Burn Injuries During COVID-19 Pandemic and Its Influence on Length of Stay

Anesthetic Experience and Patients 'Prognosis of SARS-CoV-2 Positive Versus Negative Burns Patients: An Observational Case -Control Study

Burn injuries were thought to be difficult to treat during the new corona virus epidemic. Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.

Study Overview

• Status: Completed
• Conditions: SARS-CoV-2 Infection
• Intervention / Treatment: Procedure: Burn Injuries Graft Surgery

Detailed Description

1. Introduction / History

The world is being attacked by the rapidly expanding severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) epidemic, which is exacerbating an economic crisis. SARS-Cov-2 is the cause of the coronavirus disease 2019 (COVID-19). Anaesthetists are at risk for contracting a virus while doing their regular duties because they frequently come into touch with respiratory droplets.

All nations have put protective and preventive measures in place, forcing people to spend more time at home. A Brazilian study discovered that during the COVID-19 pandemic period, spending more time at home increased exposure to sanitizing products, which include ethanol and hydrogen peroxides that can cause burn injuries.

Aim of our Study:

Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.

Inclusion Criteria:

Patients who had the burn graft surgery at Al Wakrah Hospital; Hamad Medical Corporation between from 1st of April to end of November 2020. Planned number will include all COVID-19 positive and negative subjects in this period.

Data Source The electronic medical record (Cerner) used in order to identify patients who match study defined criteria. The investigators can Collect data directly from Cerner to excel sheet

Variable Abstraction Patient demographic and clinical data will be collected including age, morbidities, presenting symptoms, physical examination, laboratory investigations, intraoperative data, type of surgery, postoperative course, survival, and length of hospital stay and follow up.

In addition, the type of anesthesia is also included as factor for further complications ex general anesthesia, spinal or combined spinal epidural type.

Observation full reviewing of their medical illness and chart laboratory and investigations will be collected after getting approval of MRC and IRB committee.

• Study Type: Observational
• Enrollment (Actual): 70

Contacts and Locations

Study Locations

• Qatar
  • Doha, Qatar, 82228
    • HAMAD Medical Corporation- Al Wakra Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients who had the burn graft surgery at Al Wakrah Hospital; Hamad Medical Corporation between from 1st of April to end of November 2020. Planned number will include all COVID-19 positive and negative.

Description

Inclusion Criteria:

• All burn injuries required surgery with COVID-19 positive or negative status

Exclusion Criteria:

• Other surgery during COVID-19 pandemic

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
COVID-19 Positive and Negative status; Burn injuries with COVID-19 Positive and Negative status underwent surgery	Procedure: Burn Injuries Graft Surgery; Burn Injuries Graft Surgery

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.	Our goal is to determine the risk factors that influence length of hospital stay (LOS) of burn injured patients during COVID -19 pandemic.	60-90 days

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Clinical diffreneces between burn injuries with positive vs negative COVID-19 status	Details for those risk Factors: BMI; Pre Op Lab data, Intra Op data ex. blood loss / ml, transfusions/ ml or Unit , surgery time/ min, etc, Post operative data and ICU admission data, , lab parameters, INR,LFTs/unit , required blood transfusions/ml or Unit , re intubation times, vasopressor needs. Analyze lab values /unit, check number of days in hospital stay and ICU stay . Analyze risk factors which affect hospital length of stay. Analyze risk factors using cox regression and investigate hazard ratio for each one to determine which is independent risk factor OR associated factor.	60-90 days

Collaborators and Investigators

• Sponsor: Hamad Medical Corporation

Study record dates

Study Major Dates

• Study Start (Actual): April 1, 2020
• Primary Completion (Actual): March 1, 2021
• Study Completion (Actual): June 25, 2021

Study Registration Dates

• First Submitted: August 4, 2021
• First Submitted That Met QC Criteria: March 21, 2024
• First Posted (Actual): March 26, 2024

Study Record Updates

• Last Update Posted (Actual): March 26, 2024
• Last Update Submitted That Met QC Criteria: March 21, 2024
• Last Verified: June 1, 2021

More Information

Terms related to this study

• Keywords: SARS-CoV-2; Perioperative; outcome; burn; Length of stay
• Additional Relevant MeSH Terms: Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Virus Diseases; Infections; Respiratory Tract Infections; Respiratory Tract Diseases; Pneumonia, Viral; Pneumonia; Lung Diseases; COVID-19
• Other Study ID Numbers: MRC-01-20-1074

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No