CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma

March 28, 2024 updated by: Fengchan Xi, Jinling Hospital, China

CT-based Model for Predicting Prolonged Weaning From Mechanical Ventilation in Patients With Abdominal Trauma: a Retrospective Cohort Study

Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications. However, there is currently a lack of an effective tool to predict weaning time in critically ill patients. This retrospective study established an effective nomogram model for predicting the time of weaning from mechanical ventilation in abdominal trauma patients by considering multiple perspectives. The model has been validated and demonstrated good performance in terms of discrimination, calibration, and clinical utility. Moreover, the model can effectively predict the prognosis of critically ill patients. The findings of this study have important implications for guiding respiratory management in clinically critically ill patients, particularly trauma patients.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

1023

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Jiangsu
      • Nanjing, Jiangsu, China, 210002
        • the General Surgical Department of Jinling Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Non-Probability Sample

Study Population

Patients with abdominal trauma admitted to the General Surgical Department of Jinling Hospital from January 2010 to April 2023 were screened for eligibility.

Description

Inclusion Criteria:

  • (1) with information on survival status and time;
  • (2) aged 18-80 years;
  • (3) admitted to ICU;
  • (4) with abdominal CT performed within 1-week post-trauma;
  • (5) use of mechanical ventilation.

Exclusion Criteria:

  • (1) low-quality CT images;
  • (2) history of mental illness.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Prolonged mechanical ventilation
Time Frame: through whole hospitalization of each participant, an average of 25 days
Prolonged mechanical ventilation was defined as length of mechanical ventilation >7 days
through whole hospitalization of each participant, an average of 25 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Jinling Hospital, China

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 1, 2023

Primary Completion (Actual)

December 15, 2023

Study Completion (Actual)

February 5, 2024

Study Registration Dates

First Submitted

March 24, 2024

First Submitted That Met QC Criteria

March 28, 2024

First Posted (Actual)

April 1, 2024

Study Record Updates

Last Update Posted (Actual)

April 1, 2024

Last Update Submitted That Met QC Criteria

March 28, 2024

Last Verified

March 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2021NZKY-045-01

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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