Adolescent Substance Abuse: Progressive Treatment (ADAPT)

October 8, 2014 updated by: Oregon Research Institute
The purpose of this study is to find out more about how to provide effective further treatment for adolescents who have received six weeks of group therapy for substance-use problems and continue to use drugs. Treatments used in the study include a group therapy (MET/CBT), an individual therapy (CBT), and a family therapy (FFT). The study will look at whether abstinence or a very low level of use is a better guide for deciding whether further treatment is needed, how well different combinations of treatment work to reduce substance use, and whether it is possible to predict in advance which adolescents will respond best to which types of treatment. Study investigators expect that a treatment strategy using what is learned about these issues in the first half of the project to develop an "adaptive" treatment model will work better than a "fixed" treatment to reduce adolescent substance use.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

140

Phase

  • Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • New Mexico
      • Albuquerque, New Mexico, United States, 87102
        • Oregon Res. Inst. Center for Family & Adolescent Research (CFAR)

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

13 years to 18 years (ADULT, CHILD)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  1. 13 to 18 years if age
  2. Meet DSM-IV (APA, 1994) diagnostic criteria for substance abuse or dependence
  3. Live in the Albuquerque metropolitan area or surrounding communities
  4. Sufficient residential stability to permit probable contact at follow-up (e.g., not homeless at time of intake).

Exclusion Criteria:

  1. There is evidence of psychotic or organic state of sufficient severity to interfere with the understanding of study instruments and procedures
  2. The adolescent is deemed dangerous to self or others during evaluation
  3. Services other than outpatient treatment are required for the adolescent (e.g., inpatient, detoxification)
  4. Marijuana use is reported as being less than 13% of days in the previous 90 days.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: TREATMENT
  • Allocation: RANDOMIZED
  • Interventional Model: FACTORIAL
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
ACTIVE_COMPARATOR: 1
Eight weeks of individual CBT for adolescents who have completed six weeks of group therapy and continue to use drugs.
Behavioral: CBT, Cognitive Behavioral Therapy
Eight weekly sessions of individual Cognitive Behavioral Therapy, to develop skills enabling adolescents stop or reduce their drug use.
ACTIVE_COMPARATOR: 2
Eight weeks of FFT for adolescents who have received six weeks of group therapy and continue to use drugs.
Behavioral: FFT, Family Functional Therapy
Eight weekly sessions of Functional Family Therapy designed to strengthen family relationships and build skills to help the adolescent stop or reduce his/her drug use.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Urine drug screens
Time Frame: Pretx, 6, 14 and 22 weeks, 3 and 6 months after initial treatment session
Pretx, 6, 14 and 22 weeks, 3 and 6 months after initial treatment session

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Oregon Research Institute

Investigators

  • Principal Investigator: Holly B Waldron, Ph.D., Oregon Research Institute Center for Family and Adolescent Research (ORI/CFAR)

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2008

Primary Completion (ACTUAL)

August 1, 2013

Study Completion (ACTUAL)

August 1, 2013

Study Registration Dates

First Submitted

May 16, 2008

First Submitted That Met QC Criteria

May 19, 2008

First Posted (ESTIMATE)

May 20, 2008

Study Record Updates

Last Update Posted (ESTIMATE)

October 10, 2014

Last Update Submitted That Met QC Criteria

October 8, 2014

Last Verified

October 1, 2014

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • DA023568
  • R01DA023568 (NIH)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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