- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03347903
Prevalence and Clinical Characteristics of Patients With Jackhammer Esophagus and Symptoms of Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) is involved in the development of esophageal motility disorders like Jackhammer esophagus (JE), a novel hypercontractile condition that was associated with progression to achalasia and limited outcomes following surgical anti-reflux therapy.
This trial was designed to assess the prevalence and characteristics of JE in patients with typical symptoms of GERD and responsiveness to PPI therapy.
Study Overview
Status
Conditions
Detailed Description
Study Type
Enrollment (Actual)
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patients with symptoms of gastroesophageal reflux disease and diagnosis of Jackhammer esophagus
Exclusion Criteria:
- patients not willing to participate data or undergo screening for gastroesophageal reflux disease
Study Plan
How is the study designed?
Design Details
- Observational Models: Cohort
- Time Perspectives: Prospective
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Prevalence of Jackhammer esophagus in patients referred with symptoms of gastroesophageal reflux disease
Time Frame: January 2014- May 2017
|
All patients that are referred to our center with symptoms of gastroesophageal reflux disease routinely undergo high-resolution manometry.
We assess how many patients are diagnosed with Jackhammer esophagus
|
January 2014- May 2017
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Symptom perception
Time Frame: January 2014- May 2017
|
We assess which symptoms are perceived by the patients diagnosed with Jackhammer esophagus.
All data are observed during an interview at the high-resolution manometry
|
January 2014- May 2017
|
Prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus
Time Frame: Januar 2014- May 2017
|
All patients that are referred to our center are evaluated for gastroesophageal reflux disease.
We assess the prevalence of gastroesophageal reflux disease in patients with Jackhammer esophagus diagnosed by ambulatory pH monitoring.
|
Januar 2014- May 2017
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Sebastian Schoppmann, MD, Vice Chair of Department of General Surgery
Publications and helpful links
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 1164/2017
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Esophageal Motility Disorders
-
The Catholic University of KoreaUnknownEsophageal Motility DisorderKorea, Republic of
-
Chinese University of Hong KongUnknownPrimary Esophageal Motility Disorders Including Achalasia and Hypertensive LESChina
-
Cantonal Hospital of St. GallenUniversity of ZurichUnknownIneffective Motility | Diffuse Esophageal Spasms | Achalasia-Like DysmotilitySwitzerland
-
Assistance Publique Hopitaux De MarseilleUnknownOesophageal Motility DisorderFrance
-
Carlos Robles-MedrandaCompletedGastroesophageal Reflux Disease and Esophageal Motility DisordersEcuador
-
Mayo ClinicTerminatedAchalasia | Esophageal Achalasia | Achalasia, EsophagealUnited States
-
First Affiliated Hospital, Sun Yat-Sen UniversityCompleted
-
Shanghai Zhongshan HospitalUnknownEsophageal AchalasiaChina
-
Seoul National University HospitalIlDong Pharmaceutical Co LtdCompletedEsophageal DiseaseKorea, Republic of
-
L. Michael BruntUniversity of Oregon; Northwestern University; Duke University; University of WashingtonCompletedEsophageal AchalasiaUnited States