French Observatory of Acute Heart Failure (OFICA)

During the last decade, progress has been made in the management of heart failure. However, the changing characteristics of patients and practices in the "real world" and their impact on the prognosis of patients admitted for acute heart failure remain poorly studied.

2000 consecutive patients recruited in a single day in hospitals volunteered to participate in the cohort during a day dedicated.

Study Overview

• Status: Completed
• Conditions: Acute Heart Failure

Detailed Description

The total duration of recruitment is one day (date to be set soon by the Executive Committee): all patients hospitalized, and whatever their date of admission with the diagnosis of heart failure will be selected for the study.

Information on each hospital stay will be obtained at baseline and at the end of the hospitalization by the hospital teams.

A telephone follow-up will be conducted at 3 months among survivors and / or their doctor by CRAs dedicated to the French Society of Cardiology.

• Study Type: Observational
• Enrollment (Actual): 1818

Contacts and Locations

Study Locations

• France
  • Paris, France, 75010
    • Lariboisiere Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Hospitalized patient, whatever the mode of initial admission with acute heart failure (de novo heart failure or decompensation of chronic heart failure)

Description

Inclusion Criteria:

1. Male or female age (e) over 18 years

2. Inpatient, whatever the mode of initial admission with acute heart failure (de novo heart failure or decompensation of chronic heart failure) regardless of severity, corresponding to one of the following clinical situations (clinical criteria in Appendix 1):

   • Pulmonary edema, hypertensive or not
   • congestive heart failure (pulmonary congestion and peripheral edema)
   • cardiogenic shock
   • Insufficient high output cardiac
3. Patients who agreed to participate in the study
4. Isolated right heart failure

Exclusion Criteria:

1. expressed refusal to participate in the study
2. Hospitalization scheduled for review
3. Background surgery (immediate postoperative period)
4. Diagnosis of acute heart failure reversed in favor of an alternative diagnosis before discharge from hospital

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Patient with acute heart failure; Hospitalized patient, whatever the mode of initial admission with acute heart failure

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Survival at 3 months	Analyze survival 3 months after the end of initial hospitalization	3 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Hospital Methods	Compare methods of care based on clinical characteristics and hospital structures.	3 months
Patterns of admission	Analyze patterns of admission and discharge of patients, depending on their characteristics	3 months
Co-morbidities	Analyze the co-morbidities and their impact on care and survival	3 months
Drug treatments	Analyze the evolution of drug treatment between the output and monitoring to 3 months	3 months
Resources specific diagnostic	Analyze the use of resources specific diagnostic: measurement of BNP or NTproBNP, conducting echocardiogram, coronary angiography, Holter-ECG, Cardiac MRI, Cardiac CT	3 months
Therapeutic resources	Analyze the use of therapeutic resources based on specific clinical features: intensive care, ventilation, inotropes, ultrafiltration, introduction of beta-blockers, stimulation, implantable cardioverter defibrillator, circulatory support, graft	3 months
During of stay	Analyze the duration of stay according to clinical characteristics.	3 months

Collaborators and Investigators

• Sponsor: French Cardiology Society
• Investigators: Principal Investigator: Damien DL LOGEART, French Cardiology Society

Publications and helpful links

General Publications

• Logeart D, Isnard R, Resche-Rigon M, Seronde MF, de Groote P, Jondeau G, Galinier M, Mulak G, Donal E, Delahaye F, Juilliere Y, Damy T, Jourdain P, Bauer F, Eicher JC, Neuder Y, Trochu JN; Heart Failure of the French Society of Cardiology. Current aspects of the spectrum of acute heart failure syndromes in a real-life setting: the OFICA study. Eur J Heart Fail. 2013 Apr;15(4):465-76. doi: 10.1093/eurjhf/hfs189. Epub 2012 Nov 27.
• Logeart D. [The OFICA study of acute heart failure]. Soins. 2013 Apr;(774):35. No abstract available. French.

Study record dates

Study Major Dates

• Study Start: March 1, 2009
• Primary Completion (Actual): December 1, 2010
• Study Completion (Actual): February 1, 2011

Study Registration Dates

• First Submitted: March 1, 2010
• First Submitted That Met QC Criteria: March 4, 2010
• First Posted (Estimated): March 5, 2010

Study Record Updates

• Last Update Posted (Actual): September 13, 2023
• Last Update Submitted That Met QC Criteria: September 11, 2023
• Last Verified: September 1, 2023

More Information

Terms related to this study

• Keywords: acute heart failure
• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Failure
• Other Study ID Numbers: SFC-OFICA