BPIT 5-Line Pilot: Interventional Study on Strength, HRV & Injury Risk Reduction (n=23) (BPIT 5-Line)

A Prospective, Single-Center, Interventional Study to Evaluate the 5-Line Principle of Balanced Intensity Training (BPIT) for Enhancing Physical Performance and Reducing Injury Risk

This prospective, single-center, interventional pilot (n=23) evaluates the 5-Line Principle of Balanced Intensity Training (BPIT) over 6 weeks at GFFI Fitness Academy. Participants (18 males aged 22-48, 5 females aged 20-33) will receive BPIT 5-Line Training (3 sessions/week, 6 weeks). No control group. Conducted July 1 - November 30, 2024.

Progressive intensity via anatomical lines: 1. Ground-Based (Low Intensity); 2. Knee-Level (Low-Moderate); 3. Standing (Moderate); 4. Head-Level (Moderate-High); 5. Plyometric/High-Impact (High). Aims to assess changes in strength, HRV, and injury risk.

Study Overview

• Status: Completed
• Conditions: Healthy
• Intervention / Treatment: Behavioral: BPIT 5-Line Training

Detailed Description

STUDY DESIGN: Prospective, single-center, interventional pilot (n=23) with single-group assignment. All participants receive the BPIT 5-Line intervention. Assessments at baseline and Week 6.

INTERVENTION: BPIT 5-Line Training: 3 x 60-minute sessions/week for 6 weeks, progressing across five intensity lines: 1. Ground-Based (Low Intensity, e.g., prone planks); 2. Knee-Level (Low-Moderate, e.g., shoulder press); 3. Standing (Moderate, e.g., half-squat); 4. Head-Level (Moderate-High); 5. Plyometric/High-Impact (High Intensity). Specific exercises detailed in Training Protocol Manual.

OBJECTIVES: Primary - Evaluate BPIT's impact on 1RM strength (e.g., squat, bench press, deadlift) and training-related injury incidence. Secondary - Assess changes in HRV (RMSSD), HRR (bpm in 60s), EMG muscle activation, joint biomechanics (knee valgus, spinal curvature), adherence (% sessions completed), and participant feedback (questionnaires).

• Study Type: Interventional
• Enrollment (Actual): 23
• Phase: Not Applicable

Contacts and Locations

Study Locations

• India
  • National Capital Territory of Delhi
    • New Delhi, National Capital Territory of Delhi, India, 110026
      • GFFI Fitness Academy

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Healthy adults aged 22-65 years
• Regular fitness trainees (≥2 sessions/week prior)
• Able to provide informed consent
• No recent musculoskeletal injury (past 3 months)

Exclusion Criteria:

• - Cardiovascular disease or uncontrolled hypertension
• Current musculoskeletal injury or surgery (past 6 months)
• Neurological disorders affecting movement
• Pregnancy
• Use of performance-enhancing substances

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: BPIT 5-Line Training; All 23 participants (18 males aged 22-48, 5 females aged 20-33) received BPIT 5-Line Training (3-5 sessions/week, 6 weeks). Intensity progressed via 5 Lines: Ground-Based, Low Intensity; Knee-Level, Low-Moderate Intensity; Standing, Moderate Intensity; Head-Level, Moderate-High Intensity; Plyometric/High-Impact, High Intensity	Behavioral: BPIT 5-Line Training; All 23 participants received BPIT 5-Line Training (3-5 sessions/week, 6 weeks). Intensity progressed via 5 anatomical lines: 1. Ground-Based, Low Intensity; 2. Knee-Level, Low-Moderate; 3. Standing, Moderate; 4. Head-Level, Moderate-High; 5. Plyometric/High-Impact, High Intensity. Sessions 45-60 min, monitored via HRV, pain, fatigue.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in 1RM Strength	Change in one-repetition maximum (1RM) strength for key exercises (e.g., squat, bench press) from baseline to week 6. Measured in kilograms (kg) using standard 1RM testing protocol. Time Frame: Baseline to Week 6 Unit of Measure: kilograms (kg)	6 weeks
Injury Incidence	Number of new musculoskeletal injuries reported during the study period, defined as any complaint requiring medical attention, training modification, or rest exceeding 1 day. Measured as incidence rate per 100 participant-weeks (normalized for exposure in this 23-participant pilot). Unit of Measure: injuries per 100 participant-weeks	Baseline to Week 6

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in Heart Rate Variability (HRV)	Change in Heart Rate Variability (RMSSD) from baseline to week 6, measured via 60-second daily monitoring using HRV device/app. Time Frame: Baseline to Week 6 Unit of Measure: milliseconds (ms)	Week 6
Change in Muscle Activation (EMG Amplitude)	Change in Electromyography (EMG) amplitude for key muscle groups during specific exercises from baseline to week 6, measured as percentage of maximum voluntary contraction (%MVC) using EMG equipment. Time Frame: Baseline to Week 6 Unit of Measure: percentage of maximum voluntary contraction (%MVC)	Baseline to Week 6
Change in Joint Biomechanics (Knee Valgus and Spinal Curvature)	Change in knee valgus and spinal curvature angles during functional movements from baseline to week 6, measured in degrees via 3D motion analysis or goniometer. Time Frame: Baseline to Week 6 Unit of Measure: degrees	Baseline to Week 6
Training Adherence	Percentage of completed training sessions from baseline to week 6, measured via session logs. Time Frame: Baseline to Week 6 Unit of Measure: percentage	Baseline to Week 6
Participant Feedback	Qualitative feedback from post-study questionnaires, scored on a Likert scale (1-5) for satisfaction and perceived benefit. Time Frame: Week 6 Unit of Measure: units on a scale (1-5)	6 weeks
Heart Rate Recovery (HRR)	Change in Heart Rate Recovery (bpm decrease in 60 seconds post-exercise) from baseline to week 6, measured via HR monitor. Time Frame: Baseline to Week 6 Unit of Measure: beats per minute (bpm)	6 Weeks

Collaborators and Investigators

• Sponsor: MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.

Publications and helpful links

Helpful Links

• Complete Study Documentation Package - BPIT 5-Line Pilot (Protocol, Ethics, Consent, Logs, AE, Report, Closeout)

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2024
• Primary Completion (Actual): November 30, 2024
• Study Completion (Actual): November 30, 2024

Study Registration Dates

• First Submitted: November 18, 2025
• First Submitted That Met QC Criteria: December 8, 2025
• First Posted (Actual): December 22, 2025

Study Record Updates

• Last Update Posted (Actual): December 22, 2025
• Last Update Submitted That Met QC Criteria: December 8, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: BPIT-GFFI-2024-001; Other → MMSx Authority (Other Grant/Funding Number: MMSx Authority)

Plan for Individual participant data (IPD)

Study Data/Documents

1. Individual Participant Data Set
   Information identifier: BPIT-GFFI-2024-001
   Information comments: De-identified individual participant data (strength, HRV, knee valgus, injury logs) available upon reasonable request to Principal Investigator: Dr. Neeraj Mehta, PhD (info@mmsxauthority.com). All supporting documents (Protocol, Ethics, Consent, Observation Logs, AE Forms, Final Report) uploaded under "Study Documents" tab.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No