Nutritional Quality of Egg Proteins and Effect on Satiety

October 1, 2025 updated by: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
The project aims to precisely quantify the postprandial amino acid utilization of egg proteins in vivo in humans, and also to assess their satiating power, in relation with nutrient postprandial waves and incretin secretions. For that purpose, 2 independent studies are conducted. The first one is realized using stable isotopes on 8 volunteers ingesting an egg test meal. The second one is a cross over design performed on 30 volunteers to compare the satiating effect of 2 equivalent snacks: whole eggs or cottage cheese.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

43

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Bobigny, France, 93
        • Centre de Recherche sur Volontaires
      • Nantes, France, 44
        • Centre de Recherche sur Volontaires

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 40 years (Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Healthy volunteers
  • BMI between 18 and 25

Exclusion Criteria:

  • Allergy to egg or milk protein
  • Digestive or metabolic pathology
  • Positiveness to HIV, Hepatitis B and C
  • Smokers

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Egg
Dietary supplement: Egg snack
subject consume 4 cooked whole eggs, providing 380 kcal
Experimental: Cottage cheese
Dietary supplement: Cottage cheese
Subjects consume 200 g of cottage cheese, providing 380 kcal

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
energy intake at lunch following the snack
Dietary amino acid utilization
transfer of stables isotopes used as intrinsic markers of egg proteins to metabolic pools

Secondary Outcome Measures

Outcome Measure
Measure Description
plasma incretin concentrations
insulin, glucagon, GLP-1, PYY, ghrelin, GIP
postprandial nutrient waves
plasma glucose, cholesterol, triglyceride, urea
neoglucogenesis
Endogenous production of glucose and contribution of dietary amino acids

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Collaborators

National Research Agency, France

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

February 1, 2009

Study Registration Dates

First Submitted

June 30, 2010

First Submitted That Met QC Criteria

June 30, 2010

First Posted (Estimated)

July 1, 2010

Study Record Updates

Last Update Posted (Estimated)

October 6, 2025

Last Update Submitted That Met QC Criteria

October 1, 2025

Last Verified

June 1, 2010

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • OVONUTRIAL

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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