AI Based Physiotherapy 3- and 9-Month Follow-Up in Oral Cancer Patients

December 8, 2025 updated by: National Taiwan University Hospital

Effects of AI Based Physiotherapy on Mandibular Mobility Shoulder Function Whole Body Physical Function Quality of Life and Return to Work in Oral Cancer Patients: 3- and 9-Month Postintervention Follow-Up

This follow-up clinical study aims to evaluate the sustained effects of two rehabilitation programs (AI-based physiotherapy vs. conventional physiotherapy) for oral cancer patients. Participants who completed the original intervention trial (ClinicalTrials.gov ID: 202411044RINC) will be assessed at 3 and 9 months post-intervention. Outcomes include mandibular mobility, shoulder joint range of motion, functional performance, quality of life, pain, and return-to-work status.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

This study is a continuation of our prior trial (ClinicalTrials.gov ID: 202411044RINC), which investigated the short-term effects of AI-based physiotherapy compared with conventional physiotherapy in oral cancer patients.

The current follow-up phase evaluates both groups at 3 and 9 months post-intervention to determine whether initial improvements are maintained and whether they translate into better long-term physical function, quality of life, and return-to-work outcomes. No additional interventions will be delivered; only follow-up assessments are planned.

Study Type

Interventional

Enrollment (Estimated)

65

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Taiwan
      • Taipei, Taiwan, 100
        • Recruiting
        • School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan
        • Contact:
          • Yueh-Hsia Chen, Ph.D
        • Principal Investigator:
          • Yueh-Hsia Chen, Ph.D

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Participants who completed the intervention phase of the previous trial (202411044RINC)
  • Age 20-65 years
  • Able to attend follow-up assessments at 3 and 9 months

Exclusion Criteria:

  • Withdrawal from the original trial
  • Cancer recurrence or new cancer-related treatment interfering with functional assessment
  • Unable to communicate or comply with follow-up visits

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Experimental group (Follow-up)
Participants who originally received AI-based physiotherapy will undergo follow-up assessments at 3 and 9 months post-intervention.
Other: AI-based physiotherapy follow-up assessments
AI-based physiotherapy and 3 and 9 months follow-up assessments
Active Comparator: Control group (Follow-up)
Participants who originally received conventional physiotherapy will undergo follow-up assessments at 3 and 9 months post-intervention.
Other: conventional physiotherapy follow-up assessments
conventional physiotherapy and 3 and 9 months follow-up assessments

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Disabilities of the Arm, Shoulder, and Hand outcome questionnaire
Time Frame: 3 months, 9 months post-intervention
A total scale from 1 to 100. Higher scores indicate greater disability
3 months, 9 months post-intervention
EORTC QLQ-C30 questionnaire
Time Frame: 3 months, 9 months post-intervention
A total scale from 1 to 100. Higher scores indicate greater function
3 months, 9 months post-intervention

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Return-to-work status
Time Frame: 3 months, 9 months post-intervention
yes/no, time to return, % returned
3 months, 9 months post-intervention

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan University Hospital

Investigators

  • Principal Investigator: Yueh-Hsia Chen, Ph.D., National Taiwan University, College of Medicine

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 6, 2025

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2027

Study Registration Dates

First Submitted

October 2, 2025

First Submitted That Met QC Criteria

November 17, 2025

First Posted (Estimated)

November 20, 2025

Study Record Updates

Last Update Posted (Actual)

December 16, 2025

Last Update Submitted That Met QC Criteria

December 8, 2025

Last Verified

October 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 202412109RIND

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Oral Cancer

Clinical Trials on AI-based physiotherapy follow-up assessments

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belarus

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe