Effect of Serving Size and Addition of Sugar on the Glycemic Response Elicited by Oatmeal (Panther)

July 22, 2015 updated by: Glycemic Index Laboratories, Inc

Effect of Varying Amounts of β-glucan and Sucrose in Oatmeal on Glycemic Response

The purpose of this study was to determine the impact of serving size and the addition of sugar on the glycemic response elicited by oatmeal compared to that elicited by cream of rice cereal.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

38

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Canada
    • Ontario
      • Toronto, Ontario, Canada, M5C 2N8
        • Glycemic Index Laboratories, Inc.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 75 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • body mass index (BMI) 20.0 - 34.9 kg/m²

Exclusion Criteria:

  • known to have diabetes
  • use of medications considered by the principal investigator to influence glycemic responses

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: 30g oats
Classic Quick Quaker Oats
Other: Classic Quaker Quick Oats
Various doses of oats without or with sugar
Other: 30g oats plus 9g sugar
Classic Quick Quaker Oats
Other: Classic Quaker Quick Oats
Various doses of oats without or with sugar
Other: 40g oats
Classic Quick Quaker Oats
Other: Classic Quaker Quick Oats
Various doses of oats without or with sugar
Other: 60g oats
Classic Quick Quaker Oats
Other: Classic Quaker Quick Oats
Various doses of oats without or with sugar
Other: 22g cream of rice cereal
Cream of Rice Cereal, B&G Foods, Inc.
Other: Cream of Rice Cereal
Various doses of cereal without sugar
Other: 29g cream of rice cereal
Cream of Rice Cereal, B&G Foods, Inc.
Other: Cream of Rice Cereal
Various doses of cereal without sugar
Other: 33g cream of rice cereal
Cream of Rice Cereal, B&G Foods, Inc.
Other: Cream of Rice Cereal
Various doses of cereal without sugar
Other: 44g cream of rice cereal
Cream of Rice Cereal, B&G Foods, Inc.
Other: Cream of Rice Cereal
Various doses of cereal without sugar

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Incremental area under the blood glucose response curve
Time Frame: For 2 hours after consuming each test meal
For 2 hours after consuming each test meal

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Peak rise of blood glucose
Time Frame: During 2 hour period after consuming each test meal
The highest concentration of blood glucose achieved after eating minus the fasting blood glucose.
During 2 hour period after consuming each test meal
Time to peak
Time Frame: During 2 hour period after consuming each test meal
The time at which the peak rise of blood glucose occured.
During 2 hour period after consuming each test meal
Mean rate of decline in blood glucose
Time Frame: During 2 hour period after consuming each test meal
The rate of change in blood glucose between consecutive time points (Tx and T(x+1)) was calculated as: Rx = (Gx G(x+1))/(Tx-T(x+1)), where G(x+1) and Gx were the glucose concentrations at times T(x+1) and Tx, respectively. The mean rate of decline in blood glucose (Mean RD) was calculated as the weighted average of all the Rx values from the time of the peak glucose concentration to 120 min, with the weight based on the length of the time interval.
During 2 hour period after consuming each test meal
Maximum rate of decline in blood glucose
Time Frame: During 2 hour period after consuming each test meal
The rate of change in blood glucose between consecutive time points (Tx and T(x+1)) was calculated as: Rx = (Gx G(x+1))/(Tx-T(x+1)), where G(x+1) and Gx were the glucose concentrations at times T(x+1) and Tx, respectively. . The maximum rate in blood glucose decline (Max RD) was calculated as the maximum of all the Rx values from the time of the peak glucose concentration to 120 min.
During 2 hour period after consuming each test meal
Time to baseline
Time Frame: During 2 hour period after consuming each test meal
The time for blood glucose to return to baseline was linearly interpolated between the first blood glucose concentration below fasting and the previous value; if blood glucose did not reach baseline, Bt was taken to be 120min.
During 2 hour period after consuming each test meal

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Glycemic Index Laboratories, Inc

Collaborators

PepsiCo Global R&D
Applied Statistics and Consulting

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

November 1, 2013

Primary Completion (Actual)

February 1, 2014

Study Completion (Actual)

February 1, 2014

Study Registration Dates

First Submitted

July 21, 2015

First Submitted That Met QC Criteria

July 22, 2015

First Posted (Estimate)

July 23, 2015

Study Record Updates

Last Update Posted (Estimate)

July 23, 2015

Last Update Submitted That Met QC Criteria

July 22, 2015

Last Verified

July 1, 2015

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • GIL-1404

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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