- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05327179
Effects of Action Observation Therapy and Video-Based Play Therapy on Children With Unilateral Cerebral Palsy
Effects of Action Observation Therapy and Video-Based Play Therapy on the Upper Extremity and Trunk in Children With Unilateral Cerebral Palsy in the Framework of the International Classification of Functioning, Disability, and Health
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Cerebral Palsy (CP) defines a group of permanent disorders in the development of movement and posture that occur in the developing fetal and newborn brain, due to non-progressive disorders, leading to activity limitations. Unilateral CP (uCP) accounts for 38% of cases. These children complain of motor and sensory disorders that are more prominent on one side of the body, usually in the upper extremity (UE). These sensorimotor disorders typically limit their ability to perform activities of daily living, negatively affecting participation and quality of life. Therefore, in the last ten years, research on UE interventions for children with uCP has been focused on; While trying to develop existing methods, new treatment methods are tried to be created. There are various treatment modalities that aim to relieve UE function disorders and reduce activity limitations. It is very important to determine the most effective treatment method. However, there are few randomized controlled studies measuring clinical outcomes in children with uCP. New intervention strategies based on sound methodological and scientific foundations are needed.
It has been reported that motor learning is the basis of UE treatments applied in CP and reported to be effective. Based on neurophysiological findings, there are studies suggesting that AOT and VR treatment approaches accelerate the motor learning process. AOT; It includes observing selected UE actions and actively imitating the observed action. AOT has been previously used in the treatment of upper extremity in patients with chronic stroke, recovery of frostbite phenomenon in Parkinson's disease, treatment of lower and upper extremities in pediatric rehabilitation, and recovery of limb function after orthopedic surgery and has been reported in studies. Recent studies, especially in children with uCP, have reported promising results. In general, telerehabilitation is an effective, flexible, personalized and relatively cost-effective intervention, which strengthens the hypothesis that home rehabilitation services are a viable alternative to routine care. AOT can be easily performed at home as it is an approach based on careful observation and active imitation of actions. approach has been reported. Studies have reported that VR improves posture, balance, upper extremity function, and trunk control. There is no study in the literature examining the effects of motor learning-based AOT and VR applied at home on UE and body within the framework of international functionality, disability and health classification. Within the scope of the study, a contribution will be made to the literature, which has been reported to be insufficient in studies on UE treatments.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: sinem erturan, MSc
- Phone Number: +905388557084
- Email: snm.ertrn@gmail.com
Study Contact Backup
- Name: Bülent elbasan, prof
- Phone Number: +905324672923
- Email: bulentelbasan@gmail.com
Study Locations
-
-
None Selected
-
Ankara, None Selected, Turkey, 06500
- Gazi University
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- The clinical type is spastic hemiparetic CP.
- Upper extremity spasticity value between 0 and 3 according to Modified Ashworth.
- To have the cognitive level to understand simple instructions.
- It is largely the absence of auditory and visual loss.
Exclusion Criteria:
- Not volunteering to participate in the study.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Group 1
Action Observation Treatment
|
Action Observation Treatment program will be applied to the group 1 for 3 weeks, 5 days a week, 30 minutes a day.
In the videos prepared, activities including daily life activities for the wrist, elbow and shoulder (emptying water from the glass, throwing sugar into the glass, painting, using clothespins, spoons, etc.) will be included.
|
Experimental: Group 2
Virtual Rehabilitation
|
Virtual Rehabilitation program will be applied to the group 2 for 3 weeks, 5 days a week, 30 minutes a day.
Among the games, games that will improve daily life activities for the wrist, elbow and shoulder (steering wheel, popping balloons, touching the aquarium, etc.) will be selected.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Sociodemographic Data Form
Time Frame: Before starting treatment
|
Information such as gender, age, clinical type, extremity involvement, dominant extremity, birth weight, assistive devices used of the cases will be recorded in the prepared sociodemographic data form
|
Before starting treatment
|
Joint Range of Motion (ROM) Measurement
Time Frame: Before starting treatment
|
Individuals' ROM degrees will be evaluated before and after the treatment using a universal goniometer in the supine position.
Individuals' shoulder flexion, abduction, internal and external rotation, elbow and wrist flexion and extension painless active ROM measurements will be evaluated and recorded bilaterally.
|
Before starting treatment
|
Pediatric Quality of Life Inventory
Time Frame: Before starting treatment
|
The Pediatric Quality of Life Inventory (PedsQL™) is a modular instrument for measuring health-related quality of life dimensions in children and adolescents ages 2-18 years.
