascular risk factors:
|
at time = 2 years
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
the following items use in the evaluation of the cardiovascular risk factors on the sub population
大体时间:t=0 and t=2 years
|
The same criteria of primary criteria but on the sub population of Povence Alpes Cote-d'Azur region a comparison of these criteria in 2009 (before EULAR recommendations ) and in 2011 (after EULAR recommendations)
|
t=0 and t=2 years
|
合作者和调查者
调查人员
- 首席研究员:Liana EULLER-ZIEGLER, PU-PH、Centre Hospitalier Universitaire de Nice
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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Cardiovascular check-up的临床试验
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Centers for Disease Control and PreventionNorthwestern University; Emory University; Public Health Solutions完全的
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Shannon E. Sauer-ZavalaNational Institute of Mental Health (NIMH)主动,不招人
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University of MichiganNational Institute on Drug Abuse (NIDA); Brown University; Pennington Biomedical Research Center; Oregon Research Institute 和其他合作者招聘中
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Mary LacyNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)主动,不招人