Risk Factors for the Occurrence of Post Intensive Care Syndrome (PICS) (PICS3)

Risk Factors for the Occurrence of Post Intensive Care Syndrome (PICS) At 3 Months After a Stay in the Rangueil Multipurpose Resuscitation Unit of the Toulouse University Hospital

Monocentric, observational, descriptive RIPH3 study with prospective data collection.

Study Overview

• Status: Completed
• Conditions: Post Intensive Care Syndrome
• Intervention / Treatment: Diagnostic test: A consultation

Detailed Description

A consultation in the form of a teleconsultation with video conference is proposed to all adult patients who have stayed more than 24 hours in the Rangueil intensive care unit.

This consultation is scheduled and will take place approximately three months after the end of the stay in the intensive care unit.

During this consultation, signs will be sought through questioning to detect or even diagnose the presence of a PICS.

We will also look for elements that will allow us to characterize people with CHIP.

If a PICS was detected during the consultation, the summary letter sent to the attending physician informs him/her of

1. The presence of a CHIP in his patient
2. The nature of this CHIP (CHIP with a purely psychological component, CHIP with a psychological and physical component, etc.) In this same summary letter, the attending physician will be offered a list of specialists practicing at the CHU who are likely to take charge of the patient's CHIP.

• Study Type: Observational
• Enrollment (Actual): 97

Contacts and Locations

Study Locations

• France
  • Toulouse, France
    • University Hospital of Toulouse

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

population of patients surviving a stay in polyvalent resuscitation

Description

Inclusion Criteria:

• adult patient
• hospitalized in the intensive care unit of Rangueil of the TOULOUSE University Hospital
• length of stay in intensive care equal or superior to 24 hours
• affiliated to a social security system
• having expressed no objection to participate in the study

Exclusion Criteria:

• minor patient
• no consent to the study
• patient not capable of expressing his "non opposition" to the study
• patient under guardianship, curatorship or safeguard of justice

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Incidence at 3 months of PICS	Incidence at 3 months of PICS as defined below: A PICS is defined as ''present'' at the 3-month visit if the patient has one or more of the following: Impaired quality of life as defined by a 5D5L EQ score greater than or equal to 3 on at least 1 dimension of the questionnaire.; Anxiety symptoms defined by a HADS anxiety score greater than or equal to 11.; Depressive symptoms defined by a HADS depression score greater than or equal to 11.; Symptoms of post-traumatic stress defined by a PCL 5 score greater than or equal to 33.; Symptoms of undernutrition defined by an NRS score greater than or equal to 3.; Pain symptoms defined by a DN4 score greater than or equal to 4 and/or an EVS score greater than or equal to 4.	month 3

Collaborators and Investigators

• Sponsor: University Hospital, Toulouse

Study record dates

Study Major Dates

• Study Start (Actual): October 10, 2022
• Primary Completion (Actual): June 30, 2023
• Study Completion (Actual): June 30, 2023

Study Registration Dates

• First Submitted: September 6, 2022
• First Submitted That Met QC Criteria: September 6, 2022
• First Posted (Actual): September 10, 2022

Study Record Updates

• Last Update Posted (Actual): September 25, 2024
• Last Update Submitted That Met QC Criteria: September 23, 2024
• Last Verified: September 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Disease; Syndrome
• Other Study ID Numbers: RC31/22/0215; 2022-A01371-42 (Other Identifier: ID-RCB)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No