The Outcome of Three Weeks Rehabilitation in Patients With a Total Hip or Knee Replacement Experiencing Persistent Physical Impairments (Rehab-hip-knee)

Patients with total hip or knee replacement experiencing persistant problems are offered 3 weeks of intensive rehabilitation.

Study Overview

• Status: Recruiting
• Conditions: Hip Osteoarthritis; Knee Osteoarthristis
• Intervention / Treatment: Other: Rehabilitation

Detailed Description

Outcomes before, at the end of treatment and at 6 months follow up will be investigated. Data will be handled separately for the two groups of patients: 42 with a total hip replacement and 42 with a total knee replacement. Specific and generic outcomes will be collected.

• Study Type: Observational
• Enrollment (Estimated): 84

Contacts and Locations

• Study Contact: Name: Signe Kierkegaard-Brøchner, PhD; Phone Number: 004578427882; Email: signkier@rm.dk

Study Locations

• Denmark
  • Brædstrup, Denmark
    • Recruiting
    • Horsens Regional Hospital
    • Contact: Signe Kierkegaard-Brøchner, PhD; Phone Number: 004578427882; Email: signkier@rm.dk
    • Principal Investigator: Signe Kierkegaard-Brøchner, PhD
    • Sub-Investigator: Stian Langgård Jørgensen, PhD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patients who have a total hip or knee replacement experiencing persistant problems, hence are admitted to a 3 week intensive rehabilitation period.

Description

Inclusion Criteria:

- Patients with a total hip or knee replacement admitted for intensive rehabilitation

Exclusion Criteria:

• Patients unable to understand Danish
• Unable to participate in physical tests
• Unable to understand questionaires
• Unable to participate i 6 months follow up

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Intervention group hip; Patients with a total hip replacement undergoing rehabilitation	Other: Rehabilitation; Three weeks intensive rehabilitation where patients undergo group-based and individualised rehabilitation focusing at improving pain, function and quality of life for the patient
Intervention group knee; Patients with a total hip replacement undergoing rehabilitation	Other: Rehabilitation; Three weeks intensive rehabilitation where patients undergo group-based and individualised rehabilitation focusing at improving pain, function and quality of life for the patient

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
HOOS/KOOS pain (0-100 score)	Hip or knee related pain	Change from baseline (0) to 3 weeks
HOOS/KOOS ADL (0-100 score)	Hip or knee related activities of daily living	Change from baseline (0) to 3 weeks
HOOS/KOOS quality of life (0-100 score)	Hip or knee related quality of life	Change from baseline (0) to 3 weeks
HOOS/KOOS pain (0-100 score)	Hip or knee related pain	Change from 3 weeks to 7 months
HOOS/KOOS ADL (0-100 score)	Hip or knee related activities of daily living	Change from 3 weeks to 7 months
HOOS/KOOS quality of life (0-100 score)	Hip or knee related quality of life	Change from 3 weeks to 7 months
Sit-to-stand test	Number of completed sit to stands in 30 seconds	Change from baseline (0) to 3 weeks
Sit-to-stand test	Number of completed sit to stands in 30 seconds	Change from 3 weeks to 7 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Patient acceptable symptom state (yes/no)	Patients are asked with a single question if their current symptom state is acceptable	3 weeks follow up
Patient acceptable symptom state (yes/no)	Patients are asked with a single question if their current symptom state is acceptable	7 months follow up
HOOS/KOOS symptoms (0-100 score)	Hip or knee related symptoms	Change from baseline (0) to 3 weeks
HOOS/KOOS symptoms (0-100 score)	Hip or knee symptoms	Change from 3 weeks to 7 months
HOOS/KOOS sport/rec (0-100 score)	Hip or knee related sport/rec	Change from baseline (0) to 3 weeks
HOOS/KOOS sport/rec (0-100 score)	Hip or knee related sport/rec	Change from 3 weeks to 7 months
6 minute walk test	The distance a patient can walk in 6 minutes	Change from baseline (0) to 3 weeks
6 minute walk test	The distance a patient can walk in 6 minutes	Change from 3 weeks to 7 months
40 meter fast paced walk test	The time a patient uses walking 40 meters fast	Change from baseline (0) to 3 weeks
40 meter fast paced walk test	The time a patient uses walking 40 meters fast	Change from 3 weeks to 7 months
Stair test	The time a patient uses to ascend and decend a staircase	Change from baseline (0) to 3 weeks
Stair test	The time a patient uses to ascend and decend a staircase	Change from 3 weeks to 7 months
Pain catastrophising scale (0-52 score)	Current level of pain catastrophising with 0 being the best	Baseline
Pain catastrophising scale (0-52 score)	Current level of pain catastrophising with 0 being the best	3 weeks
Pain catastrophising scale (0-52 score)	Current level of pain catastrophising with 0 being the best	7 months
Global rating of change (0-11 score)	Likert scale where patients indicate their overall rating of change since the beginning of the intervention	Change from baseline to 3 weeks
Global rating of change (0-11 score)	Likert scale where patients indicate their overall rating of change since the beginning of the intervention	Change from baseline to 7 months
The 5-level EQ-5D version (EQ-5D-5L) (0-5 scale)	EQ5D5L scores	Change from baseline (0) to 3 weeks
The 5-level EQ-5D version (EQ-5D-5L) (0-5 scale)	EQ5D5L scores	Change from 3 weeks to 7 mothns
EQ5D VAS (0-100 scale)	EQ5D Vas overall health	Change from baseline (0) to 3 weeks
EQ5D VAS (0-100 scale)	EQ5D Vas overall health	Change from 3 weeks to 7 months

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Patient acceptable symptom state (yes/no)	Patients are asked with a single question if their current symptom state is acceptable	Baseline
Employment status (yes/no/part time)		Baseline
Employment status (yes/no/part time)		7 months

Collaborators and Investigators

• Sponsor: Horsens Hospital
• Collaborators: VIA University College

Study record dates

Study Major Dates

• Study Start (Actual): August 25, 2025
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): December 31, 2027

Study Registration Dates

• First Submitted: July 30, 2025
• First Submitted That Met QC Criteria: July 30, 2025
• First Posted (Actual): August 6, 2025

Study Record Updates

• Last Update Posted (Estimated): August 26, 2025
• Last Update Submitted That Met QC Criteria: August 25, 2025
• Last Verified: August 1, 2025

More Information

Terms related to this study

• Keywords: knee osteoarthritis; rehabilitation; total knee replacement; total hip replacement; hip osteoartritis
• Additional Relevant MeSH Terms: Musculoskeletal Diseases; Arthritis; Joint Diseases; Rheumatic Diseases; Osteoarthritis; Osteoarthritis, Knee; Osteoarthritis, Hip; Therapeutics; Patient Care; Health Services; Health Care Facilities Workforce and Services; Aftercare; Continuity of Patient Care; Rehabilitation
• Other Study ID Numbers: 1-16-02-329-25

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No