Web-based Platform for Nutrition Management in Patients With Cancer

Web-based Platform for Nutrition Management in Patients With Cancer: A Randomized Clinical Trial

It is crucial to promptly identify nutritional issues in these patients within the community and provide them with dietary guidance, nutritional counseling, and support. This study will be conducted in communities in Chengdu, Sichuan. Community management teams will register oncology patients, collecting information such as demographic data, tumor type, stage, specific treatment plan, treatment hospital, regularity of hospital admissions, and frequency of independent smartphone use. Registered patients will be screened based on inclusion and exclusion criteria. For those who meet the criteria, the community management team will contact them and recommend the use of a dedicated app developed by the research team. An initial nutritional assessment will also be conducted. Patients identified with nutritional risks will be directly referred to the research team's clinical nutritionists for face-to-face consultations. After additional tests, such as body composition analysis, necessary nutritional education and stepwise nutritional interventions will be provided. These patients will also use the app for dietary monitoring and nutritional guidance. For patients without nutritional risks, the app will be recommended for daily questionnaire completion and activity tracking.

Study Overview

• Status: Recruiting
• Conditions: Nutrition
• Intervention / Treatment: Other: nutrtion care based on app

• Study Type: Interventional
• Enrollment (Estimated): 84
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Xingchen Peng; Phone Number: 18980606753; Email: pxx2014@163.com

Study Locations

• China
  • Sichuan
    • Chengdu, Sichuan, China, 610041
      • Recruiting
      • West China Hospital
      • Contact: Xingchen Peng; Phone Number: 18980606753; Email: pxx2014@163.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Pathologically confirmed malignant tumor;
• PG-SGA score of 4-9 points;
• Age: ≥18 years, with an expected survival time of more than 1 year;
• Possesses adequate cognitive and reading abilities to complete questionnaires and use the APP.

Exclusion Criteria:

• Presence of neurological or psychiatric disorders affecting cognitive function, including central nervous system metastasis of tumors;
• Suffering from conditions severely impacting digestion, metabolism, or food intake;
• Patients in the cachexia stage or refractory cachexia phase.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: intervention group; Self-Intervention: During the period of staying at home, patients use the app developed by the team for self-intervention, including dietary monitoring and check-ins, nutritional risk assessment, learning of educational knowledge, and online expert consultations. Community Intervention: When nutritional risks are detected, pop-up alerts will notify patients to communicate with the community management team. Patients can seek basic nutritional consultations and receive advice from the community management team. If necessary, the management team will refer patients to relevant higher-level hospital outpatient clinics for further care. If patients experience other issues related to their primary condition, the community management team will refer them to community healthcare providers for consultation and treatment. The community will also organize thematic lectures on nutritional management for cancer patients, with oncologists and nutritionists providing regular voluntary consultatio	Other: nutrtion care based on app; Self-Intervention: During the period of staying at home, patients use the app developed by the team for self-intervention, including dietary monitoring and check-ins, nutritional risk assessment, learning of educational knowledge, and online expert consultations. Community Intervention: When nutritional risks are detected, pop-up alerts will notify patients to communicate with the community management team. Patients can seek basic nutritional consultations and receive advice from the community management team. If necessary, the management team will refer patients to relevant higher-level hospital outpatient clinics for further care. If patients experience other issues related to their primary condition, the community management team will refer them to community healthcare providers for consultation and treatment. The community will also organize thematic lectures on nutritional management for cancer patients, with oncologists and nutritionists providing regular voluntary consultation
No Intervention: standard care; standard nutrtion care

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
body weight change	change of body weight during the trail	baseline, pre-intervention；every 2 weeks after randomization until 6 moths.

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
PG-SGA	assessed using the PG-SGA score	baseline, pre-intervention；every 2 weeks after randomization until 6 moths.
NRS2002	using nutrition risk screening [NRS 2002]	baseline, pre-intervention；every 2 weeks after randomization until 6 moths.

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
EORTC QLQ C30	using Quality-of-Life Questionnaire Core 30	baseline, pre-intervention；every 4 weeks after randomization until 6 moths.
caregiver burden	using the 12-Item Zarit Burden Interview [ZBI]	baseline, pre-intervention；every 4 weeks after randomization until 6 moths.
psychology characteristics	Hospital Anxiety and Depression Scale [HADS]	baseline, pre-intervention；every 4 weeks after randomization until 6 moths.

Collaborators and Investigators

• Sponsor: Xingchen Peng

Study record dates

Study Major Dates

• Study Start (Estimated): December 30, 2025
• Primary Completion (Estimated): October 30, 2026
• Study Completion (Estimated): April 30, 2027

Study Registration Dates

• First Submitted: November 17, 2025
• First Submitted That Met QC Criteria: December 14, 2025
• First Posted (Actual): December 29, 2025

Study Record Updates

• Last Update Posted (Actual): December 29, 2025
• Last Update Submitted That Met QC Criteria: December 14, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Keywords: cancer
• Additional Relevant MeSH Terms: Neoplasms
• Other Study ID Numbers: 2024-2316

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No