Comparing the Position of Collagen Membrane During Immediate Implant Placement

February 16, 2026 updated by: Zainab hafez, Ain Shams University

Compraing the Effect of Placement of Collagen Membrane Inside the Extraction Socket and Outside it During Immediate Implant Placement

evaluation of the use of collagen membrane inside the socket and outside it during immediate implant placement

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Twenty patients, who are candidates for immediate implant placement, will participate in this prospective clinical trial.

Group 1(10 patients) :

immediate implant placement with bone graft and collagen memebrane outside the buccal plate

Group 2 (Control group)(10 patients) :

immediate implant placement with bone graft and collagen memebrane inside the buccal plate assessment of the buccal bone thickness assessment of soft tissue thickness

• Esthetic outcome evaluation Will be done using the root coverage esthetic score (Cairo et al. 2009) that include

Both evaluations will be done at 3, 6 and 9 months

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Cairo Governorate
      • Cairo, Cairo Governorate, Egypt
        • Faculty Of Dentistry Ain Shams University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 40 years (Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Systemically free patients (American Society of Anesthesiologists I; ASA I).
  • Age range (20 -50) years.
  • Good compliance with the plaque control instructions following initial therapy.
  • Patients diagnosed badly decayed tooth in esthetic zone indicated for immediate implant placement
  • Availability for follow up and maintenance program.

Exclusion Criteria:

  • Patient suffering from periodontitis
  • Presence of smoking habit.
  • Presence of occlusion interference.
  • Pregnant and lactating females.
  • Vulnerable group of patients (handicapped, mentally retarded and prisoners).

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: collagen membrane inside
during immediate implant placement collagen membrane will be placed into the jumping gap
Procedure: Collagen membrane inside
during immediate implant placement the collagen membrane will be placed in the jumping gap
Active Comparator: collagen membrane outside
during immedoate implant placement collagen membrane will be placed on the outersurface of the buccal plate of bone
Procedure: Collagen membrane outside
during immediate implant placement the collagen membarne will be placed on the surface of the buccal plate of bone

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
buccal plate of bone thickness
Time Frame: baseline 12 months
assessment of the buccal plate of bone will be determined in mm from CBCT
baseline 12 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
soft tissue thickness (Volumetric assessment)
Time Frame: baseline, 6 and 12 months
Preoperative scanning will be done. At 6,12 months after surgical procedure the same procedure will be done to determine the soft tissue thickness after the surgery. The difference between the tissue thickness before and after
baseline, 6 and 12 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ain Shams University

Investigators

  • Study Chair: Mai Shafik, professor, Misr international univeristy

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2018

Primary Completion (Actual)

January 1, 2020

Study Completion (Actual)

January 1, 2020

Study Registration Dates

First Submitted

January 1, 2020

First Submitted That Met QC Criteria

January 9, 2020

First Posted (Actual)

January 13, 2020

Study Record Updates

Last Update Posted (Actual)

February 18, 2026

Last Update Submitted That Met QC Criteria

February 16, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 453

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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