The PedsQL™ 4.0 Generic Core Scales are multidimensional (physical, emotional, social, school/role functioning) child self-report and parent proxy report scales developed as a generic measure to be integrated with the PedsQL™ disease-specific modules.
|
Before starting treatment
|
The Jebsen Hand Function Test
Time Frame: Before starting treatment
|
The Jebsen Hand Function Test (JHFT) was developed to provide a standardized and objective evaluation of fine and gross motor hand function using simulated activities of daily living. It has 7 items and takes approximately 15-45 minutes to administer. Item 1: Writing, Item 2: Card Turning, Item 3: Small Common Objects, Item 4: Simulated feeding, Item 5: Checkers, Item 6: Large Light Object, Item 7: Large Heavy Objects |
Before starting treatment
|
ABILHAND-Kids
Time Frame: Before starting treatment
|
ABILHAND-Kids is a measure of manual ability for children with upper limb impairments. The scale measures a person's ability to manage daily activities that require the use of the upper limbs, whatever the strategies involved. The ABILHAND-Kids questionnaire assesses manual ability as a test focused on the child's difficulty perceived by the child's parents. The questionnaire was developed using the Rasch measurement model which provides a method to convert the raw scores into a linear measure located on a unidimensional scale. ABILHAND-Kids has been calibrated in children with cerebral palsy according to the difficulty of children in performing manual activities as perceived by their parents. |
Before starting treatment
|
The Quality of Upper Extremity Skills Test
Time Frame: Before starting treatment
|
The Quality of Upper Extremity Skills Test is an outcome measure designed to evaluate movement patterns and hand function in children with cerebral palsy.
The QUEST is both reliable and valid.
There are 36 items that evaluate dissociated movements, grip, protective extension, and weight bearing
|
Before starting treatment
|
Selective Control of the Upper Extremity Scale
Time Frame: Before starting treatment
|
This test was developed to evaluate the selective motor control of the upper extremity.
It is a very practical and useful video-based assessment tool that can be applied in less than 15 minutes.
No special equipment is required other than a video camera.
It offers the opportunity to evaluate the selective movements of the shoulder, elbow, forearm, wrist and fingers for both right and left extremities.
The person administering the test passively shows the participant the movements they are asked to do.
Then the participant is asked to actively perform the movement shown.
While performing the participant movements; Head, trunk and other extremity movements are taken with a video camera to provide the opportunity to observe.
The degree of selective motor control is determined as 0-3 points for each joint, depending on the person's ability to perform movements and their shape.
|
Before starting treatment
|
Trunk Control Measurement Scale
Time Frame: Before starting treatment
|
The Trunk Control Measurement Scale (TCMS) was used to evaluate the trunk control of the individuals participating in the study.
The TCMS includes 15 items that measure static and dynamic sitting balance, the two main components of trunk control.
The Static Sitting Balance Scale (item 1-5) evaluates the ability to maintain a stable trunk posture during movements of the upper and lower extremities.
The Dynamic Sitting Balance Scale (item 6-15) is divided into two subscales, the selective movement control scale and the dynamic reaching scale.
The total score is between 0-58.
A higher score indicates better performance.
|
Before starting treatment
|
Gross grip strength
Time Frame: Before starting treatment
|
The Association of American Handheld Runners (AAHR) set a standard position to measure hand grip strength.
According to the standard position; The patient will be in a sitting position, shoulders in adduction, elbows in 90 degrees flexion, and forearm and wrist in neutral position.
The unit of grip force will be accepted as Newton.
|
Before starting treatment
|
Pinch force
Time Frame: Before starting treatment
|
Pinch force was evaluated using a pinchmeter.
In cases; Type, lateral and triple grip measurements will be made.
The measurement position is recommended by the American Association of Hand Therapists; the shoulder will be in adduction and rotation-neutral position, the elbow will be in 90-degree flexion, and the forearm and wrist will be in neutral position.
These conditions will be provided while the patient is in a sitting position.
|
Before starting treatment
|
Childhood Health Assessment Questionaire
Time Frame: Before starting treatment
|
CHAQ; It consists of 8 subsections and 30 questions: dressing and personal care, standing up, eating, walking, body care, reaching, holding, activities.
In addition, the use of assistive devices, devices, pain and well-being are questioned.
A separate and total score is calculated for each subsection.
Each question is evaluated as no difficulty: 3, with some difficulty: 2, with great difficulty: 1, unable to do: 0 points.
In our study, the cases in both groups will be evaluated with CHAQ.
|
Before starting treatment
|
Sociodemographic Data Form
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
Information such as gender, age, clinical type, extremity involvement, dominant extremity, birth weight, assistive devices used of the cases will be recorded in the prepared sociodemographic data form
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Joint Range of Motion (ROM) Measurement
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
Individuals' ROM degrees will be evaluated before and after the treatment using a universal goniometer in the supine position.
Individuals' shoulder flexion, abduction, internal and external rotation, elbow and wrist flexion and extension painless active ROM measurements will be evaluated and recorded bilaterally.
