REDS SCORE VERSUS qSOFA SCORE to Predict Mortality in Patients With Suspected Sepsis
Risk-stratification of Emergency Department Suspected Sepsis (REDS) Score Versus Quick Sequential Organ Failure Assessment (qSOFA) Score to Predict Mortality in Patients With Suspected Sepsis
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
Sepsis is a life threatening condition and a major cause of morbidity and mortality in emergency department worldwide.Patients at high-risk of death may be identified by using an evidence based risk-stratification score. The ED is a busy and hard environment and any score that is used should be easy to calculate using readily available variables. The objective criteria defining sepsis, a minimum two-point increase as in qSoFA score .
The REDS (Risk-stratification of Emergency Department suspected Sepsis) score is a tool used to assess the risk of mortality in patients with suspected sepsis in the emergency department. It combines several factors including age, altered mental state, respiratory rate, systolic blood pressure, serum albumin, INR, lactate levels, and refractory hypotension. A score of 3 or more is considered high-risk. Our goal in this work is to compare the predictive accuracy of the REDS score versus qSOFA in identifying in-hospital mortality among ED patients with suspected sepsis and improving outcomes in ED patients.
The REDS score includes the following variables, each assigned a point value:
Age: ≥ 65 years old (1 point) Altered Mental State: (1 point) Respiratory Rate: ≥ 22 breaths/min (1 point) Systolic Blood Pressure: ≤ 100 mm Hg (1 point) Serum Albumin: ≤ 27 g/L (1 point) INR: ≥ 1.3 (1 point) Lactate: 2.1-3.9 mmol/L (1 point), ≥ 4 mmol/L (3 points) Refractory Hypotension: (2 points for lactate ≤ 2 mmol/L, 3 points for lactate >2 mmol/L)
Interpreting the REDS score:
0-2: Low risk of death 3 or more: High risk of death The REDS score is a useful tool for emergency departments to quickly identify patients who may be at higher risk of mortality from sepsis and need more aggressive or immediate treatment.The quick SOFA (qSOFA) score is a bedside tool used to quickly assess the risk of death or prolonged intensive care unit stay in patients with suspected infection. It uses three criteria: respiratory rate, altered mental status, and systolic blood pressure. A score of 2 or more indicates a higher risk.
qSOFA Criteria:
- Respiratory Rate: 22 breaths per minute or higher.
- Altered Mental Status: A Glasgow Coma Scale score less than 15.
- Systolic Blood Pressure: 100 mmHg or lower.
Scoring:
Each criterion met scores 1 point. A score of 2 or more indicates a higher risk of poor outcome. qSOFA helps identify patients with suspected infection who are likely to have sepsis. It is a rapid assessment tool that can be used in urgent and resource-limited settings
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Mostafa Nageh mohamed, M.B.B. Ch
- Phone Number: +01119618014
- Email: mostafanageh999@gmail.com
Study Contact Backup
- Name: Bassant said Mousa Associate Prof of Emergency department Faculty of medicine, Study Principal Investigator
- Phone Number: 01227062927
Study Locations
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Abo Tig
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Asyut, Abo Tig, Egypt, 71641
- assiut
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- Adults ≥ 18 y presented to the ED with suspected or confirmed infection, both sex qSOFA criterion met on arrival ≥ 2
Exclusion Criteria:
- Patient less than 18 years Incomplete vital sign records upon ED arrival Pregnant patients Those with DNR state Immune compromised patient as leukemia
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
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Patients will be randomly assigned to two groups: 1) Group A 2)Group B
Patients will be randomly assigned to two groups:
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Mercury sphygmomanometer for measuring blood pressure
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Primary outcome
Time Frame: 30 day
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primary outcome will be mortality during the 30 day follow-up
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30 day
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Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Mohamed Anwar, Consultant of Anathesia ICU, Assiut University
- Study Director: Haitham Mohammed Ahmed, Lecturer of Anesthesia,ICU, Assiut University
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimated)
Study Record Updates
Last Update Posted (Estimated)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- Reds score versus qSOFA score
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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