Effect of Aerobic Training on Quality of Life in Elderly With Idiopathic Chronic Fatigue

February 9, 2024 updated by: Ola Mohamed Elsayed Elgohary, Pharos University in Alexandria
the study was conducted to evaluate the effectiveness of aerobic training for decreasing fatigue severity and increasing quality of life in elderly with idiopathic chronic

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

idiopathic chronic fatigue (ICF) or chronic idiopathic fatigue (CIF), this type of tiredness is ongoing and unrelated to any underlying medical or mental health issues. Different diagnostic criteria apply to people with idiopathic chronic fatigue and those with chronic fatigue syndrome (CFS).

Regular aerobic exercise has been demonstrated to improve cardiopulmonary fitness, increase physical activity levels, and decrease the degree of fatigue in elderly patients with severe idiopathic fatigue.

Study Type

Interventional

Enrollment (Estimated)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

inclusion criteria:

  • ages ranged from 60 to 70 years and they will have BMI in between25.0-29.9 kg/m2,
  • complaining fatigue least six months ago without identifying any specific cause for their fatigue.
  • could walk safely without the aid of another person.

Exclusion Criteria:

  • Renal, vascular, hepatic, autoimmune, heart, chest and thyroid disorders.
  • Lower limb arthritis or any orthopedic problem will hinder the training.
  • Cognitive impairment or psychological problems,
  • fatigue caused as a known side effect of medication.
  • any febrile condition and/or infectious diseases

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: control group (group B)
twenty participants have idiopathic chronic fatigue will received only traditional physical therapy exercise program (flexibility and balance activities)
Other: Aerobic training
In addition to the standard physical therapy exercise programme (which includes flexibility and balance exercises), twenty individuals with idiopathic chronic fatigue will participate in an aerobic training group and walk for 45 minutes on a treadmill three times a week for two months. The workouts began with a five- to ten-minute warm-up on the treadmill and concluded with an equally extended cool-down. Using the Karvonen method, for exercise intensities range from 60 to 75 percent of heart rate reserve during a 35-minute group cumulative exercise session.
Other Names:
  • traditional physical therapy exersise program
Experimental: Aerobic training (group a)
In addition to the standard physical therapy exercise programme (which includes flexibility and balance exercises), twenty individuals with idiopathic chronic fatigue will participate in an aerobic training group and walk for 45 minutes on a treadmill three times a week for two months. The workouts began with a five- to ten-minute warm-up on the treadmill and concluded with an equally extended cool-down. Using the Karvonen method, for exercise intensities ranging from 60 to 75 per cent of heart rate reserve during a 35-minute group cumulative exercise session.
Other: Aerobic training
In addition to the standard physical therapy exercise programme (which includes flexibility and balance exercises), twenty individuals with idiopathic chronic fatigue will participate in an aerobic training group and walk for 45 minutes on a treadmill three times a week for two months. The workouts began with a five- to ten-minute warm-up on the treadmill and concluded with an equally extended cool-down. Using the Karvonen method, for exercise intensities range from 60 to 75 percent of heart rate reserve during a 35-minute group cumulative exercise session.
Other Names:
  • traditional physical therapy exersise program

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Older People's Quality of Life Questionnaire (OPQOL-brief):
Time Frame: 2 monthes will take pre and post total study peroid
Thirteen items make up the questionnaire; one item includes codes of Strongly agree (1), Agree (2), Neither (3), Disagree (4), and Strongly disagree (5). Positive items are reverse coded to indicate higher quality of life (QoL) with higher scores once all of the questions have been added up to give an overall OPQOL-Brief score.
2 monthes will take pre and post total study peroid
fatigue severity assessment scale
Time Frame: 2 month will take pre and post total study peroid
Before and during the study period, the physical and mental weariness of both groups (A and B) was measured using a straightforward ten-item fatigue scale. The participants rated an etch statement from five categories, from never to always, using a scale. 1 denotes never, 2 occasionally, 3 regularly, 4 often and 5 always worn out. The greater figure denotes an extremely high degree of exhaustion and fatigue.
2 month will take pre and post total study peroid
six mints walk test
Time Frame: 2 monthes will take pre and post total study peroid
Before and during the study period, the aerobic capacity and endurance of both groups (A and B) were assessed using this sub-maximal test. The outcomes were compared to see how the performance capacity changed with walks lasting longer than six minutes.
2 monthes will take pre and post total study peroid
Glutathione blood test:
Time Frame: 2 monthes will take pre and post total study peroid
Glutathione is an antioxidant, a type of chemical which helps to boost the immune system as well as prevent and reverse cellular damage. Glutathione levels tend to decrease naturally with age as well as due to health conditions such as liver disease, insomnia, and chronic disease.Before and after the study period, venous blood was taken from both groups (A and B) at baseline when they were not fasting. Tandem mass spectroscopy was used to analyse the samples and determine the degree of serum changes in both study groups based on their respective treatment.
2 monthes will take pre and post total study peroid

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Glutathione blood test:
Time Frame: 2 monthes will take pre and post total study peroid
Glutathione is an antioxidant, a type of chemical which helps to boost immune system as well as prevent and reverse cellular damage. Glutathione levels tend to decrease naturally with age as well as due to health conditions such as liver disease, insomnia, and chronic disease.
2 monthes will take pre and post total study peroid

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Pharos University in Alexandria

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

February 10, 2024

Primary Completion (Estimated)

April 13, 2024

Study Completion (Estimated)

May 7, 2024

Study Registration Dates

First Submitted

December 11, 2023

First Submitted That Met QC Criteria

December 26, 2023

First Posted (Actual)

January 12, 2024

Study Record Updates

Last Update Posted (Estimated)

February 13, 2024

Last Update Submitted That Met QC Criteria

February 9, 2024

Last Verified

December 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • aerobic training and fatigue

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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