Automated Quantification of Radiologic Pulmonary Alteration During Acute Respiratory Failure (QUANTICO-RETRO)

April 14, 2023 updated by: University Hospital, Strasbourg, France

Automated Quantification of Radiologic Pulmonary Alteration During Acute Respiratory Failure: Application to the COVID-19 Pandemic

Automated quantification of the pulmonary volume impaired during acute respiratory failure could be helpful to assess patient severity during COVID-19 infection or perioperative medicine, for example.

This study aim at assessing the correlation between the amount of radiologic pulmonary alteration and the clinical severity in two clinical situation :

  1. SARS-CoV-2 infections
  2. Postoperative hypoxemic acute respiratory failure

Study Overview

Status

Recruiting

Intervention / Treatment

Study Type

Observational

Enrollment (Anticipated)

1000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

      • Strasbourg, France, 67098
        • Recruiting
        • HÔPITAUX UNIVERSITAIRES DE STRASBOURG, Hôpital de Hautepierre, Service de Réanimation Médicale
        • Sub-Investigator:
          • Francis VEILLON, MD
        • Principal Investigator:
          • Eric NOLL, MD
        • Contact:
        • Contact:
        • Sub-Investigator:
          • Pierre DIEMUNSCH, MD
        • Sub-Investigator:
          • Julien POTTECHER, MD
        • Sub-Investigator:
          • Mickaël OHANA, MD
        • Sub-Investigator:
          • Francis SCHNEIDER, MD
        • Sub-Investigator:
          • Bernard GOICHOIT, MD
      • Vandœuvre-lès-Nancy, France, 54500
        • Not yet recruiting
        • Hôpitaux Universitaires de Nancy Service d'anesthésie réanimation Hôpital de Brabois
        • Contact:
        • Sub-Investigator:
          • Valérie CROISE-LAURENT, MD
        • Principal Investigator:
          • Claude MEISTELMAN, MD

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

N/A

Sampling Method

Non-Probability Sample

Study Population

Hospitalized patients that underwent a thoracic CT-scan

Description

Inclusion Criteria:

  • patient with insurance covering
  • patient admitted to the participating hospitals for SARS-CoV-2 infection or postoperative acute hypoxemic respiratory failure between 01/01/2019 and 05/11/2020

Exclusion Criteria:

- patient transferred to another hospital than the participating center during the 7 days following the CT scan

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Retrospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Patients with SARS-CoV-2 infection
Automated measurement
Patients with Postoperative hypoxemic respiratory failure
Automated measurement

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Correlation between altered pulmonary volume and ordinal severity scale
Time Frame: 2 days after CT scan
2 days after CT scan

Secondary Outcome Measures

Outcome Measure
Time Frame
Correlation between altered pulmonary volume and ordinal severity scale
Time Frame: 7 days after CT scan
7 days after CT scan

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 1, 2020

Primary Completion (Anticipated)

March 1, 2024

Study Completion (Anticipated)

March 1, 2024

Study Registration Dates

First Submitted

August 26, 2020

First Submitted That Met QC Criteria

August 26, 2020

First Posted (Actual)

September 1, 2020

Study Record Updates

Last Update Posted (Actual)

April 18, 2023

Last Update Submitted That Met QC Criteria

April 14, 2023

Last Verified

April 1, 2023

More Information

Terms related to this study

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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