Breast Cancer Prevention Education

Disseminating Breast Cancer Prevention to African American Women

We will develop and evaluate a community-based approach for disseminating comparative effective reviews (CERs) about breast cancer prevention to African American women. The specific aims of our research, as shown below, will target this population because of persistent disparities in breast cancer morbidity and mortality among this population. Our primary aims are:

1. To evaluate uptake of a community-based strategy for disseminating CERs about breast cancer prevention to African American women based on sociodemographic characteristics, beliefs about medical research, and medical history. We predict that participation in a community forum will be higher among women with greater socioeconomic resources, those who have a family history of breast cancer, and women who have more positive beliefs about research.
2. To evaluate the impact of evidential versus non-evidential content about breast cancer prevention on psychological and behavioral outcomes that include: knowledge of breast cancer risk factors and prevention strategies, communication with individuals in their social and medical network, and distrust of medical research. We predict that women who receive evidential content that is specific for African American women will report greater knowledge about breast cancer risk factors and prevention strategies, will be more likely to discuss breast cancer prevention strategies with individuals in their social and medical network, and will report greater reductions in distrust of medical research compared to those who receive non-evidential content.

Study Overview

• Status: Completed
• Conditions: Breast Cancer Prevention
• Intervention / Treatment: Behavioral: Comparison of evidential versus non-evidential education on women's breast cancer prevention behaviors

• Study Type: Interventional
• Enrollment (Actual): 366
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Pennsylvania
    • Philadelphia, Pennsylvania, United States, 19104
      • University of Pennsylvania Center for Community Based Research and Health Disparities

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 35 years to 70 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Female

Description

Inclusion Criteria:

• African American women
• Ages 35-70
• No personal history of cancer
• Resident of Philadelphia metropolitan area

Exclusion Criteria:

• Non-African American
• Male
• Under 35 or over 70 years of age
• Personal history of cancer
• Not a resident of Philadelphia Metropolitan Area

Study Plan

How is the study designed?

Design Details

• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Triple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Evidential Group; Participants in this group will receive education about breast cancer prevention and specific information about African American women and breast cancer risk.	Behavioral: Comparison of evidential versus non-evidential education on women's breast cancer prevention behaviors; Participants will be randomized to either the evidential or non-evidential group. Both groups will receive primarily the same information, except one group will receive information that is more tailored to African American women, while participants in the other group will receive general information about breast cancer prevention.
Active Comparator: Non-Evidential Group; Participants in this group will receive general information about breast cancer prevention without anything specific to African American women.	Behavioral: Comparison of evidential versus non-evidential education on women's breast cancer prevention behaviors; Participants will be randomized to either the evidential or non-evidential group. Both groups will receive primarily the same information, except one group will receive information that is more tailored to African American women, while participants in the other group will receive general information about breast cancer prevention.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Intervention uptake	Assessment of participants' attendance at a session.	1 session
knowledge about breast cancer prevention	Measurement of women's knowledge about breast cancer prevention at three and six months post intervention compared to baseline measurements.	6 months
Communication about breast cancer prevention	Assessment of the extent to which women discuss breast cancer prevention with their health care providers at three and six months post intervention compared to at baseline.	6 months
Distrust of medical research	Assessment of the extent to which participants harbor distrust for the medical establishment three and six months post intervention compared to at baseline.	6 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Education	Assessment of the relationship between participants' education and primary outcomes.	baseline
Family history	Assessment of the relationship between participants' family history and the primary outcomes.	baseline
Beliefs about research	Assessment of the relationship between participants' beliefs about research and the primary outcomes.	baseline

Collaborators and Investigators

• Sponsor: University of Pennsylvania

Study record dates

Study Major Dates

• Study Start: August 1, 2010
• Primary Completion (Actual): May 1, 2014
• Study Completion (Actual): May 1, 2014

Study Registration Dates

• First Submitted: February 17, 2011
• First Submitted That Met QC Criteria: February 17, 2011
• First Posted (Estimate): February 18, 2011

Study Record Updates

• Last Update Posted (Estimate): August 19, 2016
• Last Update Submitted That Met QC Criteria: August 17, 2016
• Last Verified: August 1, 2016

More Information

Terms related to this study

• Keywords: breast cancer; breast cancer prevention; African American women
• Additional Relevant MeSH Terms: Skin Diseases; Neoplasms; Neoplasms by Site; Breast Diseases; Breast Neoplasms
• Other Study ID Numbers: 1R18HSO19339-01