Effects Of Maitland's Mobilization At Mid Versus End Range In Knee Osteoarthritis Patients

December 20, 2024 updated by: Riphah International University

Effects Of Maitland's Mobilization At Mid Versus End Range On Pain, Range Of Motion And Functional Disability In Patients With Knee Osteoarthritis.

Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most effective technique among all in decreasing pain sensitivity and increasing range of motion in knee OA.The aim of this study to compare effects of Maitland's mobilization at mid range versus end range on pain. range of motion and functional disability in patients with knee OA, providing useful insights for healthcare professionals to optimize treatment strategies and enhance outcomes in this context.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most effective technique among all in decreasing pain sensitivity and increasing range of motion in knee OA.The aim of this study to compare effects of Maitland's mobilization at mid range versus end range on pain. range of motion and functional disability in patients with knee OA, providing useful insights for healthcare professionals to optimize treatment strategies and enhance outcomes in this context.

This Randomized Clinical Trial will be conducted at DHQ Gujrat through consecutive sampling technique on 44 patients which will be allocated using simple random sampling through sealed opaque enveloped into (Group A and Group B).Maitland's mobilization at end range(Group A) incorporates the end range Maitland's mobilization,strengthening exercises, knee isometrics, transcutaneous electrical stimulation(TENS) and heating pad .

Maitland's mobilization in Mid range (Group B) will be treated with Mid range Maitland's mobilization, TENS,strengthening exercises,knee isometrics and heating pad.Outcomes, encompassing pain levels, range of motion(ROM), and functional disability will be evaluated through Visual analogue scale (VAS),Goniometer and WOMAC scale.The treatment plan spans 4 weeks, comprising 3 sessions per week. Data will be analyzed during SPSS software version 25. After assessing normality of data by Shapiro-wilk test, it will be decided either parametric or non-parametric test will be used within a group or between two groups. Data will be collected at baseline and after 4 weeks of follow up.

Study Type

Interventional

Enrollment (Estimated)

44

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Participants with age between 40 to 60 years.
  • Participants of both genders will be included.
  • Patient with unilateral/bilateral symptomatic tibiofemoral knee OA.
  • Patient suffering from stiffness less than 30 minutes
  • Patients with radiologically diagnosed case of grade 2 knee OA according to the Kellgren and Lawrence scale
  • Patients with reported peak knee pain of >3 on visual analogue scale (VAS)

Exclusion Criteria:

  • Participants with acute inflammation of knee
  • Participants with severe degenerative lumbar spine disease e.g spondylolisthesis
  • Participants with systemic inflammatory arthritic or neurological conditions
  • Participants with intraarticular injection in the prior 3 months
  • Participants with unstable heart condition
  • Participants with received physical therapy of knee in last 3 months

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Maitland's Mobilization in End Range
End-range mobilization will be performed individually in flexion and extension end range of the tibiofemoral joint(0-135 degree).
Other: Maitland's Mobilization in End range
End-range mobilization will be performed individually in flexion and extension end range of the tibiofemoral joint .(0-135 degree)
Experimental: Maitland's Mobilization in Mid Range
Mid range Maitland's mobilization will be performed in (approx. 50-70° knee flexion) of the tibiofemoral joint.
Other: Maitland's mobilization in Mid range
Mid range Maitland's mobilization will be performed in (approx. 50-70° knee flexion) of the tibiofemoral joint

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Numeric Pain Rating Scale
Time Frame: 4 Weeks
The Numerical Pain Rating Scale (NPRS) is a commonly used self-report measure to assess the intensity of pain experienced by individuals. Participants rate their pain on a numerical scale, typically ranging from 0 (no pain) to 10 (worst possible pain).
4 Weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
WOMAC Osteoarthritis INDEX
Time Frame: 4 weeks
The western Ontario and McMaster Universities Arthritis Index(WOMAC) is widely uses in the evaluation of Hip and Knee Osteoarthritis. It is a self administrated questionnaire consisting of 24 item divided into 3 sub-scales: Pain(5items) ,stiffness(2 items) and physical function (17 items)
4 weeks
Universal Goniometer
Time Frame: 4 weeks
It will measure range of motion of Knee
4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Riphah International University

Investigators

  • Principal Investigator: Zainab Amjad Dr., DPT, Riphah International University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

January 10, 2025

Primary Completion (Estimated)

June 25, 2025

Study Completion (Estimated)

June 30, 2025

Study Registration Dates

First Submitted

December 20, 2024

First Submitted That Met QC Criteria

December 20, 2024

First Posted (Actual)

March 25, 2025

Study Record Updates

Last Update Posted (Actual)

March 25, 2025

Last Update Submitted That Met QC Criteria

December 20, 2024

Last Verified

December 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC/RCR&AHS/24/0114

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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