Analgesia in ÖAMTC Helicopter Emergency Service in Austria

Analgesia in ÖAMTC Helicopter Emergency Service in Austria: A Retrospective Analysis

A sufficient analgesia in injured or sick people is the main goal of physicians treating a patient. In emergency medicine potent analgesia like ketamine or opioids are routinely used. It is unknown if there are any severe side effects or if the use is safe while in use in a Helicopter Emergency Service equipped with emergency physicians.

Study Overview

• Status: Completed
• Conditions: Emergencies; Pain, Acute; Trauma, Multiple; Safety; Analgesics; Accident; Field Physician Care; Hypnotics
• Intervention / Treatment: Other: analgesics; Other: hypnotics

• Study Type: Observational
• Enrollment (Actual): 35000

Contacts and Locations

Study Locations

• Austria
  • Innsbruck, Austria, 6020
    • General and Surgical Critical Care Medicine, Medical University of Innsbruck

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

All patients screened with the described inclusion criteria - eligible to be included in analysis.

Description

Inclusion Criteria:

• Analgesia or use of hypnotics in ÖAMTC Air Ambulance Service in Austria 2000-2016

Exclusion Criteria:

• No analgesia, or analgesia use not in connection to ÖAMTC Air Ambulance Service. Analgesia given not in the period of examination (2000-2016)

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Patient given analgesics or hypnotics; All patients treated with any kind of analgesics or hypnotics are analyzed and compared.	Other: analgesics; analgesics given to a patient treated from HEMS; Other: hypnotics; hypnotics given to a patient treated from HEMS

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Successful analgesia	Change in reported pain severity before and after treatment with analgesic. (Numeric Rating Scale, NRS, eleven-point scale reporting no pain=0, to maximum pain=10; 1-3 mild pain, 4-6 moderate pain, 7-10 severe pain)	2000-2016
Analgesic, drug type	Use of analgesic (n= type of analgesic)	2000-2016
Analgesic, frequency	Use of analgesic (n= frequency how often analgesic is used)	2000-2016
Analgesic, amount of analgesics	Use of analgesic (n= amount of analgesic used in mg or µg)	2000-2016

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Side effects	Type of side effect (respiratory arrest after use, hypoxemia, desaturation (SpO2<90%), dead)	2000-2016
Frequency of side effects	Frequency of side effects (frequency of side effect/n=total number of analgesic use; very common>=1/10, common>=1/100 and<1/10, uncommon >=1/1000 and <1/100, rare >=1/10000 and <1/1000, very rare <1/10000)	2000-2016
Severity of side effect	severity of side effect (0=none, 1=mild, 2=moderate, 3=severe, 4=potentially life threatening)	2000-2016

Collaborators and Investigators

• Sponsor: Medical University Innsbruck
• Investigators: Principal Investigator: Mathias Ströhle, Dr, General and Surgical Critical Care Medicine, Medical University of Innsbruck

Study record dates

Study Major Dates

• Study Start (Actual): December 1, 2018
• Primary Completion (Actual): October 26, 2019
• Study Completion (Actual): February 26, 2021

Study Registration Dates

• First Submitted: November 26, 2018
• First Submitted That Met QC Criteria: November 29, 2018
• First Posted (Actual): November 30, 2018

Study Record Updates

• Last Update Posted (Actual): September 8, 2021
• Last Update Submitted That Met QC Criteria: September 7, 2021
• Last Verified: September 1, 2021

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Pain; Neurologic Manifestations; Wounds and Injuries; Disease Attributes; Emergencies; Acute Pain; Multiple Trauma; Physiological Effects of Drugs; Central Nervous System Depressants; Peripheral Nervous System Agents; Sensory System Agents; Analgesics; Hypnotics and Sedatives
• Other Study ID Numbers: AN2015-0068 347/4.13 381/5.19

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No