Comparison of Eversion and Conventional Techniques in Carotid Endarterectomy

January 1, 2026 updated by: İsmail DAL, Kastamonu University

Comparison of Operative and Early Postoperative Outcomes Between Eversion and Conventional Techniques in Carotid Endarterectomy

Atherosclerotic carotid artery disease is responsible for approximately 20% of strokes worldwide, and its treatment options include medical therapy, surgery, and stenting.Surgical management is prioritized over medical and stent based approaches and can be performed using either the conventional methed closed primarily or with a patch or the eversion technique.The aim of this study was to compare the intraoperative and early postoperative outcomes of the eversion technique and the conventional method with primary closure.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

129

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
      • Istanbul, Turkey (Türkiye)
        • Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

Carotid endarterectomy was performed in patients with 50-99% stenosis who had experienced stroke or transient ischemic attack (TIA) within the last six months, as well as in asymptomatic patients with 70-99% stenosis. These patients were divided into two groups according to the surgical technique applied conventional or eversion carotid endarterectomy and intraoperative and early postoperative outcomes were compared between the groups.

Description

Inclusion Criteria:

-Patients undergoing isolated carotid endarterectomy, either emergently or electively

Exclusion Criteria:

  • Patients younger than 18 years of age
  • Patients scheduled for concomitant cardiac surgery
  • Reoperations

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Conventional endarterectomy
Who were performed conventional,primarily endarterectomy patients are included this group
Procedure: Carotid endarterectomy, conventional
In this study, patients were divided into two groups according to whether they underwent conventional or eversion endarterectomy. Although the eversion technique is the oldest method, the conventional approach is still widely performed due to its ease of application, despite not being recommended in current guidelines. Therefore, our aim is to contribute to the literature by comparing these two methods. The conventional method is performed with a longitudinal incision extending from the common carotid artery (CCA) to the internal carotid artery (ICA) up to the end of the plaque. The arteriotomy is then closed either primarily or with the use of a patch. In our study, we performed only the primary closure method..
Eversion
Who were performed eversion endarterectomy patients are included this group
Procedure: Carotid endarterectomy, eversion
In this study, patients were divided into two groups according to whether they underwent conventional or eversion endarterectomy. Although the eversion technique is the oldest method, the conventional approach is still widely performed due to its ease of application, despite not being recommended in current guidelines. Therefore, our aim is to contribute to the literature by comparing these two methods.The eversion method is performed by transecting the internal carotid artery (ICA) from the common carotid artery (CCA). The arteriotomy is then closed in an end to side fashion.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Number of participants with stroke and death
Time Frame: 30 days
All strokes and/or deaths occurring within 30 days after surgery
30 days
Number of participants with symptoms of occlusion
Time Frame: Postoperative 30 days
Early carotid restenosis or occlusion within 30 days after surgery
Postoperative 30 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Kastamonu University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 15, 2025

Primary Completion (Actual)

August 30, 2025

Study Completion (Actual)

September 30, 2025

Study Registration Dates

First Submitted

December 4, 2025

First Submitted That Met QC Criteria

December 4, 2025

First Posted (Estimated)

December 17, 2025

Study Record Updates

Last Update Posted (Actual)

January 6, 2026

Last Update Submitted That Met QC Criteria

January 1, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KastamanuU

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Endarterectomy, Carotid

Clinical Trials on Carotid endarterectomy, conventional

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mali

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe