Breathing Exercises on Lung Function

Impact of Breathing Exercises on Lung Function in Chronic Airway Diseases

aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.

Study Overview

• Status: Recruiting
• Conditions: Breathing Exercises
• Intervention / Treatment: Behavioral: Breathing exercises

Detailed Description

Breathing exercises offer numerous benefits for individuals with chronic airway diseases, such as chronic obstructive pulmonary disease (COPD), asthma and bronchiectasis. These exercises help improve respiratory function, reduce symptoms, and enhance the overall quality of life.Techniques such as diaphragmatic breathing, incentive spirometer and pursed lip breathing help patients use their lungs more effectively. Breathing exercises can enhance lung function by increasing the efficiency of the respiratory muscles and improving ventilation. Asthma is a chronic inflammatory disorder of the airways classified as intermittent or persistent (mild, moderate or severe), according to the presence of diurnal and nocturnal symptoms, necessity of medication, frequency of exacerbation, physical activity limitations and pulmonary function. All of these symptoms deteriorate in the patient's quality of life and psychological well-being and restrict daily living physical activities (DLPA). Asthma symptoms experienced during daily living physical activities (DLPA) or the fear of triggering symptoms may keep asthmatic subjects from engaging in physical exercise, and the patients tend to be less physically active and less conditioned than healthy individuals. In addition, asthmatic patients have higher levels of anxiety and depression that have been shown to be associated with an increased number of exacerbations and the diagnosis of severe asthma. These psychosocial disorders can modify the respiratory breathing pattern, which leads to irregular breathing, frequent sighing, and predominant thoracic breathing. These irregular breathing patterns increase the number of respiratory (breathlessness, chest tightness and pain) and non-respiratory symptoms (anxiety, dizziness and fatigue). Recent Global Initiative for Chronic Obstructive Pulmonary Disease guidelines (GOLD) underline the importance of pulmonary rehabilitation (PR) as a part of an integrative multidisciplinary approach regardless of the stage of disease

• Study Type: Interventional
• Enrollment (Estimated): 50
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Mohamed AbdElmoniem; Phone Number: 01014008473; Email: dr.m1993@mans.edu.eg
• Study Contact Backup: Name: Mohamed Ahmed Ibrahim

Study Locations

• Egypt
  • Mansoura, Egypt, 35516
    • Recruiting
    • Mohamed AbdElmoniem
    • Contact: Mohamed AbdElmoniem; Phone Number: 01014008473; Email: dr.m1993@mans.edu.eg
    • Principal Investigator: Mohamed AbdElmoniem, Lecturer
    • Contact: Mohamed Ahmed Ibrahim; Phone Number: 01014008473; Email: dr.m1993@mans.edu.eg
    • Sub-Investigator: Mohamed Ahmed Ibrahim, Lecturer
    • Sub-Investigator: Mohamed Rafat borham, Lecturer

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 < 80% predicated together with an FEV1/FVC <0.70confirm the presence of airflow limitation that is not fully reversible.
• COPD patients ranging from mild to severe according to GOLD [stages I-IV].
• Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).
• None of the individuals had been engaged in any exercise-training program before participating in the study.
• Optimized medical therapy according to GOLD & Global Initiative for Asthma (GINA)
• Clinically stable COPD and asthmatic patients (not suffering from a recent respiratory tract infection).
• All patients are Ex-smoker

Exclusion Criteria:

• Age <18 years.
• Pregnancy
• Current Smokers
• Patients that are incapable of exercising; unable to understand any questionnaire
• Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)
• Neuromuscular disease as Myasthenia gravis, kypho-scoliosis
• Diaphragmatic Paralysis (paralyzed diaphragm exhibiting abnormal paradoxical movement, i.e., moving in a cranial direction during inspiration).

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: Chronic airway diseases treated by medication; Chronic airway diseases treated by medication without breathing exercises
Active Comparator: Chronic airway diseases treated by medication with breathing exercises; Chronic airway diseases treated by medication and breathing exercises	Behavioral: Breathing exercises; Breathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry; Other Names: Diaphragmatic Breathing exercise; Pursued lip breathing

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Impact of breathing exercises on Forced expiratory volume on first second (FEV1) in liter	Effect of Breathing exercises on lung function using spirometry	6 months
Impact of breathing exercises on Forced vital capacity (FVC) in liter	Effect of Breathing exercises on lung function using spirometry	6 months

Collaborators and Investigators

• Sponsor: Mansoura University Hospital
• Investigators: Principal Investigator: Mohamed AbdElmoniem, Lecturer of chest medicine faculty of medicine Mansoura university

Study record dates

Study Major Dates

• Study Start (Actual): June 1, 2024
• Primary Completion (Estimated): August 10, 2025
• Study Completion (Estimated): December 10, 2025

Study Registration Dates

• First Submitted: June 13, 2024
• First Submitted That Met QC Criteria: June 21, 2024
• First Posted (Actual): June 25, 2024

Study Record Updates

• Last Update Posted (Actual): May 29, 2025
• Last Update Submitted That Met QC Criteria: May 27, 2025
• Last Verified: May 1, 2025

More Information

Terms related to this study

• Keywords: lung function; Breathing exercises; Chronic airway diseases
• Additional Relevant MeSH Terms: Pathologic Processes; Respiratory Tract Diseases; Respiration Disorders; Respiratory Aspiration
• Other Study ID Numbers: R.24.05.2638

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No