- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00212953
OPALS Critical Care Sub-Studies
October 13, 2010 updated by: Ottawa Hospital Research Institute
Ontario Prehospital Advanced Life Support (OPALS) Study Phase III Cardiac Arrest and Critical Care Sub-Studies - Chest Pain Sub-Study, Respiratory Sub-Study, and Major Trauma Sub-Study
The purpose of the study is to evaluate the incremental benefit of a full advanced life support EMS program on the outcomes of chest pain, respiratory and major trauma patients.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment
21000
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
Ontario
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Cambridge, Ontario, Canada, N3C 3X4
- Cambridge Base Hospital
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Kingston, Ontario, Canada, K7L 1S4
- Kingston Base Hospital
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London, Ontario, Canada, N6A 4G5
- London Base Hospital
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Mississauga, Ontario, Canada, L6K 3S3
- Halton Base Hospital
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Niagara Falls, Ontario, Canada, L2E 6X2
- Niagara Falls Base Hospital
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Ottawa, Ontario, Canada, K1H 8L6
- Ottawa Base Hospital
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Peterborough, Ontario, Canada, K9J 7C6
- Peterborough Base Hospital
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Sarnia, Ontario, Canada, N7T 6S3
- Lambton Base Hospital
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Sudbury, Ontario, Canada, 705-675-4783
- Sudbury Base Hospital
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Thunder Bay, Ontario, Canada, P7E 1G6
- Thunder Bay Base Hospital
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Windsor, Ontario, Canada, N9A 1E1
- Windsor Base Hospital
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
16 years and older (Child, Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Chest Pain Sub-Study: Adult patients with a complaint of chest pain of an acute nature transported to hospital by ambulance. Patients with a complaint of pain in arms, neck or jaw if consistent with myocardial ischemia. Patients must have an ambulance return code of prompt, urgent, or no patient carried.
- Respiratory Sub-Study: Adult patients with a chief complaint of shortness of breath defined as ACR codes of Respiratory Failure, Shortness of Breath NYD, Pulmonary Edema (CHF), Asthma and had either prehospital assisted ventilation or abnormal respiratory rates (>=24 or <=10)
- Major Trauma Sub-Study: Adult patients who have suffered an injury from any mechanism with an Injury Severity Score of >12 who have been transported to hospital by land ambulance, and who have been entered into the Ontario Trauma Registry (OTR) Comprehensive Data Set.
Exclusion Criteria:
- All Sub-Studies:
- Patients under the age of 16
- Patients who are vital signs absent prior to EMS arrival.
- Chest Pain Sub-Study:
- Patients suffering primarily from respiratory distress, respiratory failure, pulmonary edema, asthma, palpitations or epigastric pain. pain
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Non-Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
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Survival to discharge
|
Secondary Outcome Measures
Outcome Measure |
---|
Disease Specific Quality of Life
|
Generic Quality of Life
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Disease Specific Quality of Life CPC Score and FIM Score
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Performance of ALS Procedures
|
Response Time Intervals
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Length of Stay in Hospital
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Length of Stay in Critical Care Units
|
Ventilator time
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
March 1, 1997
Study Completion (Actual)
May 1, 1999
Study Registration Dates
First Submitted
September 13, 2005
First Submitted That Met QC Criteria
September 13, 2005
First Posted (Estimate)
September 21, 2005
Study Record Updates
Last Update Posted (Estimate)
October 15, 2010
Last Update Submitted That Met QC Criteria
October 13, 2010
Last Verified
October 1, 2010
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 1997576-01H
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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