A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention

February 14, 2023 updated by: The First Hospital of Qinhuangdao
Several approaches have been proposed to reduce the risk of RAO, including anticoagulation, immediate postprocedural sheath removal, and a small sheath/radial artery ratio. Doppler ultrasound examination showed that interrupted blood flow in RA tend to occur in the proximal end rather than distal part of the artery,which was ignored by a majority of interventional cardiologists. Different insights into occlusion location may lead to different options of sheath materials, models, catheters and puncture access. Thus, the investigators designed this present study to explore the reason of radial artery endothelial dysfuction and damage and occlusion location by flow-mediated dilation (FMD) to determine the suitable method to reduce occlusion risk during TRI.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

600

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Hebei
      • Qinhuangdao, Hebei, China, 066000
        • Qingsheng wang

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • admitted for transradial catheterization.

Exclusion Criteria:

  • femoral access, arterial circulatory disease, pathological Allen tests, decompensated heart failure, chronic renal failure

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: radial artery occlusion
Radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination.
Procedure: Percutaneous coronary intervention
Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease
Other: radial artery normal
Radial artery normal was blood flow signal by Doppler ultrasound
Procedure: Percutaneous coronary intervention
Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
radial artery occlusion
Time Frame: 6 month
radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination
6 month

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

The First Hospital of Qinhuangdao

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

July 10, 2016

Primary Completion (Actual)

September 5, 2016

Study Completion (Actual)

October 1, 2017

Study Registration Dates

First Submitted

July 4, 2016

First Submitted That Met QC Criteria

July 12, 2016

First Posted (Estimate)

July 13, 2016

Study Record Updates

Last Update Posted (Actual)

February 15, 2023

Last Update Submitted That Met QC Criteria

February 14, 2023

Last Verified

February 1, 2023

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 21735

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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