Impact of the CRRT Management Protocol on Prognostic Outcome in Patients With Septic Acute Kidney Injury

October 8, 2023 updated by: Xiemuziya Maimaitirexiati, Xinjiang Medical University

Xinjiang Medical University of Affiliated Tumour Hospital

The implementation of CRRT nursing team management program in the treatment of SAKI can significantly reduce the incidence of adverse events and complications in CRRT nursing, which has a positive role in improving the success rate of CRRT treatment and the clinical outcome of patients.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

76

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Xinjiang
      • Urumqi, Xinjiang, China, 830011
        • Xinjiang Medical University of Affiliated tumour Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

36 SAKI patients who were treated with CRRT in ICU of our hospital from February 2021 to August 2021 were set as the control group, and the routine bedside CRRT nursing management process was implemented in this stage; In addition, from September 2021 to March 2022, 40 SAKI patients who received CRRT treatment in our ICU were set as the observation group.The management plan of CRRT special nursing team was implemented to compare the incidence of non planned removal of CRRT, unplanned extubation and CRRT nursing related complications between the two groups, as well as the difference of coagulation function indexes before and 3 days after nursing.

Description

Inclusion Criteria:

  • The Guidelines for Emergency Treatment of Sepsis / Septic Shock in China (2018)[4]Diagnostic criteria for moderate sepsis; ② meets the Organization for Improving Global Kidney Disease Outcomes (KDIGO) Clinical Practice Guidelines: AKI[5]Relevant diagnostic criteria in; ③ received CRRT as indicated for CRRT; ④ in ICU for longer than 24 hours; ⑤ signed consent.

Exclusion Criteria:

  • with chronic organ failure, or advanced malignancy; ② with previous history of chronic kidney disease, retrorenal urinary tract obstruction; ③ with incomplete clinical data.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Control group
Observation group
Other: Implement the CRRT specialist nursing group management program on the basis of routine care
Training the department nurses on CRRT related theoretical knowledge and operation skills; guiding the process of CRRT different treatment modes, solving CRRT nursing problems, evidence-based nursing guidance; consulting CRRT treatment and nursing related treatment, timely understanding the new progress; responsible for CRRT nursing quality control, etc.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
To explore the influence of CRRT nursing team management plan on the prognosis of SAKI patients.
Time Frame: 3-10 days
The incidence of unplanned removal of CRRT, unplanned extubation and CRRT nursing related complications in the observation group were lower than those in the control group (P <0.05). Kaplan Meier survival curve showed that the survival rate of patients in the observation group was higher than that in the control group (P <0.05).
3-10 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Xinjiang Medical University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 1, 2021

Primary Completion (Actual)

May 1, 2023

Study Completion (Actual)

June 7, 2023

Study Registration Dates

First Submitted

October 8, 2023

First Submitted That Met QC Criteria

October 8, 2023

First Posted (Actual)

October 13, 2023

Study Record Updates

Last Update Posted (Actual)

October 13, 2023

Last Update Submitted That Met QC Criteria

October 8, 2023

Last Verified

October 1, 2023

More Information

Terms related to this study

Other Study ID Numbers

  • XMaimaitirexiati

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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