Associations Between Vision and Brain Function

August 14, 2022 updated by: Haotian Lin, Sun Yat-sen University

Quantitative Assessment of the Vison Using Structural and Functional Indicators and Associations With Brain Function

Case-control studies and meta-analysis have reported that several ocular features, especially the thickness of the peripapillary retinal nerve fiber layer and visual acuity, are related to the brain degeneration and cognitive impairment. In our study, we aim to quantitatively assess ocular features using structural and functional indicators and define its associations with brain development and intelligence in children.

Study Overview

Status

Recruiting

Conditions

Study Type

Observational

Enrollment (Anticipated)

200

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • China
    • Guangdong
      • Guangzhou, Guangdong, China, 510060
        • Recruiting
        • Zhongshan Ophthalmic Center, Sun Yat-sen Univerisity
        • Contact:
        • Principal Investigator:
          • Haotian Lin, Ph.D

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

3 years to 12 years (Child)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Healthy children aged 3 to 12 years old. Patients who have been diagnosed with nervous system diseases were excluded.

Description

Inclusion Criteria:

  • age from 3 to 12 years old

Exclusion Criteria:

  • diagnosed with nervous system disease before

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Other
  • Time Perspectives: Cross-Sectional

Cohorts and Interventions

Group / Cohort
Healthy group
Mild visual impairment group
Moderate and severe visual impairment group

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
the visual information processing function
Time Frame: recorded at enrollment
collected with the electroencephalogram
recorded at enrollment
best corrected visual acuity
Time Frame: recorded at enrollment
collected with visual acuity chart
recorded at enrollment

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
refractive status
Time Frame: recorded at enrollment
the refractive status of both eyes
recorded at enrollment
intraocular pressure
Time Frame: recorded at enrollment
the intraocular pressure of both eyes
recorded at enrollment
fundus picture
Time Frame: recorded at enrollment
the fundus pictures of both eyes
recorded at enrollment

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sun Yat-sen University

Investigators

  • Principal Investigator: Haotian Lin, M.D,Ph.D, Zhongshan Ophthalmic Center, Sun Yat-sen University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 25, 2022

Primary Completion (Anticipated)

December 30, 2022

Study Completion (Anticipated)

April 30, 2023

Study Registration Dates

First Submitted

December 30, 2019

First Submitted That Met QC Criteria

January 10, 2020

First Posted (Actual)

January 13, 2020

Study Record Updates

Last Update Posted (Actual)

August 16, 2022

Last Update Submitted That Met QC Criteria

August 14, 2022

Last Verified

August 1, 2022

More Information

Terms related to this study

Other Study ID Numbers

  • VISION202201

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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