Nasopharyngeal Airway Guide Nasogastric Tube Placement

A Nasopharyngeal Airway Facilitates Nasogastric Intubation in Anesthetized Intubated Patients: A Randomized Controlled Trial

Nasogastric tube placement is essential for various surgery and critically ill patients. However, NG tube insertion in anesthetized, paralyzed, and intubated or unconscious patients may be difficult, with reported success rate less 50% on the first attempt without any auxiliary devices. Endotracheal tube intubation narrow the space of oropharynx and hypopharynx. Loss ability to swallow and tongue drop also made the NG tube coil in the mouth easily. Investigators assume nasopharyngeal airway can facilitate NG tube insertion by opening a channel from nostril to epiglottis and reduce complications by protecting nasal cavity while inserting NG.

Study Overview

• Status: Completed
• Conditions: Anesthesia, General; Nasogastric Tube; Nasopharyngeal Airway
• Intervention / Treatment: Procedure: With nasopharyngeal airway; Procedure: Without nasopharyngeal airway

• Study Type: Interventional
• Enrollment (Actual): 108
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Taiwan
  • Taipei, Taiwan, 10507
    • Chang Gung Memorial Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Patient should be > 20 years old, ASA 1~3 under going schedule general anesthesia with endotracheal tube intubation
• Patient who required NG tube placement for perioperative care

Exclusion Criteria:

• Coagulation abnormality (PLT≤100000, INR>1.2 & PT≥13)
• Hemodynamic unstable (with inotropic agent use)
• Arrythmia
• Esophageal varices or stricture, Esophageal cancer, trauma or previous esophageal surgery
• Gastric cancer involve cardiac orifice
• Corrosive chemical (strong acid or alkali) ingestion
• Skull base fracture
• Recent nasal surgery, nasal fracture or severe nasal obstruction
• Loose teeth that make endotracheal tube can not fix right side

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: NG tube placement with nasopharyngeal tube	Procedure: With nasopharyngeal airway; Nasopharyngeal airway is previously inserted into selected nostril. NG tube is properly lubricated and placed through Nasopharyngeal airway.
Active Comparator: NG tube placement without nasopharyngeal tube	Procedure: Without nasopharyngeal airway; NG tube is properly lubricated and placed into selected nostril

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
First attempt successful rate	with or without Nasopharyngeal airway assistance	can be know after NG tube placement immediately
Second attempt successful rate	with or without Nasopharyngeal airway assistance	can be know after NG tube placement immediately
Overall successful rate insertion	with or without Nasopharyngeal airway assistance	can be know after NG tube placement immediately
Time cost during NG tube placement	with or without Nasopharyngeal airway assistance	can be know after NG tube placement immediately

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Incidence of NG tube coiling	with or without Nasopharyngeal airway assistance during NG tube insertion	can be know after NG tube placement immediately
Incidence of NG tube kinking	with or without Nasopharyngeal airway assistance during NG tube insertion	can be know after NG tube placement immediately
Incidence of NG tube knotting	with or without Nasopharyngeal airway assistance during NG tube insertion	can be know after NG tube placement immediately
Incidence of epistaxis after NG tube placement	with or without Nasopharyngeal airway assistance during NG tube insertion	can be know after NG tube placement immediately
Mean blood pressure change after NG tube placement	with or without Nasopharyngeal airway assistance	can be know after NG tube placement immediately
Heart rate change after NG tube placement	with or without Nasopharyngeal airway assistance	can be know after NG tube placement immediately

Collaborators and Investigators

• Sponsor: Chang Gung Memorial Hospital

Publications and helpful links

General Publications

• Huang TY, Lin JR, Chung YT. A preinstalled nasopharyngeal airway in the right nasal passageway to facilitate nasogastric intubation in anesthetized and intubated patients: a prospective randomized controlled trial. BMC Gastroenterol. 2020 Nov 3;20(1):365. doi: 10.1186/s12876-020-01514-6.

Study record dates

Study Major Dates

• Study Start (Actual): October 24, 2018
• Primary Completion (Actual): September 3, 2019
• Study Completion (Actual): September 3, 2019

Study Registration Dates

• First Submitted: October 4, 2018
• First Submitted That Met QC Criteria: October 4, 2018
• First Posted (Actual): October 5, 2018

Study Record Updates

• Last Update Posted (Actual): February 26, 2020
• Last Update Submitted That Met QC Criteria: February 23, 2020
• Last Verified: April 1, 2019

More Information

Terms related to this study

• Other Study ID Numbers: 201800138A3

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: Yes