Comparison of Architectural and Performance Adaptations of Hip Extension Exercise Under Gravitational or Inertial Loading Conditions

August 5, 2024 updated by: Rodrigo Martín-San-Agustin, University of Valencia
The main objective of this study is to investigate training-induced adaptations in Biceps femoris long head (BFlh) architecture and performance measures such as muscle strength, jumping, and power variables after following 6 weeks of resistance training program with gravitational or inertial hip extension (HE) exercise and a subsequent detraining period, comparing those adaptations with a control group. In addition, this study aims to determine the time course of BFlh architectural adaptations throughout a 6-week training intervention.

Study Overview

Study Type

Interventional

Enrollment (Actual)

32

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Valencia, Spain
        • Rodrigo Martin-San Agustin

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • at least two years of resistance training experience
  • not have any injury, disease or pain that could reduce their maximal effort

Exclusion Criteria:

  • history of injury to the lower limbs (including the hamstrings), wrist, or back in the past 18 months

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Gravitational
Hip extension exercise performed under gravitational loading conditions using free-weight equipment during six weeks with two sessions per week.
Hip extension exercise with gravitational load
No Intervention: Control
Participans was advised to continue their regular levels of physical activity but not to perform any lower body resistance training
Experimental: Inertial
Hip extension exercise performed under inertial loading conditions using the EPTE Inertial Concept (Ionclinics SL, L'Alcudia, Spain) during six weeks with two sessions per week. The EPTE Inertial Concept is an inertial device that combines a series of output pulleys and telescopic arms, capable of implementing 6 disks of different weights and radii.
Hip extension exercise with inertial load

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Muscle Strength Assessment
Time Frame: Baseline, at the end of the 6 weeks of training and 4 weeks after this (detraining period)
Knee flexion was assessed with subjects in prone position performing knee flexor maximal isometrics contractions with a knee angle of approximately 15 degrees. For hip extension, a resisted hip extension was requested with the subjects lying in the prone position with their legs straight. Hip adduction was evaluated in a supine position with the hips at 45º flexion, requesting an maximal isometrics contraction adduction with a resistance in the internal condyle.
Baseline, at the end of the 6 weeks of training and 4 weeks after this (detraining period)
Jump performance
Time Frame: Baseline, at the end of the 6 weeks of training and 4 weeks after this (detraining period)
CMJ and SJ, utilizing the MyJump 2 application on an iPad Pro (at 240 frames per second, high-definition video resolution). In the CMJ, participants initiated the jump from a standing position, performed a preparatory movement by bending their knees to 90° flexion, and then jumped upward as high as possible without pausing between movements. Similarly, for the SJ, participants began from a standardized position with knees flexed at 90°, and then jumped as high as possible with hands on their hips. Throughout both tests, participants were instructed to maintain their hands on their hips to minimize lateral and horizontal displacement, ensuring accurate vertical jump measurement.
Baseline, at the end of the 6 weeks of training and 4 weeks after this (detraining period)
Power
Time Frame: Baseline, at the end of the 6 weeks of training and 4 weeks after this (detraining period)
Power was calculated in both modalities (i.e., HE gravitational and inertial) as the product of velocity and force. The velocity was calculated using the MuscleLab 4020e linear encoder (Ergotest Technology AS, Porsgrunn, Norway). For gravitational loading (i.e. constant mass), the force was calculated as the product of mass and acceleration. For inertial loading, the force was calculated using a force gauge that was anchored along the rope, between a pulley and the proximal end of the second rope.
Baseline, at the end of the 6 weeks of training and 4 weeks after this (detraining period)
Soreness
Time Frame: From session 1 (the beginning of week 1) to session 12 (the end of week 6), at the beginning and end of each session.
Participants were asked "How sore do you feel in your hamstrings?" and rated their soreness on a 10-point Likert Scale (1 = No Soreness, 3 = Minimal Soreness, 5 = Moderate Soreness, 8 = Very Sore, 10 = Extremely Sore)
From session 1 (the beginning of week 1) to session 12 (the end of week 6), at the beginning and end of each session.
Fascicle length
Time Frame: Baseline, at weeks 2 and 3 of the intervention, at the end of the 6 weeks of training and 4 weeks after this (detraining period)

Two-dimensional images of the Biceps femoris long head (BFlh) architecture were captured using B-mode ultrasonography. All imaging was conducted with participants lying prone with their hips and knees in a neutral and fully extended position.Three ultrasound images were taken and stored for analysis through the ImageJ software (National Institutes of Health, USA).

The most visible fascicle in each image was used for measurement of fascicle pennation angle (i.e., angle between the fascicle and the intermediate aponeurosis) and estimation of fascicle length using a validated equation:

FL = sin (AA + 90°) × MT ÷ sin (180° - (AA + 180° - PA))

Baseline, at weeks 2 and 3 of the intervention, at the end of the 6 weeks of training and 4 weeks after this (detraining period)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Rodrigo Martín-San Agustín, University of Valencia

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

September 1, 2019

Primary Completion (Actual)

June 30, 2021

Study Completion (Actual)

June 30, 2021

Study Registration Dates

First Submitted

July 27, 2024

First Submitted That Met QC Criteria

July 31, 2024

First Posted (Actual)

August 5, 2024

Study Record Updates

Last Update Posted (Actual)

August 9, 2024

Last Update Submitted That Met QC Criteria

August 5, 2024

Last Verified

August 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • H1551979435533

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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