Work-To-Rest Ratios

The purpose of the study is to compare physiological responses to two hours of work adhering to two variations of a work-to-rest ratio in a hot environment.

Study Overview

• Status: Completed
• Conditions: Hyperthermia
• Intervention / Treatment: Other: Work to rest cycles of 40:20 minutes; Other: Work to rest cycles of 20:10 minutes

• Study Type: Interventional
• Enrollment (Actual): 15
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • New York
    • Buffalo, New York, United States, 14214
      • University at Buffalo

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 39 years (Adult)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Healthy 18-39 year old individuals
• Physically active

Exclusion Criteria:

• History of cardiovascular, metabolic, respiratory, neural, or renal disease
• Hypertensive or tachycardic during the screening visit (systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, resting heart rate ≥ 100 bpm)
• Taking medication or supplements with a known side effect of affecting physiologic responses to exercise (e.g., acetaminophen, beta blockers, statins, aspirin)
• Any form of tobacco or nicotine use in the past six months
• Current musculoskeletal injury impacting physical activity
• A positive pregnancy test at any point in the study
• Study physician discretion based on any other medical condition or medication

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: 40:20; Walking for 40 minutes, resting for 20	Other: Work to rest cycles of 40:20 minutes; Walking in a hot environment for 2 hours with repeated 40 minutes of work and 20 minutes of rest
Experimental: 20:10; Walking for 40 minutes, resting for 20	Other: Work to rest cycles of 20:10 minutes; Walking in a hot environment for 2 hours with repeated 20 minutes of work and 10 minutes of rest

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in core body temperature	Core body temperature is measured using a rectal thermistor	Upon completion of 2 hours of the work protocol
Change in heart rate	Heart rate is measured using a telemetry strap	Upon completion of 80 minutes of work

Collaborators and Investigators

• Sponsor: State University of New York at Buffalo
• Investigators: Principal Investigator: Riana Pryor, PhD, University at Buffalo

Study record dates

Study Major Dates

• Study Start (Actual): March 21, 2022
• Primary Completion (Actual): November 5, 2023
• Study Completion (Actual): November 5, 2023

Study Registration Dates

• First Submitted: March 26, 2022
• First Submitted That Met QC Criteria: April 7, 2022
• First Posted (Actual): April 14, 2022

Study Record Updates

• Last Update Posted (Estimated): November 9, 2023
• Last Update Submitted That Met QC Criteria: November 8, 2023
• Last Verified: November 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Wounds and Injuries; Body Temperature Changes; Heat Stress Disorders; Hyperthermia
• Other Study ID Numbers: STUDY00006115

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: We do not plan to share these data with other researchers.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No