- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06458920
Social Facilitation of Emotion Regulation in Adolescence
July 14, 2026 updated by: Jennifer Silvers, PhD, University of California, Los Angeles
The goal of this project is to test whether regulating emotions with help from a friend is more effective and long-lasting in adolescents than regulating alone, and to characterize age-related differences in the neural mechanisms supporting social versus cognitive emotion regulation.
Participants will complete a psychology experiment while undergoing fMRI scanning.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Detailed Description
Participants will complete a novel paradigm during functional magnetic resonance imaging (fMRI) to examine whether adolescents (N = 50) and adults (N = 50) are more effective at down-regulating negative affect when a friend provides them with reinterpretations of negative stimuli (i.e.
social reappraisal), as compared to when they reinterpret stimuli alone (i.e., cognitive reappraisal).
Specifically, participants will look at pictures of upsetting events while undergoing fMRI scanning.
For some pictures, they will be instructed to just look at the image.
For other pictures, they will be told to listen to their friend's voice as their friend helps them to regulate their emotions.
For other pictures, they will be told to regulate their emotions on their own.
The primary comparison of interest is how participants regulate emotion on their own versus when their friend helps them.
Study Type
Interventional
Enrollment (Estimated)
100
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
California
-
Los Angeles, California, United States, 90095
- Recruiting
- University of California, Los Angeles
-
Contact:
- Elizabeth Gaines, BA
- Phone Number: (323) 989-2557
- Email: egaines@psych.ucla.edu
-
Contact:
- Jennifer Silvers, PhD
- Phone Number: 3102069024
- Email: silvers@ucla.edu
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- Adolescent participants must be 13-15 year of age
- Adult participants must be 20-25 years of age
- Proficient in English
Exclusion Criteria:
- Auditory, visual or cognitive impairment
- Any health conditions that are contraindicated for MRI
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Social regulation
Participants will regulate emotion with the help of a friend
|
Participants will regulate emotion with the help of a friend
|
|
Experimental: Cognitive regulation
Participants will regulate emotion on their own
|
Participants will regulate emotion on their own
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Negative affect
Time Frame: 1 day
|
Participant's self-reported negative affect on 1-4 scale (1=not bad at all, 4=very bad) during experiment
|
1 day
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
October 5, 2022
Primary Completion (Estimated)
October 1, 2026
Study Completion (Estimated)
October 1, 2026
Study Registration Dates
First Submitted
June 7, 2024
First Submitted That Met QC Criteria
June 12, 2024
First Posted (Actual)
June 14, 2024
Study Record Updates
Last Update Posted (Actual)
July 16, 2026
Last Update Submitted That Met QC Criteria
July 14, 2026
Last Verified
July 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 21-000929
- R21HD108751 (U.S. NIH Grant/Contract)
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
YES
IPD Plan Description
Deidentified participant data including age, gender and negative affect
IPD Sharing Time Frame
12 months from study completion
IPD Sharing Access Criteria
Deidentified data will be posted on Open Science Framework
IPD Sharing Supporting Information Type
- STUDY_PROTOCOL
- SAP
- ANALYTIC_CODE
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.