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Pediatric Quality of Life Inventory
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
The Pediatric Quality of Life Inventory (PedsQL™) is a modular instrument for measuring health-related quality of life dimensions in children and adolescents ages 2-18 years.
The PedsQL™ 4.0 Generic Core Scales are multidimensional (physical, emotional, social, school/role functioning) child self-report and parent proxy report scales developed as a generic measure to be integrated with the PedsQL™ disease-specific modules.
|
After 3 weeks of treatment (treatment is 15 sessions)
|
The Jebsen Hand Function Test
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
The Jebsen Hand Function Test (JHFT) was developed to provide a standardized and objective evaluation of fine and gross motor hand function using simulated activities of daily living. It has 7 items and takes approximately 15-45 minutes to administer. Item 1: Writing, Item 2: Card Turning, Item 3: Small Common Objects, Item 4: Simulated feeding, Item 5: Checkers, Item 6: Large Light Object, Item 7: Large Heavy Objects |
After 3 weeks of treatment (treatment is 15 sessions)
|
ABILHAND-Kids
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
ABILHAND-Kids is a measure of manual ability for children with upper limb impairments. The scale measures a person's ability to manage daily activities that require the use of the upper limbs, whatever the strategies involved. The ABILHAND-Kids questionnaire assesses manual ability as a test focused on the child's difficulty perceived by the child's parents. The questionnaire was developed using the Rasch measurement model which provides a method to convert the raw scores into a linear measure located on a unidimensional scale. ABILHAND-Kids has been calibrated in children with cerebral palsy according to the difficulty of children in performing manual activities as perceived by their parents. |
After 3 weeks of treatment (treatment is 15 sessions)
|
The Quality of Upper Extremity Skills Test
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
The Quality of Upper Extremity Skills Test is an outcome measure designed to evaluate movement patterns and hand function in children with cerebral palsy.
The QUEST is both reliable and valid.
There are 36 items that evaluate dissociated movements, grip, protective extension, and weight bearing
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Selective Control of the Upper Extremity Scale
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
This test was developed to evaluate the selective motor control of the upper extremity.
It is a very practical and useful video-based assessment tool that can be applied in less than 15 minutes.
No special equipment is required other than a video camera.
It offers the opportunity to evaluate the selective movements of the shoulder, elbow, forearm, wrist and fingers for both right and left extremities.
The person administering the test passively shows the participant the movements they are asked to do.
Then the participant is asked to actively perform the movement shown.
While performing the participant movements; Head, trunk and other extremity movements are taken with a video camera to provide the opportunity to observe.
The degree of selective motor control is determined as 0-3 points for each joint, depending on the person's ability to perform movements and their shape.
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Trunk Control Measurement Scale
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
The Trunk Control Measurement Scale (TCMS) was used to evaluate the trunk control of the individuals participating in the study.
The TCMS includes 15 items that measure static and dynamic sitting balance, the two main components of trunk control.
The Static Sitting Balance Scale (item 1-5) evaluates the ability to maintain a stable trunk posture during movements of the upper and lower extremities.
The Dynamic Sitting Balance Scale (item 6-15) is divided into two subscales, the selective movement control scale and the dynamic reaching scale.
The total score is between 0-58.
A higher score indicates better performance.
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Gross grip strength
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
The Association of American Handheld Runners (AAHR) set a standard position to measure hand grip strength.
According to the standard position; The patient will be in a sitting position, shoulders in adduction, elbows in 90 degrees flexion, and forearm and wrist in neutral position.
The unit of grip force will be accepted as Newton.
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Pinch force
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
Pinch force was evaluated using a pinchmeter.
In cases; Type, lateral and triple grip measurements will be made.
The measurement position is recommended by the American Association of Hand Therapists; the shoulder will be in adduction and rotation-neutral position, the elbow will be in 90-degree flexion, and the forearm and wrist will be in neutral position.
These conditions will be provided while the patient is in a sitting position.
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Childhood Health Assessment Questionaire
Time Frame: After 3 weeks of treatment (treatment is 15 sessions)
|
CHAQ; It consists of 8 subsections and 30 questions: dressing and personal care, standing up, eating, walking, body care, reaching, holding, activities.
In addition, the use of assistive devices, devices, pain and well-being are questioned.
A separate and total score is calculated for each subsection.
Each question is evaluated as no difficulty: 3, with some difficulty: 2, with great difficulty: 1, unable to do: 0 points.
In our study, the cases in both groups will be evaluated with CHAQ.
|
After 3 weeks of treatment (treatment is 15 sessions)
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: sinem erturan, MSc, bulentelbasan@gmail.com
Study record dates
Study Major Dates
Study Start (Anticipated)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 2020 - 698
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
product manufactured in and exported from the U.S.
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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