Duration of Postop Analgesia After Inguinal Hernia Surgery Treated with TAP Block Vs II/IH Nerve Block

Comparison of Mean Duration of Postoperative Analgesia in Patients Undergoing Inguinal Hernia Surgery Treated with Transversus Abdominal Plane Block Vs Ilioinguinal and Iliohypogastric Nerve Blocks

Comparing Postop Analgesia after Inguinal Hernia Surgery treated with TAP Block Vs Ilioinguinal/ Iliohypogastric Nerve Block

Study Overview

• Status: Completed
• Conditions: Postoperative Analgesia
• Intervention / Treatment: Drug: Transversus abdominis plane (TAP) block with 0.25 % bupivacaine; Drug: Ilioinguinal/iliohypogastric Nerve Block with 0.25 % bupivacaine

Detailed Description

Comparison of Mean Duration of Postoperative Analgesia in Patients undergoing Inguinal Hernia Surgery treated with Transversus Abdominal Plane Block Versus Ilioinguinal/ Iliohypogastric Nerve Block

• Study Type: Interventional
• Enrollment (Actual): 60
• Phase: Phase 3

Contacts and Locations

Study Locations

• Pakistan
  • Punjab
    • Lahore, Punjab, Pakistan
      • Combined military hospital lahore

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Patients giving written informed consent
• Patients undergoing Inguinal Hernia surgery
• patients with ages 18-60 years
• ASA 1 and 2 patients

Exclusion Criteria:

• INR > 1.0 (patients with bleeding tendency)
• EF < 45 % (patients with cardiac dysfunction)
• FEV1 < 80 % of normal (patients with pulmonary dysfunction)
• patients with renal disease

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Inguinal Hernia Surgery (Group T); Half of the study participants named Group T were administered Ultrasound Guided Transversus Abdominis Plane Nerve Block and the other half named Group I were administered Ilioinguinal & Iliohypogastric Nerve Block before the Inguinal Hernia Surgery.	Drug: Transversus abdominis plane (TAP) block with 0.25 % bupivacaine; The probe was placed in a plane transverse to the lateral abdominal wall in the mid-axillary line immediately cephalad to the iliac crest. The needle was advanced immediately anterior to the probe using the in-plane needle-probe orientation and advanced posteriorly until the needle was observed to penetrate the interface between the internal oblique and transversus abdominis muscles. Thereafter, a local anesthetic (0.2 mL/kg of 0.25 % bupivacaine) was injected incrementally, and the spread was observed within the plane.
Experimental: Inguinal Hernia Surgery (Group I); Half of the study participants named Group T were administered Ultrasound Guided Transversus Abdominis Plane Nerve Block and the other half named Group I were administered Ilioinguinal & Iliohypogastric Nerve Block before the Inguinal Hernia Surgery.	Drug: Ilioinguinal/iliohypogastric Nerve Block with 0.25 % bupivacaine; The ultrasound probe was placed immediately medial and slightly cephalad to the upper aspect of the anterior superior iliac spine to obtain a short-axis view of the nerves situated between the two abdominal muscles (internal oblique and transversus abdominis), A 22 G needle tip ~1 cm caudal to the probe surface was introduced and was advanced until a characteristic 'tenting' of the interface between the two muscles was seen and was then further advanced deep to this interface until a pop was felt and then the injectate (0.2 mL/kg of 0.25 % bupivacaine) was observed spreading between these two layers.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Mean duration of Postoperative Analgesia	The study was conducted to compare the mean duration of postoperative analgesia in patients undergoing inguinal hernia repair surgery treated with transversus abdominis plane block versus the mean duration of postoperative analgesia in patients undergoing inguinal hernia repair surgery treated with ilioinguinal and iliohypogastric nerve block.	6 months

Collaborators and Investigators

• Sponsor: Pakistan Navy Station Shifa Hospital

Study record dates

Study Major Dates

• Study Start (Actual): February 9, 2024
• Primary Completion (Actual): July 28, 2024
• Study Completion (Actual): July 28, 2024

Study Registration Dates

• First Submitted: February 2, 2025
• First Submitted That Met QC Criteria: February 2, 2025
• First Posted (Actual): March 25, 2025

Study Record Updates

• Last Update Posted (Actual): March 25, 2025
• Last Update Submitted That Met QC Criteria: February 25, 2025
• Last Verified: September 1, 2024

More Information

Terms related to this study

• Keywords: nerve block; transversus abdominis plane block; bupivacaine; postoperative analgesia; nerve blocks; TAP block; ultrasound guided nerve block; hernioplasty; transversus abdominis; ultrasound guided nerve blocks; postop analgesia; inguinal hernia surgery; ilioinguinal/ iliohypogastric nerve block; ilioinguinal/iliohypogastric nerve block; abdominal nerve block; 0.25% bupivacaine; 0.25 percent bupivacaine; internal oblique; IIN; IHN; IIN/ IHN; II/ IH nerve block; transversus abdominis muscle; ilioinguinal muscle; iliohypogastric muscle
• Additional Relevant MeSH Terms: Neurologic Manifestations; Nervous System Diseases; Pathological Conditions, Anatomical; Neurobehavioral Manifestations; Hernia, Abdominal; Perceptual Disorders; Hernia; Hernia, Inguinal; Agnosia; Physiological Effects of Drugs; Peripheral Nervous System Agents; Anesthetics, Local; Anesthetics; Central Nervous System Depressants; Sensory System Agents; Bupivacaine
• Other Study ID Numbers: 530/ 2024

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No