- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06078241
Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
November 16, 2023 updated by: Ibrahim Mamdouh Esmat, Ain Shams University
Intravenous Lidocaine Infusion Versus Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure to remove stones from the kidney by a small puncture wound through the skin.
Patients receiving lidocaine infusion had lower pain scores, reduced postoperative analgesic requirements and decreased intraoperative anesthetic requirements.
Erector spinae plane block (ESPB) seems to be effective when compared with no block or a placebo block.
Study Overview
Status
Recruiting
Conditions
Study Type
Interventional
Enrollment (Estimated)
150
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Ibrahim Mamdouh Esmat
- Phone Number: 01001241928
- Email: ibrahim_mamdouh@med.asu.edu.eg
Study Locations
-
-
-
Cairo, Egypt
- Recruiting
- Ain-Shams University Hospitals
-
Contact:
- Ibrahim Mamdouh Esmat
- Email: ibrahim_mamdouh@med.asu.edu.eg
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- American Society of Anesthesiologists (ASA) score I-II..
- Body mass index < 35 kg/m2.
Exclusion Criteria:
- Patient's refusal.
- Known coagulopathy.
- Known peripheral neuropathy or neurological deficits.
- Chronic pain disorders.
- Known allergy to study drugs
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: Erector spinae plane block (ESPB)
|
Unilateral erector spinae plane block
|
Active Comparator: Intravenous lidocaine infusion
|
Intravenous lidocaine infusion
|
Placebo Comparator: Intravenous infusion of normal saline and ESPB with normal saline
|
Intravenous infusion of normal saline
Unilateral ESPB with normal saline
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Time to first rescue analgesia
Time Frame: 24 hours postoperatively
|
Time to first rescue analgesia
|
24 hours postoperatively
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
November 1, 2023
Primary Completion (Estimated)
April 30, 2024
Study Completion (Estimated)
April 30, 2024
Study Registration Dates
First Submitted
October 5, 2023
First Submitted That Met QC Criteria
October 5, 2023
First Posted (Actual)
October 11, 2023
Study Record Updates
Last Update Posted (Estimated)
November 17, 2023
Last Update Submitted That Met QC Criteria
November 16, 2023
Last Verified
November 1, 2023
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Nervous System Diseases
- Neurologic Manifestations
- Neurobehavioral Manifestations
- Perceptual Disorders
- Agnosia
- Physiological Effects of Drugs
- Molecular Mechanisms of Pharmacological Action
- Anti-Arrhythmia Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
- Anesthetics
- Membrane Transport Modulators
- Anesthetics, Local
- Voltage-Gated Sodium Channel Blockers
- Sodium Channel Blockers
- Lidocaine
Other Study ID Numbers
- FMASU MS 556/ 2023
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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