The Impact of Mindfulness-Based Psychoeducation on Perceived Stress, Intolerance of Uncertainty, and Cognitive Flexibility in Patients With Anxiety Disorders (Anxiety)

January 7, 2026 updated by: Eda Mert, Aydin Adnan Menderes University

The Impact of Mindfulness-Based Psychoeducation on Perceived Stress, Intolerance of Uncertainty, and Cognitive Flexibility in Patients With Anxiety Disorders: A Randomized Controlled Trial

Mindfulness-based interventions, which cultivate the capacity to remain present with difficult thoughts and emotions and to maintain psychological well-being in the face of such challenges, have been shown to facilitate positive change in individuals with anxiety disorders. The present study aimed to investigate the effects of a mindfulness-based psychoeducational program on perceived stress, intolerance of uncertainty, and cognitive flexibility among individuals diagnosed with anxiety disorders.

This randomized controlled trial with pre-test, post-test, and one-month follow-up measurements was conducted with individuals who applied to the Psychiatry Outpatient Clinic at Aydın Atatürk State Hospital and were diagnosed with anxiety disorders. A total of 50 participants were included in the study and were randomly assigned to groups (Experimental: 25; Control: 25). The experimental group underwent an 8-week mindfulness-based psychoeducational program, while no intervention was provided to the control group. Research data were collected using the Personal Information Form, Perceived Stress Scale (PSS), Intolerance of Uncertainty Scale (IUS-12), and Cognitive Flexibility Scale (CFS).

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

50

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Being literate
  • Having a diagnosed anxiety disorder
  • Being 18 years of age or older

Exclusion Criteria:

  • Presence of an acute episode of the illness
  • Lack of ability to engage in communication
  • currently receiving another form of psychotherapy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Intervention
Participants receive a structured mindfulness-based psychoeducation programin addition to standard care. The intervention includes psychoeducational sessions, mindfulness exercises, and practical strategies.
Other: Mindfulness-Based Psychoeducational Program
Mindfulness-Based Psychoeducational Program contains 8-sessions named as "Introduction to mindfulness, Exploring Mindfulness, Becoming Mindful of the Autopilot, Being in the Body, Meeting Stress with Mindfulness, Mindful Communication, Staying with Difficulties, A New Beginning"
No Intervention: Control
Participants receive standard care only without any additional psychoeducational or mindfulness-based intervention.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Perceived Stress Scale
Time Frame: Pre-test; post-test (at the end of 8-week psychoeducational program); 1-month follow-up test
Differences in participants' perceived stress levels pre- and post-psychoeducation. Higher scores obtained from the scale indicate greater levels of perceived stress.
Pre-test; post-test (at the end of 8-week psychoeducational program); 1-month follow-up test
Intolerance of Uncertainty Scale
Time Frame: Pre-test; post-test (at the end of 8-week psychoeducational program); 1-month follow-up test
Differences in participants' intolerance of uncertainty levels pre- and post-psychoeducation. Higher scores obtained from the scale indicate greater levels of intolerance of uncertainty.
Pre-test; post-test (at the end of 8-week psychoeducational program); 1-month follow-up test
Cognitive Flexibility Scale
Time Frame: Pre-test; post-test (at the end of 8-week psychoeducational program); 1-month follow-up test
Differences in participants' cognitive flexibility levels pre- and post-psychoeducation. Higher scores on the scale indicate higher levels of cognitive flexibility.
Pre-test; post-test (at the end of 8-week psychoeducational program); 1-month follow-up test

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Aydin Adnan Menderes University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 1, 2023

Primary Completion (Actual)

June 1, 2024

Study Completion (Actual)

November 1, 2024

Study Registration Dates

First Submitted

November 23, 2025

First Submitted That Met QC Criteria

December 9, 2025

First Posted (Estimated)

December 23, 2025

Study Record Updates

Last Update Posted (Actual)

January 9, 2026

Last Update Submitted That Met QC Criteria

January 7, 2026

Last Verified

December 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2023/369

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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