- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01601964
Vascular Endothelial Growth Factor Levels in Ectopic Pregnancy (VEGF)
The aim of this study is to determine plasma Vascular Endothelial Growth Factor level and change in patient with ectopic pregnancy who needs to surgical treatment.
Patient with ectopic pregnancy diagnosed and treated with medically or surgically will be included in the study. This is an observational study.The plasma Vascular Endothelial Growth Factor level will be measured first day and two day after the diagnosis of ectopic pregnancy.
Study Overview
Status
Conditions
Detailed Description
This study is a prospective, observational, single-center study. Ethical approval was obtained from the Institutional Review Board. This study will be completed with 30 patients with ectopic pregnancy. An intervenous cannula will be centrifuged for 15 minutes at 1000 g within 30 minutes of collection. Aliquots of plasma will be added to eppendorf tubes and stored at -20°C.
Plasma Vascular Endothelial Growth Factor levels will be measured using a Human VEGF-A Platinum ELISA kit (bioscience company, Catalog No: 00122, Santa Clara, California, USA). All assays will be performed according to the manufacturer's instructions. The test kit sensitivity is 2.5 pg/ml. Intracycle variability is %4-6, intercycle variability is %8-10.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
-
Istanbul, Turkey
- Bagcilar Training and Research Hospital
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients who suspected ectopic pregnancy
Exclusion Criteria:
- hemodynamically unstable patient
- healthy pregnancy (a healthy increase in ß HCG)
- missed abortion
- incomplete abortion
- The patient who need immediate surgical treatment
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
---|
Follow-up or medical treatment.
medical treatment
|
Surgical treatment
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
The primary Outcome Measure of this study is to determine plasma Vascular Endothelial Growth Factor cut-off level in patient with ectopic pregnancy who needs to surgical treatment.
Time Frame: 3-4 months
|
3-4 months
|
Collaborators and Investigators
Investigators
- Principal Investigator: TANER A USTA, M.D., Bagcilar Training and Research Hospital, Istanbul, Turkey.
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- BEH GynObs-1
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Complication Following Ectopic Pregnancy
-
Xijing HospitalUnknownIntubation Complication | Complication of Ventilation Therapy | Postoperative; Dysfunction Following Cardiac Surgery
-
Gazi UniversitySmart Alfa Teknoloji San. ve Tic. A.S.CompletedComplication Following Peripheral Nerve Block (Diagnosis)Turkey
-
Centre Hospitalier Universitaire de BesanconTerminatedPostoperative; Dysfunction Following Cardiac Surgery | Transfusion Related ComplicationFrance
-
Instituto Valenciano de Infertilidad, IVI VALENCIACompleted
-
Sohag UniversityRecruitingWoman With Tubal Ectopic PregnancyEgypt
-
University of PretoriaCompletedRuptured Ectopic PregnancySouth Africa
-
Federal University of São PauloCompleted
-
Shanghai First Maternity and Infant HospitalShanghai Pudong Hospital; Shanghai Seventh People's Hospital; Shanghai Zhoupu...Not yet recruitingTubal Pregnancy | Tubal-preserving Treatment of Tubal Ectopic Pregnancy | Pregnancy PreparationChina
-
University of PalermoDamascus University; University of DebrecenCompleted
-
Tel-Aviv Sourasky Medical CenterUnknownEctopic Pregnancies